Mechanism of inhibition of herpes simplex virus and vaccinia virus DNA polymerases by aphidicolin, a highly specific inhibitor of DNA replication in eucaryotes
about
Effect of aphidicolin on vaccinia virus: isolation of an aphidicolin-resistant mutantIdentification of amino acids in herpes simplex virus DNA polymerase involved in substrate and drug recognition.Structural basis for inhibition of DNA replication by aphidicolinAnalysis of inhibitors of bacteriophage T4 DNA polymerase.Inhibition of herpes simplex virus type 2 growth by phosphorothioate oligodeoxynucleotides.Herpes simplex virus ribonucleotide reductase mutants are hypersensitive to acyclovir.In vitro conversion of MVM parvovirus single-stranded DNA to the replicative form by DNA polymerase alpha from Ehrlich ascites tumour cellsIncorporation of 1-beta-D-arabinofuranosylcytosine into DNA and mutagenesis of herpes simplex virus type 1.An autoradiographic demonstration of nuclear DNA replication by DNA polymerase alpha and of mitochondrial DNA synthesis by DNA polymerase gamma.Characterization of the effect of aphidicolin on adenovirus DNA replication: evidence in support of a protein primer model of initiationSusceptibility of vaccine strains of varicella-zoster virus to antiviral compoundsInhibition of DNA polymerase alpha by aphidicolin derivatives.Betalactam antibiotics interfere with eukaryotic DNA-replication by inhibiting DNA polymerase alpha.Aphidicolin inhibits growth and DNA synthesis in halophilic arachaebacteria.The Dynamics and Regulatory Mechanism of Pronuclear H3k9me2 Asymmetry in Mouse ZygotesGenetic characterization of the vaccinia virus DNA polymerase: cytosine arabinoside resistance requires a variable lesion conferring phosphonoacetate resistance in conjunction with an invariant mutation localized to the 3'-5' exonuclease domain.Unusual regulation of expression of the herpes simplex virus DNA polymerase geneGenetic characterization of the vaccinia virus DNA polymerase: identification of point mutations conferring altered drug sensitivities and reduced fidelity.Engineered herpes simplex virus DNA polymerase point mutants: the most highly conserved region shared among alpha-like DNA polymerases is involved in substrate recognition.Involvement of DNA polymerase alpha in host cell reactivation of UV-irradiated herpes simplex virusStudies with aphidicolin on the Fv-1 host restriction of Friend murine leukemia virus.Sequence and mapping analyses of the herpes simplex virus DNA polymerase gene predict a C-terminal substrate binding domain.Reduced in vivo mutagenesis by mutant herpes simplex DNA polymerase involves improved nucleotide selection.The vaccinia virus DNA polymerase and its processivity factor.Mutually exclusive inhibition of herpesvirus DNA polymerase by aphidicolin, phosphonoformate, and acyclic nucleoside triphosphates.A single-base change within the DNA polymerase locus of herpes simplex virus type 2 can confer resistance to aphidicolin.Compounds that target host cell proteins prevent varicella-zoster virus replication in culture, ex vivo, and in SCID-Hu miceMutations in the herpes simplex virus DNA polymerase gene conferring hypersensitivity to aphidicolin.Aphidicolin inhibits DNA synthesis by DNA polymerase alpha and isolated nuclei by a similar mechanism.Susceptibility of phosphonoformic acid-resistant herpes simplex virus variants to arabinosylnucleosides and aphidicolin.
P2860
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P2860
Mechanism of inhibition of herpes simplex virus and vaccinia virus DNA polymerases by aphidicolin, a highly specific inhibitor of DNA replication in eucaryotes
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1980 nî lūn-bûn
@nan
1980 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
1980 թվականի նոյեմբերին հրատարակված գիտական հոդված
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1980年の論文
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1980年論文
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1980年論文
@zh-hant
1980年論文
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1980年論文
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1980年論文
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1980年论文
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Mechanism of inhibition of her ...... DNA replication in eucaryotes
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Mechanism of inhibition of her ...... DNA replication in eucaryotes
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Mechanism of inhibition of her ...... DNA replication in eucaryotes
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Mechanism of inhibition of her ...... DNA replication in eucaryotes
@ast
Mechanism of inhibition of her ...... DNA replication in eucaryotes
@en
Mechanism of inhibition of her ...... DNA replication in eucaryotes
@nl
prefLabel
Mechanism of inhibition of her ...... DNA replication in eucaryotes
@ast
Mechanism of inhibition of her ...... DNA replication in eucaryotes
@en
Mechanism of inhibition of her ...... DNA replication in eucaryotes
@nl
P2860
P1433
P1476
Mechanism of inhibition of her ...... DNA replication in eucaryotes
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P2093
G Pedrali-Noy
P2860
P304
P407
P577
1980-11-01T00:00:00Z