Loss of haem in rat liver caused by the porphyrogenic agent 2-allyl-2-isopropylacetamide
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Degradation of cytochrome P-450 haem by carbon tetrachloride and 2-allyl-2-isopropylacetamide in rat liver in vivo and in vitro. Involvement of non-carbon monoxide-forming mechanismsStudies on the mechanism of experimental porphyria produced by 3,5-diethoxycarbonyl-1,4-dihydrocollidine. Role of a porphyrin-like inhibitor of protohaem ferro-lyaseMetabolic activation of acetylenic substituents to derivatives in the rat causing the loss of hepatic cytochrome P-450 and haemLoss of haem from cytochrome P-450 caused by lipid peroxidation and 2-allyl-2-isoprophylacetamide. An abnormal pathway not involving production of carbon monoxideDecreased liver cytochrome P-450 in rats caused by norethindrone or ethynyloestradiolEffect of 2-allyl-2-isopropylacetamide on poly(adenylic acid)-containing ribonucleic acidEffect of allylisopropylacetamide on Nuclear Ribonucleic Acid synthesis in rat liverDifferential haemin-mediated restoration of cytochrome P-450 N-demethylases after inactivation by allylisopropylacetamideBiochemical effects of the porphyrinogenic drug allylisopropylacetamide. A comparative study with phenobarbitalThe effect of exogenous -aminolaevulinate on rat liver haem and cytochromesThe effects of drugs on the activities of 5-aminolaevulinate synthetase and other enzymes in the pathway of haem biosynthesisDecreased liver activity of porphyrin-metal chelatase in hepatic porphyria caused by 3,5-diethoxycarbonyl-1,4-dihydrocollidine. Studies in rats and miceA model for the regulation of delta-aminolaevulinate synthetase induction in rat liverThe effects of chemical porphyrogens and drugs on the activity of rat liver tryptophan pyrrolaseThe effect of fluroxene [(2,2,2-trifluoroethoxy)ethane] on haem biosynthesis and degradationEffect of allylisopropylacetamide on glutathione metabolism in the rat liver. The possible role of glutathione in the induction of 5-aminolaevulinate synthaseTryptophan pyrrolase in haem regulation. The relationship between the depletion of rat liver tryptophan pyrrolase haem and the enhancement of 5-aminolaevulinate synthase activity by 2-allyl-2-isopropylacetamideFormation of cytochrome P-450 containing haem or cobalt-protoporphyrin in liver homogenates of rats treated with phenobarbital and allylisopropylacetamideTryptophan pyrrolase in haem regulation. The mechanism of the permissive effect of cortisol on the enhancement of 5-aminolaevulinate synthase activity by 2-allyl-2-isopropylacetamide in the adrenalectomized-rat liverMetabolism of hepatic haem and 'green pigments' in rats given 2-allyl-2-isopropylacetamide and ferric citrate. A new model for hepatic haem turnoverDifferential responses to inducers of delta-aminolaevulinate synthase and haem oxygenase during pregnancyHepatic drug metabolism and haem biosynthesis in lead-poisoned ratsOccurrence and biological properties of N-methyl protoporphyrin.Formation of cobalt protoporphyrin in the liver of rats. A mechanism for the inhibition of liver haem biosynthesis by inorganic cobalt.Stimulation of liver 5-aminolaevulinate synthetase by drugs and its relevance to drug-induced accumulation of cytochrome P-450. Studies with phenylbutazone and 3,5-diethoxycarbonyl-1,4-dihydrocollidine.Inhibition of haem synthesis caused by cobalt in rat liver. Evidence for two different sites of action.Mammalian epoxide hydrases: inducible enzymes catalysing the inactivation of carcinogenic and cytotoxic metabolites derived from aromatic and olefinic compounds.Cytochrome P450 regulation: the interplay between its heme and apoprotein moieties in synthesis, assembly, repair, and disposal.NO., CO and .OH. Endogenous soluble guanylyl cyclase-activating factors.Epoxidation of olefins by cytochrome P-450 model compounds: mechanism of oxygen atom transfer.Properties of 5-aminolaevulinate synthetase and its relationship to microsomal mixed-function oxidation in the southern armyworm (Spodoptera eridania).Alteration of the porphyrin nucleus of cytochrome P-450 caused in the liver by treatment with allyl-containing drugs. Is the modified porphyrin N-substituted?Tryptophan pyrrolase in haem regulation. Experiments with administered haematin and the relationship between the haem saturation of tryptophan pyrrolase and the activity of 5-aminolaevulinate synthase in rat liverThe role of cytosolic proteins in the intracellular transport of haem in rat liver. A dual-label approach.Destruction of liver haem by norethindrone. Conversion into green pigments.Evidence for the in vitro metabolism of allylisopropylacetamide to reactive intermediates. Mechanistic studies with oxygen-18.Influence of allylisopropylacetamide and phenobarbital treatment on in vivo antipyrine metabolite formation in rats.Evidence that 2-allyl-2-isopropylacetamide, phenobarbital and 3,5-diethoxycarbonyl-1,4-dihydrocollidine induce the same cytochrome P450 mRNA in chick embryo liver.Inhibition of mixed-function oxidase activities in vitro and in vivo: comparisons between kidney and liver.Regulation of rat liver tryptophan pyrrolase by its cofactor haem: Experiments with haematin and 5-aminolaevulinate and comparison with the substrate and hormonal mechanisms.
P2860
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P2860
Loss of haem in rat liver caused by the porphyrogenic agent 2-allyl-2-isopropylacetamide
description
1971 nî lūn-bûn
@nan
1971 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
1971 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
1971年の論文
@ja
1971年論文
@yue
1971年論文
@zh-hant
1971年論文
@zh-hk
1971年論文
@zh-mo
1971年論文
@zh-tw
1971年论文
@wuu
name
Loss of haem in rat liver caused by the porphyrogenic agent 2-allyl-2-isopropylacetamide
@ast
Loss of haem in rat liver caused by the porphyrogenic agent 2-allyl-2-isopropylacetamide
@en
Loss of haem in rat liver caused by the porphyrogenic agent 2-allyl-2-isopropylacetamide
@nl
type
label
Loss of haem in rat liver caused by the porphyrogenic agent 2-allyl-2-isopropylacetamide
@ast
Loss of haem in rat liver caused by the porphyrogenic agent 2-allyl-2-isopropylacetamide
@en
Loss of haem in rat liver caused by the porphyrogenic agent 2-allyl-2-isopropylacetamide
@nl
prefLabel
Loss of haem in rat liver caused by the porphyrogenic agent 2-allyl-2-isopropylacetamide
@ast
Loss of haem in rat liver caused by the porphyrogenic agent 2-allyl-2-isopropylacetamide
@en
Loss of haem in rat liver caused by the porphyrogenic agent 2-allyl-2-isopropylacetamide
@nl
P2860
P356
P1433
P1476
Loss of haem in rat liver caused by the porphyrogenic agent 2-allyl-2-isopropylacetamide
@en
P2093
F De Matteis
P2860
P304
P356
10.1042/BJ1240767
P407
P577
1971-10-01T00:00:00Z