Human disease-drug network based on genomic expression profiles
about
Systems Pharmacology in Small Molecular Drug DiscoverySystematic analysis of the associations between adverse drug reactions and pathwaysA Glimpse to Background and Characteristics of Major Molecular Biological NetworksStructure and dynamics of molecular networks: a novel paradigm of drug discovery: a comprehensive reviewThe emerging paradigm of network medicine in the study of human diseasePREDICT: a method for inferring novel drug indications with application to personalized medicineUsing Pharmacogenomic Databases for Discovering Patient-Target Genes and Small Molecule Candidates to Cancer TherapyNetwork-based elucidation of human disease similarities reveals common functional modules enriched for pluripotent drug targetsDrug-induced regulation of target expressionSystematic drug repositioning based on clinical side-effectsUsing functional signatures to identify repositioned drugs for breast, myelogenous leukemia and prostate cancerSystems biological approach of molecular descriptors connectivity: optimal descriptors for oral bioavailability predictionCDA: combinatorial drug discovery using transcriptional response modulesCharacterizing the network of drugs and their affected metabolic subpathwaysDrug target prediction and repositioning using an integrated network-based approachThe landscape of host transcriptional response programs commonly perturbed by bacterial pathogens: towards host-oriented broad-spectrum drug targetsDrug repositioning by kernel-based integration of molecular structure, molecular activity, and phenotype dataSemFunSim: a new method for measuring disease similarity by integrating semantic and gene functional associationA network-based classification model for deriving novel drug-disease associations and assessing their molecular actionsThe human disease network in terms of dysfunctional regulatory mechanismsA Semi-Supervised Approach for Refining Transcriptional Signatures of Drug Response and Repositioning PredictionsDrug Repositioning for Cancer Therapy Based on Large-Scale Drug-Induced Transcriptional SignaturesA Drug-Centric View of Drug Development: How Drugs Spread from Disease to DiseaseNetwork-based in silico drug efficacy screeningA miRNA-driven inference model to construct potential drug-disease associations for drug repositioningVNP: Interactive Visual Network Pharmacology of Diseases, Targets, and DrugsA Systematic Framework for Drug Repositioning from Integrated Omics and Drug Phenotype Profiles Using Pathway-Drug NetworkA genomewide association study of nicotine and alcohol dependence in Australian and Dutch populations.Rational drug repositioning guided by an integrated pharmacological network of protein, disease and drug.Large-scale phenome analysis defines a behavioral signature for Huntington's disease genotype in mice.Transcriptional data: a new gateway to drug repositioning?DvD: An R/Cytoscape pipeline for drug repurposing using public repositories of gene expression data.Finding the targets of a drug by integration of gene expression data with a protein interaction network.Computational drug repositioning: from data to therapeutics.Prediction of novel drug indications using network driven biological data prioritization and integration.Inferring drug-disease associations from integration of chemical, genomic and phenotype data using network propagation.Prediction of gene-based drug indications using compendia of public gene expression data and PubMed abstracts.Systems biology in the context of big data and networks.A computational method for drug repositioning using publicly available gene expression data.Fusing literature and full network data improves disease similarity computation.
P2860
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P2860
Human disease-drug network based on genomic expression profiles
description
2009 nî lūn-bûn
@nan
2009 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2009 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
2009年の論文
@ja
2009年論文
@yue
2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
@wuu
name
Human disease-drug network based on genomic expression profiles
@ast
Human disease-drug network based on genomic expression profiles
@en
Human disease-drug network based on genomic expression profiles
@nl
type
label
Human disease-drug network based on genomic expression profiles
@ast
Human disease-drug network based on genomic expression profiles
@en
Human disease-drug network based on genomic expression profiles
@nl
prefLabel
Human disease-drug network based on genomic expression profiles
@ast
Human disease-drug network based on genomic expression profiles
@en
Human disease-drug network based on genomic expression profiles
@nl
P2860
P3181
P1433
P1476
Human disease-drug network based on genomic expression profiles
@en
P2093
Guanghui Hu
P2860
P3181
P356
10.1371/JOURNAL.PONE.0006536
P407
P577
2009-08-06T00:00:00Z