The internal pH and membrane potential of the insulin-secretory granule
about
Sortilin controls intracellular sorting of brain-derived neurotrophic factor to the regulated secretory pathway.Inhibition of IAPP Aggregation and Toxicity by Natural Products and DerivativesStructure and membrane orientation of IAPP in its natively amidated form at physiological pH in a membrane environmentProteolytic processing of chromogranin A in purified insulin granules. Formation of a 20 kDa N-terminal fragment (betagranin) by the concerted action of a Ca2+-dependent endopeptidase and carboxypeptidase H (EC 3.4.17.10)The insulin-secretory-granule carboxypeptidase H. Purification and demonstration of involvement in proinsulin processingMonitoring of exocytosis and endocytosis of insulin secretory granules in the pancreatic beta-cell line MIN6 using pH-sensitive green fluorescent protein (pHluorin) and confocal laser microscopyProinsulin is refractory to protein fibrillation: topological protection of a precursor protein from cross-beta assembly.Imaging a target of Ca2+ signalling: dense core granule exocytosis viewed by total internal reflection fluorescence microscopy.A Molecular Level Understanding of Zinc Activation of C-peptide and its Effects on Cellular Communication in the Bloodstream.Biochemical and cell biological properties of the human prohormone convertase 1/3 Ser357Gly mutation: a PC1/3 hypermorph.Elemental composition of secretory granules in pancreatic islets of Langerhans.Glucose-induced oscillatory changes in extracellular ionized potassium concentration in mouse islets of Langerhans.Proton transport and cell function.A Far-Red Emitting Probe for Unambiguous Detection of Mobile Zinc in Acidic Vesicles and Deep Tissue.Evolution of the voltage sensor domain of the voltage-sensitive phosphoinositide phosphatase VSP/TPTE suggests a role as a proton channel in eutherian mammalsAssociation of newly synthesized islet prohormones with intracellular membranes.Regulation of cell pH by Ca+2-mediated exocytotic insertion of H+-ATPases.Conversion of proinsulin to insulin occurs coordinately with acidification of maturing secretory vesiclesA view of acidic intracellular compartments.Islet Amyloid Polypeptide: Structure, Function, and Pathophysiology.Dense-core secretory granule biogenesis.Visualizing form and function in organotypic slices of the adult mouse parotid gland.Islet amyloid: from fundamental biophysics to mechanisms of cytotoxicity.The granular chloride channel ClC-3 is permissive for insulin secretion.The insulin factory: a tour of the plant surroundings and a visit to the assembly line. The Minkowski lecture 1973 revisited.Implications of peptide assemblies in amyloid diseases.Proton pumps and chemiosmotic coupling as a generalized mechanism for neurotransmitter and hormone transport.Regulation of intracellular pH in eukaryotic cells.The morphology of proinsulin processing.Genetically encoded FRET sensors to monitor intracellular Zn2+ homeostasis.Isolation of dense core secretory vesicles from pancreatic endocrine cells by differential and density gradient centrifugation.Kinetic aspects of compartmental storage and secretion of insulin and zinc.A molecular description of nerve terminal function.Secretory granules.Sorting and processing of secretory proteins.Measurement of secretory vesicle pH reveals intravesicular alkalinization by vesicular monoamine transporter type 2 resulting in inhibition of prohormone cleavage.Biologically active recombinant human progastrin(6-80) contains a tightly bound calcium ion.pH-dependent processing of secretogranin II by the endopeptidase PC2 in isolated immature secretory granules.Glutamate uptake into synaptic vesicles of bovine cerebral cortex and electrochemical potential difference of proton across the membrane.Low-molecular-weight constituents of isolated insulin-secretory granules. Bivalent cations, adenine nucleotides and inorganic phosphate.
P2860
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P2860
The internal pH and membrane potential of the insulin-secretory granule
description
1982 nî lūn-bûn
@nan
1982 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
1982 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
1982年の論文
@ja
1982年論文
@yue
1982年論文
@zh-hant
1982年論文
@zh-hk
1982年論文
@zh-mo
1982年論文
@zh-tw
1982年论文
@wuu
name
The internal pH and membrane potential of the insulin-secretory granule
@ast
The internal pH and membrane potential of the insulin-secretory granule
@en
The internal pH and membrane potential of the insulin-secretory granule
@nl
type
label
The internal pH and membrane potential of the insulin-secretory granule
@ast
The internal pH and membrane potential of the insulin-secretory granule
@en
The internal pH and membrane potential of the insulin-secretory granule
@nl
prefLabel
The internal pH and membrane potential of the insulin-secretory granule
@ast
The internal pH and membrane potential of the insulin-secretory granule
@en
The internal pH and membrane potential of the insulin-secretory granule
@nl
P2860
P356
P1433
P1476
The internal pH and membrane potential of the insulin-secretory granule
@en
P2093
J C Hutton
P2860
P356
10.1042/BJ2040171
P407
P577
1982-04-15T00:00:00Z