The antipsychotic thioridazine shows promising therapeutic activity in a mouse model of multidrug-resistant tuberculosis
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Thioridazine has potent antitumor effects on lung cancer stem-like cells.Reduced emergence of isoniazid resistance with concurrent use of thioridazine against acute murine tuberculosis.Rifamycin action on RNA polymerase in antibiotic-tolerant Mycobacterium tuberculosis results in differentially detectable populations.Synergistic drug combinations for tuberculosis therapy identified by a novel high-throughput screen.Sterilizing activity of thioridazine in combination with the first-line regimen against acute murine tuberculosis.Finding alternatives to antibiotics.Combination approaches to combat multidrug-resistant bacteria.Antitubercular specific activity of ibuprofen and the other 2-arylpropanoic acids using the HT-SPOTi whole-cell phenotypic assay.Pyrazinamide may improve fluoroquinolone-based treatment of multidrug-resistant tuberculosis.Antitubercular pharmacodynamics of phenothiazinesThioridazine lacks bactericidal activity in an animal model of extracellular tuberculosis.Antipsychotic agent thioridazine sensitizes renal carcinoma Caki cells to TRAIL-induced apoptosis through reactive oxygen species-mediated inhibition of Akt signaling and downregulation of Mcl-1 and c-FLIP(L)Thioridazine enhances sensitivity to carboplatin in human head and neck cancer cells through downregulation of c-FLIP and Mcl-1 expression.Phenothiazines as anti-tubercular agents: mechanistic insights and clinical implications.Antituberculosis drug research: a critical overview.Is repositioning of drugs a viable alternative in the treatment of tuberculosis?Why and How the Old Neuroleptic Thioridazine Cures the XDR-TB Patient.Role of Phenothiazines and Structurally Similar Compounds of Plant Origin in the Fight against Infections by Drug Resistant Bacteria.Thioridazine: A Non-Antibiotic Drug Highly Effective, in Combination with First Line Anti-Tuberculosis Drugs, against Any Form of Antibiotic Resistance of Mycobacterium tuberculosis Due to Its Multi-Mechanisms of Action.Type-II NADH Dehydrogenase (NDH-2): a promising therapeutic target for antitubercular and antibacterial drug discovery.Inhibition of Bacterial RNase P RNA by Phenothiazine Derivatives.Addressing the tuberculosis-depression syndemic to end the tuberculosis epidemic.Thioridazine in PLGA nanoparticles reduces toxicity and improves rifampicin therapy against mycobacterial infection in zebrafish.Bioenergetics of Mycobacterium: An Emerging Landscape for Drug Discovery.Efflux Activity Differentially Modulates the Levels of Isoniazid and Rifampicin Resistance among Multidrug Resistant and Monoresistant Mycobacterium tuberculosis Strains.Gene module analysis of juvenile myelomonocytic leukemia and screening of anticancer drugsChallenging the Drug-Likeness Dogma for New Drug Discovery in TuberculosisEfflux Pumps in Mycobacteria: Antimicrobial Resistance, Physiological Functions, and Role in Pathogenicity
P2860
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P2860
The antipsychotic thioridazine shows promising therapeutic activity in a mouse model of multidrug-resistant tuberculosis
description
2010 nî lūn-bûn
@nan
2010 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
The antipsychotic thioridazine ...... ltidrug-resistant tuberculosis
@ast
The antipsychotic thioridazine ...... ltidrug-resistant tuberculosis
@en
The antipsychotic thioridazine ...... ltidrug-resistant tuberculosis
@nl
type
label
The antipsychotic thioridazine ...... ltidrug-resistant tuberculosis
@ast
The antipsychotic thioridazine ...... ltidrug-resistant tuberculosis
@en
The antipsychotic thioridazine ...... ltidrug-resistant tuberculosis
@nl
prefLabel
The antipsychotic thioridazine ...... ltidrug-resistant tuberculosis
@ast
The antipsychotic thioridazine ...... ltidrug-resistant tuberculosis
@en
The antipsychotic thioridazine ...... ltidrug-resistant tuberculosis
@nl
P2093
P2860
P50
P3181
P1433
P1476
The antipsychotic thioridazine ...... ltidrug-resistant tuberculosis
@en
P2093
Cecile Magis-Escurra
Diana Aguilar
Hector Orozco
Martin J Boeree
Rogelio Hernandez-Pando
P2860
P304
P3181
P356
10.1371/JOURNAL.PONE.0012640
P407
P577
2010-09-09T00:00:00Z