Synthesis and properties of mRNAs containing the novel "anti-reverse" cap analogs 7-methyl(3'-O-methyl)GpppG and 7-methyl (3'-deoxy)GpppG
about
Nematode m7GpppG and m3(2,2,7)GpppG decapping: activities in Ascaris embryos and characterization of C. elegans scavenger DcpSRNA-Based Vaccines in Cancer ImmunotherapyA high throughput microelectroporation device to introduce a chimeric antigen receptor to redirect the specificity of human T cells.Chemical synthesis and binding activity of the trypanosomatid cap-4 structure.Quantitative effect of suboptimal codon usage on translational efficiency of mRNA encoding HIV-1 gag in intact T cells.Ectopic expression of a truncated CD40L protein from synthetic post-transcriptionally capped RNA in dendritic cells induces high levels of IL-12 secretion.Applications of Phosphate Modification and Labeling to Study (m)RNA Caps.Translation of Angiotensin-Converting Enzyme 2 upon Liver- and Lung-Targeted Delivery of Optimized Chemically Modified mRNAThe notorious R.N.A. in the spotlight - drug or target for the treatment of diseaseStructural requirements for Caenorhabditis elegans DcpS substrates based on fluorescence and HPLC enzyme kinetic studies.Towards mRNA with superior translational activity: synthesis and properties of ARCA tetraphosphates with single phosphorothioate modifications.Triazole-containing monophosphate mRNA cap analogs as effective translation inhibitorsSynthesis, properties, and biological activity of boranophosphate analogs of the mRNA cap: versatile tools for manipulation of therapeutically relevant cap-dependent processes.Novel "anti-reverse" cap analogs with superior translational propertiesNovel cap analogs for in vitro synthesis of mRNAs with high translational efficiency.The antiviral drug ribavirin does not mimic the 7-methylguanosine moiety of the mRNA cap structure in vitro.Functional coupling of RNAP II transcription to spliceosome assemblyTranslation, stability, and resistance to decapping of mRNAs containing caps substituted in the triphosphate chain with BH3, Se, and NHCDK1 substitutes for mTOR kinase to activate mitotic cap-dependent protein translationChallenging the Roles of NSP3 and Untranslated Regions in Rotavirus mRNA Translation.Two-headed tetraphosphate cap analogs are inhibitors of the Dcp1/2 RNA decapping complex.Phosphorothioate cap analogs stabilize mRNA and increase translational efficiency in mammalian cells.Affinity resins containing enzymatically resistant mRNA cap analogs--a new tool for the analysis of cap-binding proteins.Biomaterials for mRNA delivery.Bluetongue virus non-structural protein 1 is a positive regulator of viral protein synthesisA novel route for preparing 5' cap mimics and capped RNAs: phosphate-modified cap analogues obtained via click chemistryModified mRNA as an alternative to plasmid DNA (pDNA) for transcript replacement and vaccination therapy.mRNAs containing the histone 3' stem-loop are degraded primarily by decapping mediated by oligouridylation of the 3' end.Inhibition of Mitogen-activated Protein Kinase (MAPK)-interacting Kinase (MNK) Preferentially Affects Translation of mRNAs Containing Both a 5'-Terminal Cap and Hairpin.Synthesis and characterization of mRNA cap analogs containing phosphorothioate substitutions that bind tightly to eIF4E and are resistant to the decapping pyrophosphatase DcpSDeveloping mRNA-vaccine technologies.Synthesis and evaluation of fluorescent cap analogues for mRNA labelling.Cap analogs modified with 1,2-dithiodiphosphate moiety protect mRNA from decapping and enhance its translational potential.The application of mRNA-based gene transfer in mesenchymal stem cell-mediated cytotoxicity of glioma cells.In vitro transcription and capping of Gaussia luciferase mRNA followed by HeLa cell transfectionTranslation, but not transfection limits clinically relevant, exogenous mRNA based induction of alpha-4 integrin expression on human mesenchymal stem cells.Adipose‑derived mesenchymal stem cell‑facilitated TRAIL expression in melanoma treatment in vitro.Viral and Synthetic RNA Vector Technologies and Applications.Evaluation of RNA Amplification Methods to Improve DC Immunotherapy Antigen Presentation and Immune ResponseCationic Nanoliposomes Meet mRNA: Efficient Delivery of Modified mRNA Using Hemocompatible and Stable Vectors for Therapeutic Applications.
P2860
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P2860
Synthesis and properties of mRNAs containing the novel "anti-reverse" cap analogs 7-methyl(3'-O-methyl)GpppG and 7-methyl (3'-deoxy)GpppG
description
2001 nî lūn-bûn
@nan
2001 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2001 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
2001年の論文
@ja
2001年論文
@yue
2001年論文
@zh-hant
2001年論文
@zh-hk
2001年論文
@zh-mo
2001年論文
@zh-tw
2001年论文
@wuu
name
Synthesis and properties of mR ...... G and 7-methyl (3'-deoxy)GpppG
@ast
Synthesis and properties of mR ...... G and 7-methyl (3'-deoxy)GpppG
@en
Synthesis and properties of mR ...... G and 7-methyl (3'-deoxy)GpppG
@nl
type
label
Synthesis and properties of mR ...... G and 7-methyl (3'-deoxy)GpppG
@ast
Synthesis and properties of mR ...... G and 7-methyl (3'-deoxy)GpppG
@en
Synthesis and properties of mR ...... G and 7-methyl (3'-deoxy)GpppG
@nl
prefLabel
Synthesis and properties of mR ...... G and 7-methyl (3'-deoxy)GpppG
@ast
Synthesis and properties of mR ...... G and 7-methyl (3'-deoxy)GpppG
@en
Synthesis and properties of mR ...... G and 7-methyl (3'-deoxy)GpppG
@nl
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P2860
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P1476
Synthesis and properties of mR ...... G and 7-methyl (3'-deoxy)GpppG
@en
P2093
E Darzynkiewicz
J Stepinski
R E Rhoads
R Stolarski
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2001-10-01T00:00:00Z