Histone deacetylases play a major role in the transcriptional regulation of the Plasmodium falciparum life cycle - Wikidata - awgldk - TriplyDB

Histone deacetylases play a major role in the transcriptional regulation of the Plasmodium falciparum life cycle

Histone deacetylases play a major role in the transcriptional regulation of the Plasmodium falciparum life cycle

http://www.wikidata.org/entity/Q28472603

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Toxoplasma histone acetylation remodelers as novel drug targets Expression of P. falciparum var genes involves exchange of the histone variant H2A.Z at the promoter The MYST family histone acetyltransferase regulates gene expression and cell cycle in malaria parasite Plasmodium falciparum H2A.Z demarcates intergenic regions of the plasmodium falciparum epigenome that are dynamically marked by H3K9ac and H3K4me3 A moonlighting function of Plasmodium falciparum histone 3, mono-methylated at lysine 9?Experimentally controlled downregulation of the histone chaperone FACT in Plasmodium berghei reveals that it is critical to male gamete fertility Ex vivo activity of histone deacetylase inhibitors against multidrug-resistant clinical isolates of Plasmodium falciparum and P. vivax Lysine acetylation in sexual stage malaria parasites is a target for antimalarial small molecules.Malaria gametocytogenesis.Expanding the Antimalarial Drug Arsenal-Now, But How?Artemisinin resistance in Plasmodium falciparum is associated with an altered temporal pattern of transcription.Chromatin-mediated epigenetic regulation in the malaria parasite Plasmodium falciparum.Recent Progress in Functional Genomic Research in Plasmodium falciparum Dynamic activation and repression of the plasmodium falciparum rif gene family and their relation to chromatin modification.Comparative gene expression profiling of P. falciparum malaria parasites exposed to three different histone deacetylase inhibitors Genome-wide analysis in Plasmodium falciparum reveals early and late phases of RNA polymerase II occupancy during the infectious cycle.The Apicomplexan AP2 family: integral factors regulating Plasmodium development.A view on the role of epigenetics in the biology of malaria parasites.Dynamic epigenetic regulation of gene expression during the life cycle of malaria parasite Plasmodium falciparum.Analysis of the molecular mechanisms governing the stage-specific expression of a prototypical housekeeping gene during intraerythrocytic development of P. falciparum.Chemical genomics for studying parasite gene function and interaction.Predicting functional and regulatory divergence of a drug resistance transporter gene in the human malaria parasite Genome cartography: charting the apicomplexan genome.Discovery of HDAC inhibitors with potent activity against multiple malaria parasite life cycle stages Jumbled genomes: missing Apicomplexan synteny Multiple dimensions of epigenetic gene regulation in the malaria parasite Plasmodium falciparum: gene regulation via histone modifications, nucleosome positioning and nuclear architecture in P. falciparum A global transcriptional analysis of Plasmodium falciparum malaria reveals a novel family of telomere-associated lncRNAs.Strand-specific RNA sequencing in Plasmodium falciparum malaria identifies developmentally regulated long non-coding RNA and circular RNA.A serine-arginine-rich (SR) splicing factor modulates alternative splicing of over a thousand genes in Toxoplasma gondii.An integrative analysis of small molecule transcriptional responses in the human malaria parasite Plasmodium falciparum Chromatin modifications, epigenetics, and how protozoan parasites regulate their lives.Antimalarial activity of the anticancer histone deacetylase inhibitor SB939.An assay to probe Plasmodium falciparum growth, transmission stage formation and early gametocyte development New Agilent platform DNA microarrays for transcriptome analysis of Plasmodium falciparum and Plasmodium berghei for the malaria research community Design and Synthesis of Novel Anti-Plasmodial Histone Deacetylase Inhibitors Containing an Alkoxyamide Connecting Unit.Proteome-wide analysis reveals widespread lysine acetylation of major protein complexes in the malaria parasite.DNA damage regulation and its role in drug-related phenotypes in the malaria parasites Discovery of a Selective Series of Inhibitors of Plasmodium falciparum HDACs Comparative effects of histone deacetylases inhibitors and resveratrol on Trypanosoma cruzi replication, differentiation, infectivity and gene expression.Effect of clinically approved HDAC inhibitors on Plasmodium, Leishmania and Schistosoma parasite growth.

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P2860

Histone deacetylases play a major role in the transcriptional regulation of the Plasmodium falciparum life cycle

http://www.wikidata.org/entity/Q28472603

description

2010 nî lūn-bûn

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2010 թուականի Յունուարին հրատարակուած գիտական յօդուած

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2010 թվականի հունվարին հրատարակված գիտական հոդված

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2010年の論文

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2010年論文

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2010年論文

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2010年論文

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2010年論文

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2010年論文

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JOURNAL.PPAT.1000737

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Histone deacetylases play a ma ...... asmodium falciparum life cycle

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Archna P Gupta

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Balbir K Chaal

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Brigitta D Wastuwidyaningtyas

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Yen-Hoon Luah

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P2860

The transcriptome of the intraerythrocytic developmental cycle of Plasmodium falciparum

Genome sequence of the human malaria parasite Plasmodium falciparum

Discovery of the principal specific transcription factors of Apicomplexa and their implication for the evolution of the AP2-integrase DNA binding domains

MYST family histone acetyltransferases in the protozoan parasite Toxoplasma gondii.

Significance analysis of microarrays applied to the ionizing radiation response

FoxA1 translates epigenetic signatures into enhancer-driven lineage-specific transcription

Expression profiling of the schizont and trophozoite stages of Plasmodium falciparum with a long-oligonucleotide microarray

Plasmodium falciparum heterochromatin protein 1 marks genomic loci linked to phenotypic variation of exported virulence factors

High-resolution profiling of histone methylations in the human genome

Chromatin modifications and their function

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e1000737

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3705625

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10.1371/JOURNAL.PPAT.1000737

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1

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6

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41166521

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20107518

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Plasmodium falciparum

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2809759

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