Role of a mutation in human cytomegalovirus gene UL104 in resistance to benzimidazole ribonucleosides.
about
Letermovir and inhibitors of the terminase complex: a promising new class of investigational antiviral drugs against human cytomegalovirusAntiviral drug resistance of human cytomegalovirus.Human cytomegalovirus resistance to deoxyribosylindole nucleosides maps to a transversion mutation in the terminase subunit-encoding gene UL89.Progress in the development of new therapies for herpesvirus infectionsIntermolecular Complementation between Two Varicella-Zoster Virus pORF30 Terminase Domains Essential for DNA Encapsidation.The human cytomegalovirus UL51 protein is essential for viral genome cleavage-packaging and interacts with the terminase subunits pUL56 and pUL89.The search for new therapies for human cytomegalovirus infections.The novel anticytomegalovirus compound AIC246 (Letermovir) inhibits human cytomegalovirus replication through a specific antiviral mechanism that involves the viral terminase.Interaction of the putative human cytomegalovirus portal protein pUL104 with the large terminase subunit pUL56 and its inhibition by benzimidazole-D-ribonucleosides.Benzimidazole analogs inhibit human herpesvirus 6.
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Role of a mutation in human cytomegalovirus gene UL104 in resistance to benzimidazole ribonucleosides.
description
2004 nî lūn-bûn
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2004年の論文
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2004年論文
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2004年論文
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2004年論文
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2004年論文
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2004年論文
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2004年论文
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name
Role of a mutation in human cy ...... benzimidazole ribonucleosides.
@en
type
label
Role of a mutation in human cy ...... benzimidazole ribonucleosides.
@en
prefLabel
Role of a mutation in human cy ...... benzimidazole ribonucleosides.
@en
P2093
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Role of a mutation in human cy ...... benzimidazole ribonucleosides.
@en
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Gloria Komazin
John C Drach
Leroy B Townsend
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10.1128/JVI.78.2.710-715.2004
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2004-01-01T00:00:00Z