Mode of action of SDZ NIM 811, a nonimmunosuppressive cyclosporin A analog with activity against human immunodeficiency virus (HIV) type 1: interference with HIV protein-cyclophilin A interactions
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Inhibition of HIV-1 multiplication by antisense U7 snRNAs and siRNAs targeting cyclophilin AInhibition of human immunodeficiency virus type 1 replication in human cells by Debio-025, a novel cyclophilin binding agentSuppression of coronavirus replication by cyclophilin inhibitorsCuring a viral infection by targeting the host: the example of cyclophilin inhibitorsNIM811, a Cyclophilin Inhibitor, Exhibits Potent In Vitro Activity against Hepatitis C Virus Alone or in Combination with Alpha InterferonCyclosporine Inhibits Flavivirus Replication through Blocking the Interaction between Host Cyclophilins and Viral NS5 ProteinSCY-635, a Novel Nonimmunosuppressive Analog of Cyclosporine That Exhibits Potent Inhibition of Hepatitis C Virus RNA Replication In VitroCyclophilin catalyzes protein folding in yeast mitochondria.The human immunodeficiency virus type 1 capsid p2 domain confers sensitivity to the cyclophilin-binding drug SDZ NIM 811Cyclophilin A-induced alterations of human immunodeficiency virus type 1 CA protein in vitroRanking high affinity ligands of low solubility by NMR spectroscopySelection of recombinant, library-derived antibody fragments against p24 for human immunodeficiency virus type 1 diagnostics.Heat shock protein-based therapeutic strategies against human immunodeficiency virus type 1 infection.The intriguing cyclophilin A-HIV-1 Vpr interaction: prolyl cis/trans isomerisation catalysis and specific binding.Cells with high cyclophilin A content support replication of human immunodeficiency virus type 1 Gag mutants with decreased ability to incorporate cyclophilin AExtracellular cyclophilins contribute to the regulation of inflammatory responsesChimeric human immunodeficiency virus type 1 virions that contain the simian immunodeficiency virus nef gene are cyclosporin A resistant.The host-pathogen interaction of human cyclophilin A and HIV-1 Vpr requires specific N-terminal and novel C-terminal domainsThe immunosuppressant rapamycin represses human immunodeficiency virus type 1 replicationContribution of glutamine residues in the helix 4-5 loop to capsid-capsid interactions in simian immunodeficiency virus of macaques.trans-Complementation rescue of cyclophilin A-deficient viruses reveals that the requirement for cyclophilin A in human immunodeficiency virus type 1 replication is independent of its isomerase activityKnockdown of the cellular protein LRPPRC attenuates HIV-1 infection.Delaying reverse transcription does not increase sensitivity of HIV-1 to human TRIM5α.Cyclophilin a plays distinct roles in human immunodeficiency virus type 1 entry and postentry events, as revealed by spinoculation.Proteomic profiling of SupT1 cells reveal modulation of host proteins by HIV-1 Nef variantsBlocking cyclophilins in the chronic phase of asthma reduces the persistence of leukocytes and disease reactivation.The TB Structural Genomics Consortium: a decade of progress.Spontaneous mutations in the human immunodeficiency virus type 1 gag gene that affect viral replication in the presence of cyclosporins.Cyclophilin A is required for an early step in the life cycle of human immunodeficiency virus type 1 before the initiation of reverse transcriptionCyclophilin A is required for the replication of group M human immunodeficiency virus type 1 (HIV-1) and simian immunodeficiency virus SIV(CPZ)GAB but not group O HIV-1 or other primate immunodeficiency virusesRole of cyclophilin A in the uptake of HIV-1 by macrophages and T lymphocytes.Active-site residues of cyclophilin A are crucial for its incorporation into human immunodeficiency virus type 1 virions.Analysis of human cell heterokaryons demonstrates that target cell restriction of cyclosporine-resistant human immunodeficiency virus type 1 mutants is genetically dominant.A cell-impermeable cyclosporine A derivative reduces pathology in a mouse model of allergic lung inflammation.Identification of HIV inhibitors guided by free energy perturbation calculations.Peptidyl prolyl cis-trans isomerase activity of cyclophilin A in functional homo-oligomeric receptor expressionNuclear Envelope Protein SUN2 Promotes Cyclophilin-A-Dependent Steps of HIV ReplicationChimeric human immunodeficiency virus type 1 (HIV-1) virions containing HIV-2 or simian immunodeficiency virus Nef are resistant to cyclosporine treatment.Correlation of naturally occurring HIV-1 resistance to DEB025 with capsid amino acid polymorphismsSecreted cyclophilin A, a peptidylprolyl cis-trans isomerase, mediates matrix assembly of hensin, a protein implicated in epithelial differentiation.
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P2860
Mode of action of SDZ NIM 811, a nonimmunosuppressive cyclosporin A analog with activity against human immunodeficiency virus (HIV) type 1: interference with HIV protein-cyclophilin A interactions
description
1995 nî lūn-bûn
@nan
1995 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
1995 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
1995年の論文
@ja
1995年論文
@yue
1995年論文
@zh-hant
1995年論文
@zh-hk
1995年論文
@zh-mo
1995年論文
@zh-tw
1995年论文
@wuu
name
Mode of action of SDZ NIM 811, ...... ein-cyclophilin A interactions
@ast
Mode of action of SDZ NIM 811, ...... ein-cyclophilin A interactions
@en
Mode of action of SDZ NIM 811, ...... ein-cyclophilin A interactions
@nl
type
label
Mode of action of SDZ NIM 811, ...... ein-cyclophilin A interactions
@ast
Mode of action of SDZ NIM 811, ...... ein-cyclophilin A interactions
@en
Mode of action of SDZ NIM 811, ...... ein-cyclophilin A interactions
@nl
prefLabel
Mode of action of SDZ NIM 811, ...... ein-cyclophilin A interactions
@ast
Mode of action of SDZ NIM 811, ...... ein-cyclophilin A interactions
@en
Mode of action of SDZ NIM 811, ...... ein-cyclophilin A interactions
@nl
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Mode of action of SDZ NIM 811, ...... ein-cyclophilin A interactions
@en
P2093
Hammerschmid F
Quesniaux V
Rosenwirth B
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P407
P577
1995-04-01T00:00:00Z