Dexamethasone differentially regulates expression of carboxylesterase genes in humans and rats
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Abundant expression of Dec1/stra13/sharp2 in colon carcinoma: its antagonizing role in serum deprivation-induced apoptosis and selective inhibition of procaspase activationThe use of pharmacokinetic and pharmacodynamic data in the assessment of drug safety in early drug developmentCarboxylesterase-2 is a highly sensitive target of the antiobesity agent orlistat with profound implications in the activation of anticancer prodrugs.Age-related inducibility of carboxylesterases by the antiepileptic agent phenobarbital and implications in drug metabolism and lipid accumulation.Photochemotherapeutic agent 8-methoxypsoralen induces cytochrome P450 3A4 and carboxylesterase HCE2: evidence on an involvement of the pregnane X receptor.Dexamethasone transcriptionally increases the expression of the pregnane X receptor and synergistically enhances pyrethroid esfenvalerate in the induction of cytochrome P450 3A23.In vitro metabolism and drug-drug interaction potential of UTL-5g, a novel chemo- and radioprotective agent.Surge in expression of carboxylesterase 1 during the post-neonatal stage enables a rapid gain of the capacity to activate the anti-influenza prodrug oseltamivir.Significantly reduced cytochrome P450 3A4 expression and activity in liver from humans with diabetes mellitus.Scoparone potentiates transactivation of the bile salt export pump gene and this effect is enhanced by cytochrome P450 metabolism but abolished by a PKC inhibitor.Hypolipidemic agent Z-guggulsterone: metabolism interplays with induction of carboxylesterase and bile salt export pumpEffects of Mitragynine and a Crude Alkaloid Extract Derived from Mitragyna speciosa Korth. on Permethrin Elimination in RatsOntogenic expression of human carboxylesterase-2 and cytochrome P450 3A4 in liver and duodenum: postnatal surge and organ-dependent regulation.Transcription factor-mediated regulation of carboxylesterase enzymes in livers of miceIsoform-Specific Regulation of Mouse Carboxylesterase Expression and Activity by Prototypical Transcriptional Activators.Human carboxylesterases HCE1 and HCE2: ontogenic expression, inter-individual variability and differential hydrolysis of oseltamivir, aspirin, deltamethrin and permethrin.Pyrethroid insecticides: isoform-dependent hydrolysis, induction of cytochrome P450 3A4 and evidence on the involvement of the pregnane X receptor.Nuclear receptor-mediated regulation of carboxylesterase expression and activity.Effects of dexamethasone coadministered with oseltamivir on the pharmacokinetics of oseltamivir in healthy volunteers.Reduced carboxylesterase 1 is associated with endothelial injury in methamphetamine-induced pulmonary arterial hypertension.Regulation of carboxylesterase-2 expression by p53 family proteins and enhanced anti-cancer activities among 5-fluorouracil, irinotecan and doxazolidine prodrug.Antioxidant sulforaphane and sensitizer trinitrobenzene sulfonate induce carboxylesterase-1 through a novel element transactivated by nuclear factor-E2 related factor-2.Dexamethasone suppresses the expression of multiple rat carboxylesterases through transcriptional repression: evidence for an involvement of the glucocorticoid receptor.Organ-specific carboxylesterase profiling identifies the small intestine and kidney as major contributors of activation of the anticancer prodrug CPT-11.Secreted and tumour targeted human carboxylesterase for activation of irinotecanDevelopment of amide-based fluorescent probes for selective measurement of carboxylesterase 1 activity in tissue extracts.Breed Differences in Pig Liver Esterase (PLE) between Tongcheng (Chinese Local Breed) and Large White Pigs
P2860
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P2860
Dexamethasone differentially regulates expression of carboxylesterase genes in humans and rats
description
2000 nî lūn-bûn
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2000 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2000 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2000年の論文
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2000年論文
@yue
2000年論文
@zh-hant
2000年論文
@zh-hk
2000年論文
@zh-mo
2000年論文
@zh-tw
2000年论文
@wuu
name
Dexamethasone differentially r ...... erase genes in humans and rats
@ast
Dexamethasone differentially r ...... erase genes in humans and rats
@en
Dexamethasone differentially r ...... erase genes in humans and rats
@nl
type
label
Dexamethasone differentially r ...... erase genes in humans and rats
@ast
Dexamethasone differentially r ...... erase genes in humans and rats
@en
Dexamethasone differentially r ...... erase genes in humans and rats
@nl
prefLabel
Dexamethasone differentially r ...... erase genes in humans and rats
@ast
Dexamethasone differentially r ...... erase genes in humans and rats
@en
Dexamethasone differentially r ...... erase genes in humans and rats
@nl
P2093
P1476
Dexamethasone differentially r ...... erase genes in humans and rats
@en
P2093
P304
P407
P577
2000-02-01T00:00:00Z