Mutations of the Apc gene in experimental colorectal carcinogenesis induced by azoxymethane in F344 rats.
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Sulindac and a cyclooxygenase-2 inhibitor, etodolac, increase APC mRNA in the colon of rats treated with azoxymethaneSevere imbalance of cell proliferation and apoptosis in the left colon and in the rectosigmoid tract in subjects with a history of large adenomasAberrant crypt foci in colorectal carcinogenesis. Cell and crypt dynamics.Mouse models of colorectal cancer.Genomic variants in mouse model induced by azoxymethane and dextran sodium sulfate improperly mimic human colorectal cancer.Azoxymethane-induced colon carcinogenesis in mice occurs independently of de novo thymidylate synthesis capacity.Mthfd1 is a modifier of chemically induced intestinal carcinogenesis.Point: From animal models to prevention of colon cancer. Systematic review of chemoprevention in min mice and choice of the model system.Aberrant crypt foci as microscopic precursors of colorectal cancer.CpG island methylation in aberrant crypt foci of the colorectumMolecular mechanism of adenomatous polyposis coli-induced blockade of base excision repair pathway in colorectal carcinogenesis.Overexpression of protein kinase C betaII induces colonic hyperproliferation and increased sensitivity to colon carcinogenesis.APC and K-ras gene mutation in aberrant crypt foci of human colon.Mouse models for the study of colon carcinogenesis.Genetic and epigenetic changes in aberrant crypt foci and serrated polyps.Morphological and molecular alterations in 1,2 dimethylhydrazine and azoxymethane induced colon carcinogenesis in rats.NSAIDs inhibit tumorigenesis, but how?Increased susceptibility of Sf1(+/-) mice to azoxymethane-induced colon tumorigenesis.Carcinogen-induced colon tumors in mice are chromosomally stable and are characterized by low-level microsatellite instability.The effect of dietary folate on Apc and p53 mutations in the dimethylhydrazine rat model of colorectal cancer.Microarray Analyses of Genes Differentially Expressed by Diet (Black Beans and Soy Flour) during Azoxymethane-Induced Colon Carcinogenesis in Rats.Sulindac corrects defective apoptosis and suppresses azoxymethane-induced colonic oncogenesis in p53 knockout mice.Mechanisms and anticarcinogenic effects of diet-related apoptosis in the intestinal mucosa.
P2860
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P2860
Mutations of the Apc gene in experimental colorectal carcinogenesis induced by azoxymethane in F344 rats.
description
1998 nî lūn-bûn
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1998年の論文
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1998年学术文章
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1998年学术文章
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1998年学术文章
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1998年学术文章
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1998年学术文章
@zh-sg
1998年學術文章
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1998年學術文章
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1998年學術文章
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name
Mutations of the Apc gene in e ...... by azoxymethane in F344 rats.
@ast
Mutations of the Apc gene in e ...... by azoxymethane in F344 rats.
@en
type
label
Mutations of the Apc gene in e ...... by azoxymethane in F344 rats.
@ast
Mutations of the Apc gene in e ...... by azoxymethane in F344 rats.
@en
prefLabel
Mutations of the Apc gene in e ...... by azoxymethane in F344 rats.
@ast
Mutations of the Apc gene in e ...... by azoxymethane in F344 rats.
@en
P2093
P2860
P356
P1476
Mutations of the Apc gene in e ...... d by azoxymethane in F344 rats
@en
P2093
P2860
P2888
P304
P356
10.1038/BJC.1998.359
P407
P577
1998-06-01T00:00:00Z