about
Synthesis and in vitro and in vivo evaluation of 18F-labeled positron emission tomography (PET) ligands for imaging the vesicular acetylcholine transporterRadiosynthesis and in vivo evaluation of [11C]MP-10 as a PET probe for imaging PDE10A in rodent and non-human primate brainRadiosyntheses and in vivo evaluation of carbon-11 PET tracers for PDE10A in the brain of rodent and nonhuman primateComparison of [(11)C]TZ1964B and [(18)F]MNI659 for PET imaging brain PDE10A in nonhuman primates4-aroylpiperidines and 4-(α-hydroxyphenyl)piperidines as selective sigma-1 receptor ligands: synthesis, preliminary pharmacological evaluation and computational studiesPreclinical evaluation of the novel monoclonal antibody H6-11 for prostate cancer imaging.Neuroprotective effects of high affinity Σ1 receptor selective compounds.PET Study of Sphingosine-1-Phosphate Receptor 1 Expression in Response to Vascular Inflammation in a Rat Model of Carotid Injury.Identification of the PGRMC1 protein complex as the putative sigma-2 receptor binding site.Binding of the radioligand SIL23 to α-synuclein fibrils in Parkinson disease brain tissue establishes feasibility and screening approaches for developing a Parkinson disease imaging agent.Synthesis and evaluation of 15-(4-(2-[¹⁸F]Fluoroethoxy)phenyl)pentadecanoic acid: a potential PET tracer for studying myocardial fatty acid metabolism.Chemical and enzyme-assisted syntheses of norbuprenorphine-3-β-D-glucuronide.The novel sigma-2 receptor ligand SW43 stabilizes pancreas cancer progression in combination with gemcitabine.Synthesis and in vitro characterization of cinnoline and benzimidazole analogues as phosphodiesterase 10A inhibitors.Synthesis and in vitro biological evaluation of carbonyl group-containing analogues for σ1 receptors.Synthesis and in vitro evaluation of new analogues as inhibitors for phosphodiesterase 10A.In vitro and ex vivo characterization of (-)-TZ659 as a ligand for imaging the vesicular acetylcholine transporterAutomated radiochemical synthesis and biodistribution of [¹¹C]l-α-acetylmethadol ([¹¹C]LAAM).A practical process for the preparation of [(32)P]S1P and binding assay for S1P receptor ligandsA potent and selective C-11 labeled PET tracer for imaging sphingosine-1-phosphate receptor 2 in the CNS demonstrates sexually dimorphic expression.Sigma-2 ligands induce tumour cell death by multiple signalling pathways.Synthesis and biological characterization of a promising F-18 PET tracer for vesicular acetylcholine transporter.Synthesis and evaluation of in vitro bioactivity for vesicular acetylcholine transporter inhibitors containing two carbonyl groups.Synthesis and in vitro evaluation of α-synuclein ligands.Preclinical evaluation of a promising C-11 labeled PET tracer for imaging phosphodiesterase 10A in the brain of living subjectDesign, Synthesis, and Characterization of 3-(Benzylidene)indolin-2-one Derivatives as Ligands for α-Synuclein Fibrils.Glycan array analysis of the antigen repertoire targeted by tumor-binding antibodiesKinetics modeling and occupancy studies of a novel C-11 PET tracer for VAChT in nonhuman primates.Design, Synthesis, and In Vitro and In Vivo Evaluation of an (18)F-Labeled Sphingosine 1-Phosphate Receptor 1 (S1P1) PET Tracer.C-11 radiochemistry in cancer imaging applications.Synthesis and structure-activity relationship studies of conformationally flexible tetrahydroisoquinolinyl triazole carboxamide and triazole substituted benzamide analogues as σ2 receptor ligands.Functional assays to define agonists and antagonists of the sigma-2 receptor.Synthesis and in vitro biological evaluation of pyrazole group-containing analogues for PDE10A.In vitro and in vivo characterization of two C-11-labeled pet tracers for vesicular acetylcholine transporter.Syntheses and radiosyntheses of two carbon-11 labeled potent and selective radioligands for imaging vesicular acetylcholine transporter.Synthesis and characterization of selective dopamine D2 receptor antagonists.Carbon-11 labeled papaverine as a PET tracer for imaging PDE10A: radiosynthesis, in vitro and in vivo evaluation.Synthesis and in vitro binding of N-phenyl piperazine analogs as potential dopamine D3 receptor ligands.PET Imaging Study of S1PR1 Expression in a Rat Model of Multiple SclerosisSynthesis, radiolabeling and initial in vivo evaluation of [(11)C]KSM-01 for imaging PPAR-α receptors.
P50
Q24650088-BE8E7ED0-347A-4E04-B46B-B7DC6D7290E5Q28386823-416926BD-3BE2-4D50-8ABC-7DB70124F44DQ28387761-4CA31E0C-78BE-4F49-945E-5D1B95462311Q28390557-06A6BF7B-A0BC-4752-9D4A-9C06B21603F1Q28829344-B335C62F-9F66-4DA4-A28D-7E0093AF5275Q33652622-249653C8-D4A8-403C-A22F-0BE308E47EACQ33745942-4FFC5AB7-098D-4EF3-B596-6933563ADF7DQ33795454-DA097436-0CF0-4535-8981-0E592E422986Q34197697-F4724963-EDA8-44FB-8052-B70E7738BA7DQ34584062-599C7C37-6BB0-47EF-BDFD-ADBB35D41ACAQ34700405-6C395BB0-F52D-4AA5-9EE8-CD7BF64DAB66Q34965527-41138F5F-EC99-422A-96C5-F773F1C9A905Q35021013-55CB565C-65DE-4F22-A4ED-A0C5A8B3240AQ35063956-26FDFC9D-6461-45C0-A186-1D352C881886Q35148443-D716838E-FE8E-407A-98F9-D92EA85203FAQ35190040-DAE6125E-421F-429B-9C1F-AD1FD14C180DQ35204649-E891B6C8-A63F-4907-B6D5-BD14C45B36E2Q35258947-60B792A8-14BC-427A-A47D-3B7E10DD378DQ35688716-7D092D8F-13F9-485E-BA21-4325A35EB6C1Q35868052-7CB4BF2B-4BEB-48D8-BE67-0B40E26CCCE9Q35879869-6A5C2201-A468-4B79-BCE6-4F627FAA89EBQ35915048-DB16073A-89C5-4222-BB8C-EF15DBBC9418Q36074777-00354E4A-03D5-4F23-A708-A6982F07E9C0Q36106447-546DDE6D-2E93-4391-BB26-5A4E874254A7Q36157209-ECE43E90-6673-44BF-87D4-BB862FE6B4CDQ36218847-E910909A-A4F1-4DD1-BF1A-C4AB0A43289CQ36340501-2B00234C-809B-4DAE-A7D9-7A3024591494Q36578493-D1083086-1C02-42DB-9D15-AD49109EDB29Q37388254-682861E2-402E-4C6F-954B-E76973095F22Q37730188-F93943BA-2EAD-4014-B959-693C2FA0E0FFQ38995653-E7F9B6DE-6CF9-4D29-8581-810C8D90EFE6Q39044023-43C7A917-9C3A-4275-BA91-99FF9A912280Q39813126-29BEA260-2FCC-4E2A-AB65-E022FB289249Q39830429-76FF1CD7-C766-4F44-801D-7296023135CBQ40078103-45CC16E8-BBC4-4395-A626-69D31A333C41Q40351194-F7B615E1-6542-4167-9AF6-51423D363986Q40424916-55ED7764-1E9D-4495-BDF8-4CBE895AE28EQ40484148-91E9A58D-9BD2-47BD-BEA6-BF8CF3264D15Q41653767-7CC4BB5A-0596-474A-83D6-37C39C483484Q42410907-141F072D-3E0A-4B69-BD00-5AF6410C2EBD
P50
description
onderzoeker
@nl
researcher
@en
հետազոտող
@hy
name
Zhude Tu
@ast
Zhude Tu
@en
Zhude Tu
@es
Zhude Tu
@nl
Zhude Tu
@sl
type
label
Zhude Tu
@ast
Zhude Tu
@en
Zhude Tu
@es
Zhude Tu
@nl
Zhude Tu
@sl
prefLabel
Zhude Tu
@ast
Zhude Tu
@en
Zhude Tu
@es
Zhude Tu
@nl
Zhude Tu
@sl
P106
P1153
8517407300
P31
P496
0000-0003-0325-835X