Radiosyntheses and in vivo evaluation of carbon-11 PET tracers for PDE10A in the brain of rodent and nonhuman primate - Wikidata - awgldk - TriplyDB

Radiosyntheses and in vivo evaluation of carbon-11 PET tracers for PDE10A in the brain of rodent and nonhuman primate

Radiosyntheses and in vivo evaluation of carbon-11 PET tracers for PDE10A in the brain of rodent and nonhuman primate

http://www.wikidata.org/entity/Q28387761

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Novel Radioligands for Cyclic Nucleotide Phosphodiesterase Imaging with Positron Emission Tomography: An Update on Developments Since 2012 Comparison of [(11)C]TZ1964B and [(18)F]MNI659 for PET imaging brain PDE10A in nonhuman primates Development of a series of novel carbon-11 labeled PDE10A inhibitors.Preclinical evaluation of a promising C-11 labeled PET tracer for imaging phosphodiesterase 10A in the brain of living subject Synthesis of Fluorine-Containing Phosphodiesterase 10A (PDE10A) Inhibitors and the In Vivo Evaluation of F-18 Labeled PDE10A PET Tracers in Rodent and Nonhuman Primate.Kinetics modeling and occupancy studies of a novel C-11 PET tracer for VAChT in nonhuman primates.A novel thermoregulatory role for PDE10A in mouse and human adipocytes Radiosynthesis and in vivo evaluation of a novel σ1 selective PET ligand.Molecular Imaging of PDE10A Knockout Mice with a Novel PET Radiotracer: [(11)C]T-773.In vivo characterization of two 18F-labeled PDE10A PET radioligands in nonhuman primate brains.Synthesis, resolution, and in vitro evaluation of three vesicular acetylcholine transporter ligands and evaluation of the lead fluorine-18 radioligand in a nonhuman primate.

P2860

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P2860

Radiosyntheses and in vivo evaluation of carbon-11 PET tracers for PDE10A in the brain of rodent and nonhuman primate

http://www.wikidata.org/entity/Q28387761

description

2014 nî lūn-bûn

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2014 թուականի Մայիսին հրատարակուած գիտական յօդուած

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2014 թվականի մայիսին հրատարակված գիտական հոդված

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2014年の論文

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Radiosyntheses and in vivo eva ...... of rodent and nonhuman primate

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Radiosyntheses and in vivo eva ...... of rodent and nonhuman primate

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Radiosyntheses and in vivo eva ...... of rodent and nonhuman primate

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Radiosyntheses and in vivo eva ...... of rodent and nonhuman primate

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Radiosyntheses and in vivo eva ...... of rodent and nonhuman primate

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Radiosyntheses and in vivo eva ...... of rodent and nonhuman primate

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J.BMC.2014.03.028

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Bioorganic & Medicinal Chemistry

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Radiosyntheses and in vivo eva ...... of rodent and nonhuman primate

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Hongjun Jin

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Hubert P Flores

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Jinda Fan

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Joel S Perlmutter

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Junfeng Li

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Prashanth K Padakanti

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Xiang Zhang

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Yi Su

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P2860

Cloning and characterization of a novel human phosphodiesterase that hydrolyzes both cAMP and cGMP (PDE10A)

Distinct roles of PDE4 and PDE10A in the regulation of cAMP/PKA signaling in the striatum

Discovery of a novel class of phosphodiesterase 10A inhibitors and identification of clinical candidate 2-[4-(1-methyl-4-pyridin-4-yl-1H-pyrazol-3-yl)-phenoxymethyl]-quinoline (PF-2545920) for the treatment of schizophrenia

Phosphodiesterases in the CNS: targets for drug development

Cyclic nucleotide phosphodiesterases: molecular regulation to clinical use

Radiosynthesis and in vivo evaluation of [11C]MP-10 as a PET probe for imaging PDE10A in rodent and non-human primate brain

Cellular and subcellular localization of PDE10A, a striatum-enriched phosphodiesterase

Isolation and characterization of a dual-substrate phosphodiesterase gene family: PDE10A

Isolation and characterization of PDE10A, a novel human 3', 5'-cyclic nucleotide phosphodiesterase.

Radiopharmaceutical chemistry for positron emission tomography.

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