Geldanamycin induces heat shock protein expression through activation of HSF1 in K562 erythroleukemic cells
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Geldanamycin-induced osteosarcoma cell death is associated with hyperacetylation and loss of mitochondrial pool of heat shock protein 60 (hsp60)Altered chromatin architecture underlies progressive impairment of the heat shock response in mouse models of Huntington disease.Phase I study of 17-allylamino-17 demethoxygeldanamycin, gemcitabine and/or cisplatin in patients with refractory solid tumorsTo fold or not to fold: modulation and consequences of Hsp90 inhibition.Small molecule inhibitor screening identifified HSP90 inhibitor 17-AAG as potential therapeutic agent for gallbladder cancer.Contesting the dogma of an age-related heat shock response impairment: implications for cardiac-specific age-related disorders.Downregulation of the Hsp90 system causes defects in muscle cells of Caenorhabditis elegansInhibition of heat shock protein 90 alleviates steatosis and macrophage activation in murine alcoholic liver injury.O-GlcNAcase Expression is Sensitive to Changes in O-GlcNAc Homeostasis.Pharmacological induction of the heat shock response improves myelination in a neuropathic modelHeat shock proteins as emerging therapeutic targets.Small-Molecule-Mediated Degradation of the Androgen Receptor through Hydrophobic TaggingInhibition of heat shock protein (molecular weight 90 kDa) attenuates proinflammatory cytokines and prevents lipopolysaccharide-induced liver injury in mice.Systematic identification of the HSP90 candidate regulated proteome.HSP90 inhibitor 17-AAG selectively eradicates lymphoma stem cells.Cisplatin abrogates the geldanamycin-induced heat shock responsePhase II trial of gemcitabine and tanespimycin (17AAG) in metastatic pancreatic cancer: a Mayo Clinic Phase II Consortium study.Natural product inhibitors of Hsp90: potential leads for drug discoveryP-Glycoprotein-mediated resistance to Hsp90-directed therapy is eclipsed by the heat shock response.Novobiocin and additional inhibitors of the Hsp90 C-terminal nucleotide-binding pocket.Chronic treatment with 17-DMAG improves balance and coordination in a new mouse model of Machado-Joseph disease.Heat Shock Protein 90 Modulates Lipid Homeostasis by Regulating the Stability and Function of Sterol Regulatory Element-binding Protein (SREBP) and SREBP Cleavage-activating Protein.Alternative approaches to Hsp90 modulation for the treatment of cancer.The anticancer drug AUY922 generates a proteomics fingerprint that is highly conserved among structurally diverse Hsp90 inhibitors.Heat shock protein 90 is a potential therapeutic target for ameliorating skeletal muscle abnormalities in Parkinson's diseaseFibronectin is a stress responsive gene regulated by HSF1 in response to geldanamycin.Investigation of quercetin and hyperoside as senolytics in adult human endothelial cells.Cucurbitacin D Is a Disruptor of the HSP90 Chaperone Machinery.Identification of novel response and predictive biomarkers to Hsp90 inhibitors through mass spectrometry-based proteomic profiling of patient-derived prostate tumor explants.
P2860
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P2860
Geldanamycin induces heat shock protein expression through activation of HSF1 in K562 erythroleukemic cells
description
1999 nî lūn-bûn
@nan
1999 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
1999 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
1999年の論文
@ja
1999年論文
@yue
1999年論文
@zh-hant
1999年論文
@zh-hk
1999年論文
@zh-mo
1999年論文
@zh-tw
1999年论文
@wuu
name
Geldanamycin induces heat shoc ...... in K562 erythroleukemic cells
@ast
Geldanamycin induces heat shoc ...... in K562 erythroleukemic cells
@en
Geldanamycin induces heat shoc ...... in K562 erythroleukemic cells
@nl
type
label
Geldanamycin induces heat shoc ...... in K562 erythroleukemic cells
@ast
Geldanamycin induces heat shoc ...... in K562 erythroleukemic cells
@en
Geldanamycin induces heat shoc ...... in K562 erythroleukemic cells
@nl
prefLabel
Geldanamycin induces heat shoc ...... in K562 erythroleukemic cells
@ast
Geldanamycin induces heat shoc ...... in K562 erythroleukemic cells
@en
Geldanamycin induces heat shoc ...... in K562 erythroleukemic cells
@nl
P2093
P356
P1433
P1476
Geldanamycin induces heat shoc ...... in K562 erythroleukemic cells
@en
P2093
P304
P356
10.1080/152165499306829
P407
P577
1999-10-01T00:00:00Z