The immunosuppressant rapamycin represses human immunodeficiency virus type 1 replication
about
Potential use of rapamycin in HIV infectionRapamycin blocks production of KSHV/HHV8: insights into the anti-tumor activity of an immunosuppressant drug.Renal transplantation in patients with HIV.HIV-1 promotes renal tubular epithelial cell protein synthesis: role of mTOR pathway.Hormonally active vitamin D3 (1alpha,25-dihydroxycholecalciferol) triggers autophagy in human macrophages that inhibits HIV-1 infection.Rapamycin-induced inhibition of HTLV-I LTR activity is rescued by c-Myb.Rapamycin with antiretroviral therapy in AIDS-associated Kaposi sarcoma: an AIDS Malignancy Consortium study.Rapamycin reduces CCR5 density levels on CD4 T cells, and this effect results in potentiation of enfuvirtide (T-20) against R5 strains of human immunodeficiency virus type 1 in vitro.Targeting of mTOR catalytic site inhibits multiple steps of the HIV-1 lifecycle and suppresses HIV-1 viremia in humanized mice.Rapamycin causes down-regulation of CCR5 and accumulation of anti-HIV beta-chemokines: an approach to suppress R5 strains of HIV-1.Nucleofection induces transient eIF2α phosphorylation by GCN2 and PERK.Sirolimus modulates HIVAN phenotype through inhibition of epithelial mesenchymal transition.Dual role of autophagy in HIV-1 replication and pathogenesisRapamycin-induced modulation of HIV gene transcription attenuates progression of HIVAN.Reduction of CCR5 with low-dose rapamycin enhances the antiviral activity of vicriviroc against both sensitive and drug-resistant HIV-1.Dual inhibition of PI3Kalpha and mTOR as an alternative treatment for Kaposi's sarcoma.Rapamycin-induced modulation of miRNA expression is associated with amelioration of HIV-associated nephropathy (HIVAN).Autophagy pathway intersects with HIV-1 biosynthesis and regulates viral yields in macrophagesEffect of maintenance immunosuppressive drugs on virus pathobiology: evidence and potential mechanisms.Tipping the metabolic scales towards increased longevity in mammals.Broad-spectrum antiviral agents.Can aging be 'drugged'?Inhibition of human immunodeficiency virus (HIV-1) infection in human peripheral blood leucocytes-SCID reconstituted mice by rapamycin.Pharmacological modulation of autophagy: therapeutic potential and persisting obstacles.CD8(+) Lymphocytes Are Required for Maintaining Viral Suppression in SIV-Infected Macaques Treated with Short-Term Antiretroviral Therapy.Exploiting immune cell metabolic machinery for functional HIV cure and the prevention of inflammaging.TSC1 and DEPDC5 regulate HIV-1 latency through the mTOR signaling pathway
P2860
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P2860
The immunosuppressant rapamycin represses human immunodeficiency virus type 1 replication
description
2002 nî lūn-bûn
@nan
2002 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2002 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
2002年の論文
@ja
2002年論文
@yue
2002年論文
@zh-hant
2002年論文
@zh-hk
2002年論文
@zh-mo
2002年論文
@zh-tw
2002年论文
@wuu
name
The immunosuppressant rapamycin represses human immunodeficiency virus type 1 replication
@ast
The immunosuppressant rapamycin represses human immunodeficiency virus type 1 replication
@en
The immunosuppressant rapamycin represses human immunodeficiency virus type 1 replication
@nl
type
label
The immunosuppressant rapamycin represses human immunodeficiency virus type 1 replication
@ast
The immunosuppressant rapamycin represses human immunodeficiency virus type 1 replication
@en
The immunosuppressant rapamycin represses human immunodeficiency virus type 1 replication
@nl
prefLabel
The immunosuppressant rapamycin represses human immunodeficiency virus type 1 replication
@ast
The immunosuppressant rapamycin represses human immunodeficiency virus type 1 replication
@en
The immunosuppressant rapamycin represses human immunodeficiency virus type 1 replication
@nl
P2093
P2860
P1476
The immunosuppressant rapamycin represses human immunodeficiency virus type 1 replication
@en
P2093
Jean-François Fortin
Jean-Sébastien Paquette
Jocelyn Roy
Michel J Tremblay
P2860
P304
P356
10.1128/AAC.46.11.3447-3455.2002
P407
P577
2002-11-01T00:00:00Z