about
Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)Regulated intramembrane proteolysis of Bri2 (Itm2b) by ADAM10 and SPPL2a/SPPL2bThe disintegrin-like metalloproteinase ADAM10 is involved in constitutive cleavage of CX3CL1 (fractalkine) and regulates CX3CL1-mediated cell-cell adhesionLIMP-2 is a receptor for lysosomal mannose-6-phosphate-independent targeting of beta-glucocerebrosidaseThe proteome of lysosomesMolecular characterisation of 'transmembrane protein 192' (TMEM192), a novel protein of the lysosomal membraneCellular cholesterol depletion triggers shedding of the human interleukin-6 receptor by ADAM10 and ADAM17 (TACE)The disintegrin/metalloprotease ADAM 10 is essential for Notch signalling but not for alpha-secretase activity in fibroblastsThe lysosomal polypeptide transporter TAPL is stabilized by interaction with LAMP-1 and LAMP-2Signal-peptide-peptidase-like 2a (SPPL2a) is targeted to lysosomes/late endosomes by a tyrosine motif in its C-terminal tailStructure of LIMP-2 provides functional insights with implications for SR-BI and CD36The tetraspanin CD63 regulates ESCRT-independent and -dependent endosomal sorting during melanogenesisFurin-, ADAM 10-, and gamma-secretase-mediated cleavage of a receptor tyrosine phosphatase and regulation of beta-catenin's transcriptional activityLysosomal membrane proteins and their central role in physiologyA role for the lysosomal membrane protein LGP85 in the biogenesis and maintenance of endosomal and lysosomal morphologyLIMP-2/LGP85 deficiency causes ureteric pelvic junction obstruction, deafness and peripheral neuropathy in miceAt the acidic edge: emerging functions for lysosomal membrane proteinsRegulated ADAM10-dependent ectodomain shedding of gamma-protocadherin C3 modulates cell-cell adhesionThe transmembrane CXC-chemokine ligand 16 is induced by IFN-gamma and TNF-alpha and shed by the activity of the disintegrin-like metalloproteinase ADAM10Cathepsin B-mediated autophagy flux facilitates the anthrax toxin receptor 2-mediated delivery of anthrax lethal factor into the cytoplasmControl of peripheral nerve myelination by the beta-secretase BACE1Array-based gene discovery with three unrelated subjects shows SCARB2/LIMP-2 deficiency causes myoclonus epilepsy and glomerulosclerosisCellular mechanotransduction relies on tension-induced and chaperone-assisted autophagyLysosomal integral membrane protein 2 is a novel component of the cardiac intercalated disc and vital for load-induced cardiac myocyte hypertrophy
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description
hulumtues
@sq
onderzoeker
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researcher
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ricercatore
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հետազոտող
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name
Paul Saftig
@ast
Paul Saftig
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Paul Saftig
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Paul Saftig
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Paul Saftig
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type
label
Paul Saftig
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Paul Saftig
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Paul Saftig
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Paul Saftig
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Paul Saftig
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prefLabel
Paul Saftig
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Paul Saftig
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Paul Saftig
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Paul Saftig
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Paul Saftig
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P244
P269
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P1207
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P21
P213
0000 0001 1729 7582
P214
P244
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P269
P31
P735
P7859
lccn-n2005182069