Targeted expression of a human pituitary tumor-derived isoform of FGF receptor-4 recapitulates pituitary tumorigenesis - Wikidata - awgldk - TriplyDB

Targeted expression of a human pituitary tumor-derived isoform of FGF receptor-4 recapitulates pituitary tumorigenesis

Targeted expression of a human pituitary tumor-derived isoform of FGF receptor-4 recapitulates pituitary tumorigenesis

http://www.wikidata.org/entity/Q28344662

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Best Practice No 172: pituitary gland pathology Human Pituitary Adenoma Proteomics: New Progresses and Perspectives Pituitary adenomas: historical perspective, surgical management and future directions Functional roles of fibroblast growth factor receptors (FGFRs) signaling in human cancers Identification of FGFR4-activating mutations in human rhabdomyosarcomas that promote metastasis in xenotransplanted models.Mechanisms for pituitary tumorigenesis: the plastic pituitary.Is fibroblast growth factor receptor 4 a suitable target of cancer therapy?Genetically engineered mouse models of pituitary tumors Molecular mechanisms of pituitary organogenesis: In search of novel regulatory genes.The FGFR4-G388R polymorphism promotes mitochondrial STAT3 serine phosphorylation to facilitate pituitary growth hormone cell tumorigenesis Cellular and molecular specificity of pituitary gland physiology.Deficiency of metabolic regulator FGFR4 delays breast cancer progression through systemic and microenvironmental metabolic alterations.Loss of heterozygosity and DNA methylation affect germline fibroblast growth factor receptor 4 polymorphism to direct allelic selection in breast cancer FGFR4 profile as a prognostic marker in squamous cell carcinoma of the mouth and oropharynx.Anterior pituitary adenomas: inherited syndromes, novel genes and molecular pathways.Persistent ERK/MAPK activation promotes lactotrope differentiation and diminishes tumorigenic phenotype.FGFR4 role in epithelial-mesenchymal transition and its therapeutic value in colorectal cancer Fibroblast growth factors in cancer: therapeutic possibilities.The pathogenesis of pituitary tumours.DFG-out mode of inhibition by an irreversible type-1 inhibitor capable of overcoming gate-keeper mutations in FGF receptors.Pituitary tumour transforming gene in endocrine cancer.Epigenetic silencing through DNA and histone methylation of fibroblast growth factor receptor 2 in neoplastic pituitary cells The molecular pathogenetic role of cell adhesion in endocrine neoplasia.Animal models of pituitary neoplasia Keratinocyte growth factor expression and activity in cancer: implications for use in patients with solid tumors.Mechanisms of disease: The pathogenesis of pituitary tumors.Further observations on the relationship between the FGFR4 Gly388Arg polymorphism and lung cancer prognosis G388R mutation of the FGFR4 gene is not relevant to breast cancer prognosis.A study of the correlation between morphological findings and biological activities in clinically nonfunctioning pituitary adenomas.Fibroblast growth factor receptor 4 (FGFR4): a targetable regulator of drug resistance in colorectal cancer.The cancer-associated FGFR4-G388R polymorphism enhances pancreatic insulin secretion and modifies the risk of diabetes.A call to ARMS: targeting the PAX3-FOXO1 gene in alveolar rhabdomyosarcoma.Genomic approaches to problems in pituitary neoplasia.Epidemiology and etiopathogenesis of pituitary adenomas.The role of genetic and epigenetic changes in pituitary tumorigenesis.The insulin resistance Grb14 adaptor protein promotes thyroid cancer ret signaling and progression.Distinct transcriptional control and action of fibroblast growth factor receptor 4 in differentiating skeletal muscle cells.Fibroblast growth factor receptor 4 as a potential prognostic and therapeutic marker in colorectal cancer.Pituitary adenomas in man and mouse: oncogenic potential of a truncated fibroblast growth factor receptor 4.Inhibition of human bladder tumour cell growth by fibroblast growth factor receptor 2b is independent of its kinase activity. Involvement of the carboxy-terminal region of the receptor.

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P2860

Targeted expression of a human pituitary tumor-derived isoform of FGF receptor-4 recapitulates pituitary tumorigenesis

http://www.wikidata.org/entity/Q28344662

description

2002 nî lūn-bûn

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Targeted expression of a human ...... ulates pituitary tumorigenesis

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Targeted expression of a human ...... ulates pituitary tumorigenesis

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Targeted expression of a human ...... ulates pituitary tumorigenesis

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Targeted expression of a human ...... ulates pituitary tumorigenesis

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Targeted expression of a human ...... ulates pituitary tumorigenesis

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Targeted expression of a human ...... ulates pituitary tumorigenesis

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Targeted expression of a human ...... ulates pituitary tumorigenesis

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Targeted expression of a human ...... ulates pituitary tumorigenesis

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Targeted expression of a human ...... ulates pituitary tumorigenesis

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Targeted expression of a human ...... ulates pituitary tumorigenesis

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Gillian E Wu

http://www.w3.org/2001/XMLSchema#string

Lei Zheng

http://www.w3.org/2001/XMLSchema#string

Sylvia L Asa

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Xian-Feng Zhu

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P2860

FGF-19, a novel fibroblast growth factor with unique specificity for FGFR4

Receptor specificity of the fibroblast growth factor family

Mutations of the MEN1 tumor suppressor gene in pituitary tumors

Pituitary lactotroph adenomas develop after prolonged lactotroph hyperplasia in dopamine D2 receptor-deficient mice

Pituitary lactotroph hyperplasia and chronic hyperprolactinemia in dopamine D2 receptor-deficient mice

Mice lacking p27(Kip1) display increased body size, multiple organ hyperplasia, retinal dysplasia, and pituitary tumors

Effects of an Rb mutation in the mouse

Genomic structure and complete sequence of the human FGFR4 gene.

Enhanced growth of mice lacking the cyclin-dependent kinase inhibitor function of p27(Kip1).

A syndrome of multiorgan hyperplasia with features of gigantism, tumorigenesis, and female sterility in p27(Kip1)-deficient mice.

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