Coupled motions direct electrons along human microsomal P450 Chains
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Correlating Calmodulin Landscapes with Chemical Catalysis in Neuronal Nitric Oxide Synthase using Time-Resolved FRET and a 5-Deazaflavin Thermodynamic TrapKinetic and structural characterization of the interaction between the FMN binding domain of cytochrome P450 reductase and cytochrome c.NADPH-cytochrome P450 oxidoreductase: prototypic member of the diflavin reductase family.Co-factor binding confers substrate specificity to xylose reductase from Debaryomyces hansenii.Distinct conformational behaviors of four mammalian dual-flavin reductases (cytochrome P450 reductase, methionine synthase reductase, neuronal nitric oxide synthase, endothelial nitric oxide synthase) determine their unique catalytic profiles.Real-time analysis of conformational control in electron transfer reactions of human cytochrome P450 reductase with cytochrome cSingle-molecule spectroscopy reveals how calmodulin activates NO synthase by controlling its conformational fluctuation dynamics.Nanoscale electron transport measurements of immobilized cytochrome P450 proteins.Kinetic and spectroscopic probes of motions and catalysis in the cytochrome P450 reductase family of enzymes.Dynamic control of electron transfers in diflavin reductases.Towards the free energy landscape for catalysis in mammalian nitric oxide synthases.Instability of the Human Cytochrome P450 Reductase A287P Variant Is the Major Contributor to Its Antley-Bixler Syndrome-like Phenotype.Energy landscapes and catalysis in nitric-oxide synthase.A well-balanced preexisting equilibrium governs electron flux efficiency of a multidomain diflavin reductase.Liver microsomal lipid enhances the activity and redox coupling of colocalized cytochrome P450 reductase-cytochrome P450 3A4 in nanodiscs.Redox-linked domain movements in the catalytic cycle of cytochrome p450 reductase.Measurement of electron transfer through cytochrome P450 protein on nanopillars and the effect of bound substrates.Molecular dynamics simulations give insight into the conformational change, complex formation, and electron transfer pathway for cytochrome P450 reductase.The influence of ochratoxin A on DNA adduct formation by the carcinogen aristolochic acid in rats.Engineered control of enzyme structural dynamics and function.Structural and Kinetic Studies of Asp632 Mutants and Fully Reduced NADPH-Cytochrome P450 Oxidoreductase Define the Role of Asp632 Loop Dynamics in the Control of NADPH Binding and Hydride Transfer.Conformational change induced by electron transfer in a monolayer of cytochrome P450 reductase adsorbed at the Au(110)-phosphate buffer interface.Direct observation of multiple conformational states in Cytochrome P450 oxidoreductase and their modulation by membrane environment and ionic strengthConformational change in cytochrome P450 reductase adsorbed at a Au(110)—phosphate buffer interface induced by interaction with nicotinamide adenine dinucleotide phosphate
P2860
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P2860
Coupled motions direct electrons along human microsomal P450 Chains
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2011 nî lūn-bûn
@nan
2011 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
Coupled motions direct electrons along human microsomal P450 Chains
@ast
Coupled motions direct electrons along human microsomal P450 Chains
@en
Coupled motions direct electrons along human microsomal P450 Chains
@nl
type
label
Coupled motions direct electrons along human microsomal P450 Chains
@ast
Coupled motions direct electrons along human microsomal P450 Chains
@en
Coupled motions direct electrons along human microsomal P450 Chains
@nl
prefLabel
Coupled motions direct electrons along human microsomal P450 Chains
@ast
Coupled motions direct electrons along human microsomal P450 Chains
@en
Coupled motions direct electrons along human microsomal P450 Chains
@nl
P2093
P2860
P3181
P1433
P1476
Coupled motions direct electrons along human microsomal P450 Chains
@en
P2093
Basile Khara
Linus O Johannissen
Nigel S Scrutton
P2860
P304
P3181
P356
10.1371/JOURNAL.PBIO.1001222
P407
P577
2011-12-01T00:00:00Z