In the search for specific inhibitors of human 11beta-hydroxysteroid-dehydrogenases (11beta-HSDs): chenodeoxycholic acid selectively inhibits 11beta-HSD-I
about
The role of glucocorticoid action in the pathophysiology of the Metabolic SyndromeVirtual screening as a strategy for the identification of xenobiotics disrupting corticosteroid action11beta-hydroxysteroid dehydrogenase type 1 inhibitors for the treatment of type 2 diabetes.Bupropion metabolism by human placenta.Bile acids modulate glucocorticoid metabolism and the hypothalamic-pituitary-adrenal axis in obstructive jaundice.Ketoconazole enantiomer for the treatment of diabetes mellitus.11β-Hydroxysteroid dehydrogenase type 1: relevance of its modulation in the pathophysiology of obesity, the metabolic syndrome and type 2 diabetes mellitus.Generation and application of drug indication inference models using typed network motif comparison analysis.Evidence for expression of 11β-hydroxysteroid dehydrogenase type3 (HSD11B3/HSD11B1L) in neonatal pig testis.Metabolism of bupropion by baboon hepatic and placental microsomes.Human carbonyl reduction pathways and a strategy for their study in vitro.Mechanisms of disease: Selective inhibition of 11beta-hydroxysteroid dehydrogenase type 1 as a novel treatment for the metabolic syndrome.11β-hydroxysteroid dehydrogenases: intracellular gate-keepers of tissue glucocorticoid action.11Beta-hydroxysteroid dehydrogenase type 2 and the regulation of surfactant protein A by dexamethasone metabolites.Functional expression, characterization, and purification of the catalytic domain of human 11-beta -hydroxysteroid dehydrogenase type 1.Effects of glycyrrhetinic acid derivatives on hepatic and renal 11beta-hydroxysteroid dehydrogenase activities in rats.The environmental obesogen bisphenol A promotes adipogenesis by increasing the amount of 11β-hydroxysteroid dehydrogenase type 1 in the adipose tissue of children.Inhibition of microsomal cortisol production by (-)-epigallocatechin-3-gallate through a redox shift in the endoplasmic reticulum--a potential new target for treating obesity-related diseases.Influence of human serum albumin on the bile acid-mediated inhibition of liver microsomal type 1 11β-hydroxysteroid dehydrogenase.The selectivity of tyrosine 280 of human 11beta-hydroxysteroid dehydrogenase type 1 in inhibitor binding.Isolation of a novel glycyrrhizin metabolite as a causal candidate compound for pseudoaldosteronism11-Beta-hydroxysteroid dehydrogenase type 1 (11β-HSD1) inhibitors in Type 2 diabetes mellitus and obesity
P2860
Q24803696-3AAFDDB9-BB84-4081-A0A4-019052BE8AA5Q28484229-612F71AF-4F86-43EC-8CE3-BBF6DA824DC8Q30392597-F0A5CF5E-5D01-4A64-99BC-82F8EF277974Q33759322-9DB907EF-6FF1-4EBA-AFE2-7F3F5EE357FBQ33882285-91056927-7F4D-4E49-A546-CC651A1A553AQ34090860-CEE027F5-6D0A-4DCF-B8AA-185B4B1418E6Q34253331-A79679DC-17C0-4FF2-BF43-D02CCB32479CQ34659168-49EB7A8C-AE2B-45B9-B86C-C34F5EE11030Q34861580-2F494C3E-15C0-4FF4-B9A7-D767528E978AQ35072047-470AB0AB-0371-4093-9E7F-22BD5D959170Q35828036-AA4DDA72-DAEB-4676-A839-1E3224D56016Q36575445-68167AB4-D14D-4FE3-BEAA-27B96959E454Q37655884-78EA50CE-72C9-4D42-8ED7-8C36CDD55BA7Q40355645-7F51113E-24A6-4E0A-BAF2-400178845001Q40714438-75DE9A44-8D0F-47A8-960E-E6B306F77FD6Q42166595-88528A79-90AD-43AB-9068-5D12AFF5A286Q42715171-43F6F368-5FB4-4143-A6CE-23393AB919C9Q45396025-9F2577D0-5BFF-4324-9FAC-90855DFD4C35Q46854402-97DD883E-441E-46C1-A994-91026339D107Q51799660-6012247F-3FE0-4EF8-B4F7-DF7E87F07020Q57805805-16EF057B-97B9-4A62-B78E-28B5B1B2CC6CQ58896395-E2CAA38C-0774-43BF-9C6C-387850D41701
P2860
In the search for specific inhibitors of human 11beta-hydroxysteroid-dehydrogenases (11beta-HSDs): chenodeoxycholic acid selectively inhibits 11beta-HSD-I
description
2000 nî lūn-bûn
@nan
2000 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2000 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2000年の論文
@ja
2000年論文
@yue
2000年論文
@zh-hant
2000年論文
@zh-hk
2000年論文
@zh-mo
2000年論文
@zh-tw
2000年论文
@wuu
name
In the search for specific inh ...... ectively inhibits 11beta-HSD-I
@ast
In the search for specific inh ...... ectively inhibits 11beta-HSD-I
@en
In the search for specific inh ...... ectively inhibits 11beta-HSD-I
@nl
type
label
In the search for specific inh ...... ectively inhibits 11beta-HSD-I
@ast
In the search for specific inh ...... ectively inhibits 11beta-HSD-I
@en
In the search for specific inh ...... ectively inhibits 11beta-HSD-I
@nl
prefLabel
In the search for specific inh ...... ectively inhibits 11beta-HSD-I
@ast
In the search for specific inh ...... ectively inhibits 11beta-HSD-I
@en
In the search for specific inh ...... ectively inhibits 11beta-HSD-I
@nl
P2093
P356
P1476
In the search for specific inh ...... ectively inhibits 11beta-HSD-I
@en
P2093
C Grossmann
M Herrmann
M Quinkler
S Diederich
P356
10.1530/EJE.0.1420200
P407
P577
2000-02-01T00:00:00Z