Design and synthesis of lipophilic phosphoramidate d4T-MP prodrugs expressing high potency against HIV in cell culture: structural determinants for in vitro activity and QSAR
about
Synthesis of nucleoside phosphate and phosphonate prodrugsSynthesis and antiviral activity of aryl phosphoramidate derivatives of beta-D- and beta-L-C-5-substituted 2',3'-didehydro-2',3'-dideoxy-uridine bearing linker arms.Novel compounds in preclinical/early clinical development for the treatment of HIV infections.New anti-HIV agents and targets.Synthesis and antiviral evaluation of phosphoramidate derivatives of (E)-5-(2-bromovinyl)-2'-deoxyuridine.Cathepsin A is the major hydrolase catalyzing the intracellular hydrolysis of the antiretroviral nucleotide phosphonoamidate prodrugs GS-7340 and GS-9131.Practical synthesis, separation, and stereochemical assignment of the PMPA pro-drug GS-7340.Synthesis of new homo and heterodinucleosides containing the 2',3'-dideoxynucleosides AZT and D4T.Effects of aryl substituents on the anti-HIV activity of the arylphosphoramidate derivatives of stavudine.Quantitative structure-activity relationship study on some azidopyridinyl neonicotinoid insecticides for their selective affinity towards the drosophila nicotinic receptor over mammalian alpha4beta2 receptor using electrotopological state atom indexPhosphoramidate protides of carbocyclic 2',3'-dideoxy-2',3'-didehydro-7-deazaadenosine with potent activity against HIV and HBV.A novel synthesis of antiviral nucleoside phosphoramidate and thiophosphoramidate prodrugs via nucleoside H-phosphonamidates.Strategies in the Design of Antiviral Drugs
P2860
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P2860
Design and synthesis of lipophilic phosphoramidate d4T-MP prodrugs expressing high potency against HIV in cell culture: structural determinants for in vitro activity and QSAR
description
1999 nî lūn-bûn
@nan
1999 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
1999 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
1999年の論文
@ja
1999年論文
@yue
1999年論文
@zh-hant
1999年論文
@zh-hk
1999年論文
@zh-mo
1999年論文
@zh-tw
1999年论文
@wuu
name
Design and synthesis of lipoph ...... for in vitro activity and QSAR
@ast
Design and synthesis of lipoph ...... for in vitro activity and QSAR
@en
Design and synthesis of lipoph ...... for in vitro activity and QSAR
@nl
type
label
Design and synthesis of lipoph ...... for in vitro activity and QSAR
@ast
Design and synthesis of lipoph ...... for in vitro activity and QSAR
@en
Design and synthesis of lipoph ...... for in vitro activity and QSAR
@nl
prefLabel
Design and synthesis of lipoph ...... for in vitro activity and QSAR
@ast
Design and synthesis of lipoph ...... for in vitro activity and QSAR
@en
Design and synthesis of lipoph ...... for in vitro activity and QSAR
@nl
P50
P356
P1476
Design and synthesis of lipoph ...... for in vitro activity and QSAR
@en
P2093
A Q Siddiqui
I H Gilbert
P304
P356
10.1021/JM9807104
P407
P577
1999-10-07T00:00:00Z