Pyrrolo[2,3-d]pyrimidine nucleosides as inhibitors of human cytomegalovirus
about
Comparison of in vitro biological properties and mouse toxicities of three thymidine analogs active against human immunodeficiency virusNonnucleoside pyrrolopyrimidines with a unique mechanism of action against human cytomegalovirusPhosphorylation of beta-D-ribosylbenzimidazoles is not required for activity against human cytomegalovirus(S)-1-(3-hydroxy-2-phosphonylmethoxypropyl)cytosine, a potent and selective inhibitor of human cytomegalovirus replicationInhibition of human cytomegalovirus in culture by alkenyl guanine analogs of the thiazolo[4,5-d]pyrimidine ring systemDesign, synthesis, and antiviral evaluation of 2-deoxy-D-ribosides of substituted benzimidazoles as potential agents for human cytomegalovirus infectionsResistance of human cytomegalovirus to benzimidazole ribonucleosides maps to two open reading frames: UL89 and UL56Resistance of human cytomegalovirus to the benzimidazole L-ribonucleoside maribavir maps to UL27Inhibition of cyclin-dependent kinase 1 by purines and pyrrolo[2,3-d]pyrimidines does not correlate with antiviral activitySynthesis of a 6-methyl-7-deaza analogue of adenosine that potently inhibits replication of polio and dengue virusesTyrosine-based 1-(S)-[3-hydroxy-2-(phosphonomethoxy)propyl]cytosine and -adenine ((S)-HPMPC and (S)-HPMPA) prodrugs: synthesis, stability, antiviral activity, and in vivo transport studiesTopical delivery of liposomally encapsulated interferon evaluated in a cutaneous herpes guinea pig model.Acquisition of cytomegalovirus infection: an update.Role of a mutation in human cytomegalovirus gene UL104 in resistance to benzimidazole ribonucleosides.Serine peptide phosphoester prodrugs of cyclic cidofovir: synthesis, transport, and antiviral activityInhibition of human cytomegalovirus replication by benzimidazole nucleosides involves three distinct mechanisms.Synthesis of purine and 7-deazapurine nucleoside analogues of 6-N-(4-Nitrobenzyl)adenosine; inhibition of nucleoside transport and proliferation of cancer cells.The human cytomegalovirus UL97 protein kinase, an antiviral drug target, is required at the stage of nuclear egressThe human cytomegalovirus UL44 protein is a substrate for the UL97 protein kinase.Antagonism of the cytotoxic but not antiviral effects of ara-sangivamycin by adenosine.The nucleoside analog sangivamycin induces apoptotic cell death in breast carcinoma MCF7/adriamycin-resistant cells via protein kinase Cdelta and JNK activation.Synthesis and antiviral activity of some 2-substituted 3-formyl- and 3-cyano-5,6-dichloroindole nucleosides.Design, synthesis, and antiviral evaluation of some polyhalogenated indole C-nucleosides.Synthesis and antiviral evaluation of some novel tricyclic pyrazolo[3,4-b]indole nucleosides.Synthesis and antiviral activity of 2-substituted analogs of triciribine.Design and synthesis of acyclic nucleoside analogs with chlorinated imidazo[1,2-a]pyridine bases.Flow cytometric evaluation of the cytotoxicity of novel antiviral compounds.Synthesis of 3-aminoimidazo[4,5-c]pyrazole nucleoside via the N-N bond formation strategy as a [5:5] fused analog of adenosine.Inhibition of cell growth and DNA, RNA, and protein synthesis in vitro by fentanyl, sufentanil, and opiate analgesics.
P2860
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P2860
Pyrrolo[2,3-d]pyrimidine nucleosides as inhibitors of human cytomegalovirus
description
1987 nî lūn-bûn
@nan
1987 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
1987 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
1987年の論文
@ja
1987年論文
@yue
1987年論文
@zh-hant
1987年論文
@zh-hk
1987年論文
@zh-mo
1987年論文
@zh-tw
1987年论文
@wuu
name
Pyrrolo[2,3-d]pyrimidine nucleosides as inhibitors of human cytomegalovirus
@ast
Pyrrolo[2,3-d]pyrimidine nucleosides as inhibitors of human cytomegalovirus
@en
Pyrrolo[2,3-d]pyrimidine nucleosides as inhibitors of human cytomegalovirus
@nl
type
label
Pyrrolo[2,3-d]pyrimidine nucleosides as inhibitors of human cytomegalovirus
@ast
Pyrrolo[2,3-d]pyrimidine nucleosides as inhibitors of human cytomegalovirus
@en
Pyrrolo[2,3-d]pyrimidine nucleosides as inhibitors of human cytomegalovirus
@nl
prefLabel
Pyrrolo[2,3-d]pyrimidine nucleosides as inhibitors of human cytomegalovirus
@ast
Pyrrolo[2,3-d]pyrimidine nucleosides as inhibitors of human cytomegalovirus
@en
Pyrrolo[2,3-d]pyrimidine nucleosides as inhibitors of human cytomegalovirus
@nl
P2093
P2860
P356
P1476
Pyrrolo[2,3-d]pyrimidine nucleosides as inhibitors of human cytomegalovirus
@en
P2093
G Genzlinger
L B Townsend
S H Krawczyk
P2860
P304
P356
10.1128/AAC.31.4.544
P407
P577
1987-04-01T00:00:00Z