Specific 5'-GGGA-3'-->5'-GGA-3' mutation of the Apc gene in rat colon tumors induced by 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine - Wikidata - awgldk - TriplyDB

Specific 5'-GGGA-3'-->5'-GGA-3' mutation of the Apc gene in rat colon tumors induced by 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine

Specific 5'-GGGA-3'-->5'-GGA-3' mutation of the Apc gene in rat colon tumors induced by 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine

http://www.wikidata.org/entity/Q28368405

about

Solution structure of the 2-amino-1- methyl-6-phenylimidazo[4,5-b]pyridine C8-deoxyguanosine adduct in duplex DNA Genomic imbalance in rat mammary gland carcinomas induced by 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine Synthesis and spectroscopic characterization of site-specific 2-amino-1-methyl-6-phenylimidazo.More frequent beta-catenin gene mutations in adenomas than in aberrant crypt foci or adenocarcinomas in the large intestines of 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP)-treated rats.DNA adduct levels and absence of tumors in female rapid and slow acetylator congenic hamsters administered the rat mammary carcinogen 2-amino-1-methyl-6-phenylimidazo[4,5-b] pyridine.Early detection of 2-amino-1-methyl-6-phenylimidazo (4,5-b)pyridine(PhIP)-induced mutations within the Apc gene of rat colon.Use of transgenic and mutant animal models in the study of heterocyclic amine-induced mutagenesis and carcinogenesis.Mouse models of colorectal cancer.DNA adducts of heterocyclic amine food mutagens: implications for mutagenesis and carcinogenesis.Colorectal cancer: molecules and populations.Carcinogenesis in mouse and human cells: parallels and paradoxes.Nutrition and dietary carcinogens.Understanding the interaction between environmental exposures and molecular events in colorectal carcinogenesis.A critical evaluation of the application of biomarkers in epidemiological studies on diet and health.Human exposure to carcinogenic heterocyclic amines and their mutational fingerprints in experimental animals.Heterocyclic aromatic amine metabolism, DNA adduct formation, mutagenesis, and carcinogenesis.Genetic analysis of colon tumors induced by a dietary carcinogen PhIP in CYP1A humanized mice: Identification of mutation of β-catenin/Ctnnb1 as the driver gene for the carcinogenesis.Point: From animal models to prevention of colon cancer. Systematic review of chemoprevention in min mice and choice of the model system.Somatic mutations, acetylator status, and prognosis in colorectal cancer Characterization of dysplastic aberrant crypt foci in the rat colon induced by 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine Mutations of the Apc gene in experimental colorectal carcinogenesis induced by azoxymethane in F344 rats.Obesity promotes PhIP-induced small intestinal carcinogenesis in hCYP1A-db/db mice: involvement of mutations and DNA hypermethylation of Apc.Mouse models for the study of colon carcinogenesis.Translesional DNA synthesis through a C8-guanyl adduct of 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) in Vitro: REV1 inserts dC opposite the lesion, and DNA polymerase kappa potentially catalyzes extension reaction from the 3'-dC terminus A rat genetic map constructed by representational difference analysis markers with suitability for large-scale typing.Mutational analysis of three tumor suppressor genes in two models of rat hepatocarcinogenesis.The effect of dietary folate on Apc and p53 mutations in the dimethylhydrazine rat model of colorectal cancer.Microsatellite instability and loss of heterozygosity on chromosome 10 in rat mammary tumors induced by 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine.Effects of 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine on intestinal polyp development in Apc delta 716 knockout mice.New insights in the formation of deoxynucleoside adducts with the heterocyclic aromatic amines PhIP and IQ by means of ion trap MSn and accurate mass measurement of fragment ions.Daikenchuto (TU-100) Suppresses Tumor Development in the Azoxymethane and APCmin/+ Mouse Models of Experimental Colon Cancer.Screening of molecular cell targets for carcinogenic heterocyclic aromatic amines by using CALUX® reporter gene assays.Experimental chemical carcinogenesis in the stomach and colon.Development and distribution of 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP)-induced aberrant crypt foci in the rat large intestine.Mutational and DNA binding specificity of the carcinogen 2-amino-3, 8-dimethylimidazo[4,5-f]quinoxaline.

P2860

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P2860

Specific 5'-GGGA-3'-->5'-GGA-3' mutation of the Apc gene in rat colon tumors induced by 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine

http://www.wikidata.org/entity/Q28368405

description

1995 nî lūn-bûn

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1995 թուականի Յունուարին հրատարակուած գիտական յօդուած

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1995 թվականի հունվարին հրատարակված գիտական հոդված

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1995年の論文

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1995年論文

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1995年論文

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1995年論文

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1995年論文

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1995年論文

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1995年论文

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name

Specific 5'-GGGA-3'-->5'-GGA-3 ...... 6-phenylimidazo[4,5-b]pyridine

@ast

Specific 5'-GGGA-3'-->5'-GGA-3 ...... 6-phenylimidazo[4,5-b]pyridine

@en

Specific 5'-GGGA-3'-->5'-GGA-3 ...... 6-phenylimidazo[4,5-b]pyridine

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type

label

Specific 5'-GGGA-3'-->5'-GGA-3 ...... 6-phenylimidazo[4,5-b]pyridine

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Specific 5'-GGGA-3'-->5'-GGA-3 ...... 6-phenylimidazo[4,5-b]pyridine

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Specific 5'-GGGA-3'-->5'-GGA-3 ...... 6-phenylimidazo[4,5-b]pyridine

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Specific 5'-GGGA-3'-->5'-GGA-3 ...... 6-phenylimidazo[4,5-b]pyridine

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Specific 5'-GGGA-3'-->5'-GGA-3 ...... 6-phenylimidazo[4,5-b]pyridine

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Specific 5'-GGGA-3'-->5'-GGA-3 ...... 6-phenylimidazo[4,5-b]pyridine

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Proceedings of the National Academy of Sciences of the United States of America

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Specific 5'-GGGA-3'-->5'-GGA-3 ...... 6-phenylimidazo[4,5-b]pyridine

@en

P2093

H Kakiuchi

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J H Weisburger

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K Imai

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M Nagao

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M Toyota

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M Watanabe

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T Sugimura

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T Ushijima

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P2860

Identification of deletion mutations and three new genes at the familial polyposis locus

A genetic model for colorectal tumorigenesis

Detection of polymorphisms of human DNA by gel electrophoresis as single-strand conformation polymorphisms

Genetic changes and histopathological types in colorectal tumors from patients with familial adenomatous polyposis

APC mutations occur early during colorectal tumorigenesis

Genetic alterations during colorectal-tumor development

Identification of FAP locus genes from chromosome 5q21

Multiple intestinal neoplasia caused by a mutation in the murine homolog of the APC gene

Food-derived mutagens and carcinogens.

DNA adduct-induced stabilization of slipped frameshift intermediates within repetitive sequences: implications for mutagenesis.

P304

910-4

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scholarly article

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10.1073/PNAS.92.3.910

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3

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92

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1995-01-31T00:00:00Z

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242906630

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7846077

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42730

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