Acquisition of aneuploidy provides increased fitness during the evolution of antifungal drug resistance - Wikidata - awgldk - TriplyDB

Acquisition of aneuploidy provides increased fitness during the evolution of antifungal drug resistance

Acquisition of aneuploidy provides increased fitness during the evolution of antifungal drug resistance

http://www.wikidata.org/entity/Q28476322

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Genomic Plasticity of the Human Fungal Pathogen Candida albicans Shift and adapt: the costs and benefits of karyotype variations Tipping the balance both ways: drug resistance and virulence in Candida glabrata Yeast: a simple model system to study complex phenomena of aneuploidy Aneuploidy and drug resistance in pathogenic fungi Coping with stress and the emergence of multidrug resistance in fungi Next generation multilocus sequence typing (NGMLST) and the analytical software program MLSTEZ enable efficient, cost-effective, high-throughput, multilocus sequencing typing.A tetraploid intermediate precedes aneuploid formation in yeasts exposed to fluconazole Unisexual and heterosexual meiotic reproduction generate aneuploidy and phenotypic diversity de novo in the yeast Cryptococcus neoformans Antimicrobial-induced DNA damage and genomic instability in microbial pathogens Aneuploidy underlies a multicellular phenotypic switch Deletion of Cryptococcus neoformans AIF ortholog promotes chromosome aneuploidy and fluconazole-resistance in a metacaspase-independent manner Characterization of the chromosome 4 genes that affect fluconazole-induced disomy formation in Cryptococcus neoformans Global analysis of the evolution and mechanism of echinocandin resistance in Candida glabrata Genetic and genomic architecture of the evolution of resistance to antifungal drug combinations Microevolution of Candida albicans in macrophages restores filamentation in a nonfilamentous mutant Transcriptome analysis of tetraploid cells identifies cyclin D2 as a facilitator of adaptation to genome doubling in the presence of p53 Targeting the adaptability of heterogeneous aneuploids Molecular genetic features of polyploidization and aneuploidization reveal unique patterns for genome duplication in diploid Malus Modulation of Aneuploidy in Leishmania donovani during Adaptation to Different In Vitro and In Vivo Environments and Its Impact on Gene Expression.A Population Genomics Approach to Assessing the Genetic Basis of Within-Host Microevolution Underlying Recurrent Cryptococcal Meningitis Infection.The role of chromosome missegregation in cancer development: a theoretical approach using agent-based modelling Variation in chromosome copy number influences the virulence of Cryptococcus neoformans and occurs in isolates from AIDS patients.Regulatory circuitry governing fungal development, drug resistance, and disease.Rapid mechanisms for generating genome diversity: whole ploidy shifts, aneuploidy, and loss of heterozygosity Elucidating drug resistance in human fungal pathogens.Structural basis for heterogeneous phenotype of ERG11 dependent Azole resistance in C.albicans clinical isolates Dynamic large-scale chromosomal rearrangements fuel rapid adaptation in yeast populations.Hybridization facilitates evolutionary rescue Allelic variation, aneuploidy, and nongenetic mechanisms suppress a monogenic trait in yeast.DNA copy number evolution in Drosophila cell lines Emergence of antibiotic resistance from multinucleated bacterial filaments Unisexual reproduction drives evolution of eukaryotic microbial pathogens.Too much of a good thing: the unique and repeated paths toward copper adaptation.Stress alters rates and types of loss of heterozygosity in Candida albicans.Genetic diversity among Korean Candida albicans bloodstream isolates: assessment by multilocus sequence typing and restriction endonuclease analysis of genomic DNA by use of BssHII.Silencing is noisy: population and cell level noise in telomere-adjacent genes is dependent on telomere position and sir2.The evolution of drug resistance in clinical isolates of Candida albicans The Ty1 LTR-retrotransposon of budding yeast, Saccharomyces cerevisiae The fitness consequences of aneuploidy are driven by condition-dependent gene effects.

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Acquisition of aneuploidy provides increased fitness during the evolution of antifungal drug resistance

http://www.wikidata.org/entity/Q28476322

description

2009 nî lūn-bûn

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2009 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած

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Acquisition of aneuploidy prov ...... of antifungal drug resistance

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Acquisition of aneuploidy prov ...... of antifungal drug resistance

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Acquisition of aneuploidy prov ...... of antifungal drug resistance

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Acquisition of aneuploidy prov ...... of antifungal drug resistance

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Acquisition of aneuploidy prov ...... of antifungal drug resistance

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James B Anderson

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Keely Dulmage

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P2860

Aneuploidy: cells losing their balance

Aneuploidy affects proliferation and spontaneous immortalization in mammalian cells

Species distribution and in vitro antifungal susceptibility of oral yeast isolates from Tanzanian HIV-infected patients with primary and recurrent oropharyngeal candidiasis

Mutability and importance of a hypermutable cell subpopulation that produces stress-induced mutants in Escherichia coli.

The repertoire and dynamics of evolutionary adaptations to controlled nutrient-limited environments in yeast

TAC1, transcriptional activator of CDR genes, is a new transcription factor involved in the regulation of Candida albicans ABC transporters CDR1 and CDR2.

Clinical, cellular, and molecular factors that contribute to antifungal drug resistance.

Genome-wide expression profiling of the response to azole, polyene, echinocandin, and pyrimidine antifungal agents in Candida albicans

Origin of multidrug resistance in cells with and without multidrug resistance genes: chromosome reassortments catalyzed by aneuploidy.

Specific chromosome alterations in fluconazole-resistant mutants of Candida albicans.

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