Specific 5'-GGGA-3'-->5'-GGA-3' mutation of the Apc gene in rat colon tumors induced by 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine
about
Solution structure of the 2-amino-1- methyl-6-phenylimidazo[4,5-b]pyridine C8-deoxyguanosine adduct in duplex DNAGenomic imbalance in rat mammary gland carcinomas induced by 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridineSynthesis and spectroscopic characterization of site-specific 2-amino-1-methyl-6-phenylimidazo.More frequent beta-catenin gene mutations in adenomas than in aberrant crypt foci or adenocarcinomas in the large intestines of 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP)-treated rats.DNA adduct levels and absence of tumors in female rapid and slow acetylator congenic hamsters administered the rat mammary carcinogen 2-amino-1-methyl-6-phenylimidazo[4,5-b] pyridine.Early detection of 2-amino-1-methyl-6-phenylimidazo (4,5-b)pyridine(PhIP)-induced mutations within the Apc gene of rat colon.Use of transgenic and mutant animal models in the study of heterocyclic amine-induced mutagenesis and carcinogenesis.Mouse models of colorectal cancer.DNA adducts of heterocyclic amine food mutagens: implications for mutagenesis and carcinogenesis.Colorectal cancer: molecules and populations.Carcinogenesis in mouse and human cells: parallels and paradoxes.Nutrition and dietary carcinogens.Understanding the interaction between environmental exposures and molecular events in colorectal carcinogenesis.A critical evaluation of the application of biomarkers in epidemiological studies on diet and health.Human exposure to carcinogenic heterocyclic amines and their mutational fingerprints in experimental animals.Heterocyclic aromatic amine metabolism, DNA adduct formation, mutagenesis, and carcinogenesis.Genetic analysis of colon tumors induced by a dietary carcinogen PhIP in CYP1A humanized mice: Identification of mutation of β-catenin/Ctnnb1 as the driver gene for the carcinogenesis.Point: From animal models to prevention of colon cancer. Systematic review of chemoprevention in min mice and choice of the model system.Somatic mutations, acetylator status, and prognosis in colorectal cancerCharacterization of dysplastic aberrant crypt foci in the rat colon induced by 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridineMutations of the Apc gene in experimental colorectal carcinogenesis induced by azoxymethane in F344 rats.Obesity promotes PhIP-induced small intestinal carcinogenesis in hCYP1A-db/db mice: involvement of mutations and DNA hypermethylation of Apc.Mouse models for the study of colon carcinogenesis.Translesional DNA synthesis through a C8-guanyl adduct of 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) in Vitro: REV1 inserts dC opposite the lesion, and DNA polymerase kappa potentially catalyzes extension reaction from the 3'-dC terminusA rat genetic map constructed by representational difference analysis markers with suitability for large-scale typing.Mutational analysis of three tumor suppressor genes in two models of rat hepatocarcinogenesis.The effect of dietary folate on Apc and p53 mutations in the dimethylhydrazine rat model of colorectal cancer.Microsatellite instability and loss of heterozygosity on chromosome 10 in rat mammary tumors induced by 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine.Effects of 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine on intestinal polyp development in Apc delta 716 knockout mice.New insights in the formation of deoxynucleoside adducts with the heterocyclic aromatic amines PhIP and IQ by means of ion trap MSn and accurate mass measurement of fragment ions.Daikenchuto (TU-100) Suppresses Tumor Development in the Azoxymethane and APCmin/+ Mouse Models of Experimental Colon Cancer.Screening of molecular cell targets for carcinogenic heterocyclic aromatic amines by using CALUX® reporter gene assays.Experimental chemical carcinogenesis in the stomach and colon.Development and distribution of 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP)-induced aberrant crypt foci in the rat large intestine.Mutational and DNA binding specificity of the carcinogen 2-amino-3, 8-dimethylimidazo[4,5-f]quinoxaline.
P2860
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P2860
Specific 5'-GGGA-3'-->5'-GGA-3' mutation of the Apc gene in rat colon tumors induced by 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine
description
1995 nî lūn-bûn
@nan
1995 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
1995 թվականի հունվարին հրատարակված գիտական հոդված
@hy
1995年の論文
@ja
1995年論文
@yue
1995年論文
@zh-hant
1995年論文
@zh-hk
1995年論文
@zh-mo
1995年論文
@zh-tw
1995年论文
@wuu
name
Specific 5'-GGGA-3'-->5'-GGA-3 ...... 6-phenylimidazo[4,5-b]pyridine
@ast
Specific 5'-GGGA-3'-->5'-GGA-3 ...... 6-phenylimidazo[4,5-b]pyridine
@en
Specific 5'-GGGA-3'-->5'-GGA-3 ...... 6-phenylimidazo[4,5-b]pyridine
@nl
type
label
Specific 5'-GGGA-3'-->5'-GGA-3 ...... 6-phenylimidazo[4,5-b]pyridine
@ast
Specific 5'-GGGA-3'-->5'-GGA-3 ...... 6-phenylimidazo[4,5-b]pyridine
@en
Specific 5'-GGGA-3'-->5'-GGA-3 ...... 6-phenylimidazo[4,5-b]pyridine
@nl
prefLabel
Specific 5'-GGGA-3'-->5'-GGA-3 ...... 6-phenylimidazo[4,5-b]pyridine
@ast
Specific 5'-GGGA-3'-->5'-GGA-3 ...... 6-phenylimidazo[4,5-b]pyridine
@en
Specific 5'-GGGA-3'-->5'-GGA-3 ...... 6-phenylimidazo[4,5-b]pyridine
@nl
P2093
P2860
P356
P1476
Specific 5'-GGGA-3'-->5'-GGA-3 ...... 6-phenylimidazo[4,5-b]pyridine
@en
P2093
H Kakiuchi
J H Weisburger
M Watanabe
T Sugimura
T Ushijima
P2860
P356
10.1073/PNAS.92.3.910
P407
P577
1995-01-31T00:00:00Z