High-affinity agonist binding correlates with efficacy (intrinsic activity) at the human serotonin 5-HT2A and 5-HT2C receptors: evidence favoring the ternary complex and two-state models of agonist action

High-affinity agonist binding correlates with efficacy (intrinsic activity) at the human serotonin 5-HT2A and 5-HT2C receptors: evidence favoring the ternary complex and two-state models of agonist action

Item
http://www.wikidata.org/entity/Q28374171
The serotonin 2C receptor potently modulates the head-twitch response in mice induced by a phenethylamine hallucinogenLSD but not lisuride disrupts prepulse inhibition in rats by activating the 5-HT(2A) receptor.The Concise Guide to PHARMACOLOGY 2013/14: G protein-coupled receptorsRadiosynthesis and in vivo evaluation of a series of substituted 11C-phenethylamines as 5-HT (2A) agonist PET tracers.Presynaptic selectivity of a ligand for serotonin 1A receptors revealed by in vivo PET assays of rat brain.Differences in potency and efficacy of a series of phenylisopropylamine/phenylethylamine pairs at 5-HT(2A) and 5-HT(2C) receptors.Fine-tuning serotonin2c receptor function in the brain: molecular and functional implicationsExtended characterisation of the serotonin 2A (5-HT2A) receptor-selective PET radiotracer 11C-MDL100907 in humans: quantitative analysis, test-retest reproducibility, and vulnerability to endogenous 5-HT tone.Functional topography of serotonergic systems supports the Deakin/Graeff hypothesis of anxiety and affective disorders.Optimising PET approaches to measuring 5-HT release in human brain.Considerations in the Development of Reversibly Binding PET Radioligands for Brain Imaging.Fenfluramine Reduces [11C]Cimbi-36 Binding to the 5-HT2A Receptor in the Nonhuman Primate BrainAnalysis of molecular determinants of affinity and relative efficacy of a series of R- and S-2-(dipropylamino)tetralins at the 5-HT1A serotonin receptor.5-HT(1A) receptor agonist-antagonist binding affinity difference as a measure of intrinsic activity in recombinant and native tissue systems.Mechanisms of ligand binding and efficacy at the human D2(short) dopamine receptor.Similar serotonin-2A receptor binding in rats with different coping styles or levels of aggression.Ex vivo evaluation of the serotonin 1A receptor partial agonist [3H]CUMI-101 in awake rats
P2860

High-affinity agonist binding correlates with efficacy (intrinsic activity) at the human serotonin 5-HT2A and 5-HT2C receptors: evidence favoring the ternary complex and two-state models of agonist action

Item
http://www.wikidata.org/entity/Q28374171
description
1999 nî lūn-bûn
@nan
1999 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
1999 թվականի մայիսին հրատարակված գիտական հոդված
@hy
1999年の論文
@ja
1999年論文
@yue
1999年論文
@zh-hant
1999年論文
@zh-hk
1999年論文
@zh-mo
1999年論文
@zh-tw
1999年论文
@wuu
name
High-affinity agonist binding ...... state models of agonist action
@ast
High-affinity agonist binding ...... state models of agonist action
@en
High-affinity agonist binding ...... state models of agonist action
@nl
type
label
High-affinity agonist binding ...... state models of agonist action
@ast
High-affinity agonist binding ...... state models of agonist action
@en
High-affinity agonist binding ...... state models of agonist action
@nl
prefLabel
High-affinity agonist binding ...... state models of agonist action
@ast
High-affinity agonist binding ...... state models of agonist action
@en
High-affinity agonist binding ...... state models of agonist action
@nl
P1433
P1476
P2093
P2860
P304
P31
P356
P407
P433
P478
P577
P5875
P698
P921
P356
P1433
P1476
High-affinity agonist binding ...... state models of agonist action
@en
P2093
P2860
P304
P31
P356
10.1046/J.1471-4159.1999.0722127.X
P407
P433
P478
P577
P5875
P698
P921