Mechanisms of disease: Selective inhibition of 11beta-hydroxysteroid dehydrogenase type 1 as a novel treatment for the metabolic syndrome.
about
Mutations of key hydrophobic surface residues of 11β-hydroxysteroid dehydrogenase type 1 increase solubility and monodispersity in a bacterial expression systemOptimization of 1,2,4-Triazolopyridines as Inhibitors of Human 11β-Hydroxysteroid Dehydrogenase Type 1 (11β-HSD-1)11beta-Hydroxysteroid Dehydrogenase Type 1 Regulation by Intracellular Glucose 6-Phosphate Provides Evidence for a Novel Link between Glucose Metabolism and Hypothalamo-Pituitary-Adrenal Axis FunctionAdaptive variation regulates the expression of the human SGK1 gene in response to stressCortisone-reductase deficiency associated with heterozygous mutations in 11beta-hydroxysteroid dehydrogenase type 1.A switch in hepatic cortisol metabolism across the spectrum of non alcoholic fatty liver disease.Steroid biomarkers and genetic studies reveal inactivating mutations in hexose-6-phosphate dehydrogenase in patients with cortisone reductase deficiencyDiscovery of adamantyl heterocyclic ketones as potent 11β-hydroxysteroid dehydrogenase type 1 inhibitorsThe multifaceted mineralocorticoid receptorFourth-Generation Progestins Inhibit 3β-Hydroxysteroid Dehydrogenase Type 2 and Modulate the Biosynthesis of Endogenous Steroids.Biomarkers of hypothalamic-pituitary-adrenal axis activity in mice lacking 11β-HSD1 and H6PDHInsulin and dexamethasone dynamically regulate adipocyte 11beta-hydroxysteroid dehydrogenase type 1.Sphingolipids, insulin resistance, and metabolic disease: new insights from in vivo manipulation of sphingolipid metabolism.Can licorice lick colon cancer?Metabolic syndrome in patients with hematological diseases.Male 11β-HSD1 Knockout Mice Fed Trans-Fats and Fructose Are Not Protected From Metabolic Syndrome or Nonalcoholic Fatty Liver Disease.Fasting hyperglycemia in the Goto-Kakizaki rat is dependent on corticosterone: a confounding variable in rodent models of type 2 diabetes.Novel fat depot-specific mechanisms underlie resistance to visceral obesity and inflammation in 11 β-hydroxysteroid dehydrogenase type 1-deficient mice.Expression of cortisol metabolism-related genes shows circadian rhythmic patterns in human adipose tissue.Enhanced hexose-6-phosphate dehydrogenase expression in adipose tissue may contribute to diet-induced visceral adiposity.GIP receptor antagonism reverses obesity, insulin resistance, and associated metabolic disturbances induced in mice by prolonged consumption of high-fat diet
P2860
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P2860
Mechanisms of disease: Selective inhibition of 11beta-hydroxysteroid dehydrogenase type 1 as a novel treatment for the metabolic syndrome.
description
2005 nî lūn-bûn
@nan
2005年の論文
@ja
2005年論文
@yue
2005年論文
@zh-hant
2005年論文
@zh-hk
2005年論文
@zh-mo
2005年論文
@zh-tw
2005年论文
@wuu
2005年论文
@zh
2005年论文
@zh-cn
name
Mechanisms of disease: Selecti ...... nt for the metabolic syndrome.
@ast
Mechanisms of disease: Selecti ...... nt for the metabolic syndrome.
@en
Mechanisms of disease: Selecti ...... nt for the metabolic syndrome.
@en-gb
type
label
Mechanisms of disease: Selecti ...... nt for the metabolic syndrome.
@ast
Mechanisms of disease: Selecti ...... nt for the metabolic syndrome.
@en
Mechanisms of disease: Selecti ...... nt for the metabolic syndrome.
@en-gb
prefLabel
Mechanisms of disease: Selecti ...... nt for the metabolic syndrome.
@ast
Mechanisms of disease: Selecti ...... nt for the metabolic syndrome.
@en
Mechanisms of disease: Selecti ...... nt for the metabolic syndrome.
@en-gb
P2860
P356
P1476
Mechanisms of disease: Selecti ...... nt for the metabolic syndrome.
@en
P2860
P356
10.1038/NCPENDMET0023
P577
2005-12-01T00:00:00Z