Surge in expression of carboxylesterase 1 during the post-neonatal stage enables a rapid gain of the capacity to activate the anti-influenza prodrug oseltamivir.
about
Inhibition of recombinant human carboxylesterase 1 and 2 and monoacylglycerol lipase by chlorpyrifos oxon, paraoxon and methyl paraoxonCarboxylesterase-2 is a highly sensitive target of the antiobesity agent orlistat with profound implications in the activation of anticancer prodrugs.Age-related inducibility of carboxylesterases by the antiepileptic agent phenobarbital and implications in drug metabolism and lipid accumulation.Suppression of the pregnane X receptor during endoplasmic reticulum stress is achieved by down-regulating hepatocyte nuclear factor-4α and up-regulating liver-enriched inhibitory protein.Hypolipidemic agent Z-guggulsterone: metabolism interplays with induction of carboxylesterase and bile salt export pumpOntogenic expression of human carboxylesterase-2 and cytochrome P450 3A4 in liver and duodenum: postnatal surge and organ-dependent regulation.The role of human carboxylesterases in drug metabolism: have we overlooked their importance?Oseltamivir pharmacokinetics and clinical experience in neonates and infants during an outbreak of H1N1 influenza A virus infection in a neonatal intensive care unitRole of the intestinal peptide transporter PEPT1 in oseltamivir absorption: in vitro and in vivo studies.CES1P1 variant -816A>C is not associated with hepatic carboxylesterase 1 expression and activity or antihypertensive effect of trandolapril.Population pharmacokinetics of oseltamivir: pediatrics through geriatrics.Biocomparison Study of Adult and Paediatric Dose Strengths of the Prostacyclin Receptor Agonist Selexipag.Age-Dependent Absolute Abundance of Hepatic Carboxylesterases (CES1 and CES2) by LC-MS/MS Proteomics: Application to PBPK Modeling of Oseltamivir In Vivo Pharmacokinetics in Infants.Regulation of carboxylesterase-2 expression by p53 family proteins and enhanced anti-cancer activities among 5-fluorouracil, irinotecan and doxazolidine prodrug.Age-Dependent Human Hepatic Carboxylesterase 1 (CES1) and Carboxylesterase 2 (CES2) Postnatal Ontogeny.Gambogic acid potentiates clopidogrel-induced apoptosis and attenuates irinotecan-induced apoptosis through down-regulating human carboxylesterase 1 and -2.Association of Oseltamivir Activation with Gender and Carboxylesterase 1 Genetic Polymorphisms.Effect of carboxylesterase 1 S75N on clopidogrel therapy among acute coronary syndrome patients.Oseltamivir dosing in premature infants.Undesired versus designed enzymatic cleavage of linkers for liver targetingThe posology of oseltamivir in infants with influenza infection using a population pharmacokinetic approach.Development of a physiologically based model for oseltamivir and simulation of pharmacokinetics in neonates and infants.Breed Differences in Pig Liver Esterase (PLE) between Tongcheng (Chinese Local Breed) and Large White Pigs
P2860
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P2860
Surge in expression of carboxylesterase 1 during the post-neonatal stage enables a rapid gain of the capacity to activate the anti-influenza prodrug oseltamivir.
description
2011 nî lūn-bûn
@nan
2011 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
Surge in expression of carboxy ...... influenza prodrug oseltamivir.
@ast
Surge in expression of carboxy ...... influenza prodrug oseltamivir.
@en
Surge in expression of carboxy ...... influenza prodrug oseltamivir.
@nl
type
label
Surge in expression of carboxy ...... influenza prodrug oseltamivir.
@ast
Surge in expression of carboxy ...... influenza prodrug oseltamivir.
@en
Surge in expression of carboxy ...... influenza prodrug oseltamivir.
@nl
prefLabel
Surge in expression of carboxy ...... influenza prodrug oseltamivir.
@ast
Surge in expression of carboxy ...... influenza prodrug oseltamivir.
@en
Surge in expression of carboxy ...... influenza prodrug oseltamivir.
@nl
P2093
P2860
P356
P1476
Surge in expression of carboxy ...... influenza prodrug oseltamivir.
@en
P2093
Bingfang Yan
Brian E Davies
Dongfang Yang
Eric P Prinssen
P2860
P304
P356
10.1093/INFDIS/JIQ145
P407
P577
2011-04-01T00:00:00Z