Overexpression of human and fly frataxins in Drosophila provokes deleterious effects at biochemical, physiological and developmental levels
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Novel frataxin isoforms may contribute to the pathological mechanism of Friedreich ataxiaTORC1 Inhibition by Rapamycin Promotes Antioxidant Defences in a Drosophila Model of Friedreich's AtaxiaInsertion mutants in Drosophila melanogaster Hsc20 halt larval growth and lead to reduced iron-sulfur cluster enzyme activities and impaired iron homeostasis.Iron absorption in Drosophila melanogasterTwo different pathogenic mechanisms, dying-back axonal neuropathy and pancreatic senescence, are present in the YG8R mouse model of Friedreich's ataxia.Gene regulation and epigenetics in Friedreich's ataxia.Lentivirus-meditated frataxin gene delivery reverses genome instability in Friedreich ataxia patient and mouse model fibroblastsSustained FXN expression in dorsal root ganglia from a nonreplicative genomic HSV-1 vector.Overexpression of Drosophila frataxin triggers cell death in an iron-dependent manner.Mitofusin-Dependent ER Stress Triggers Glial Dysfunction and Nervous System Degeneration in a Drosophila Model of Friedreich's Ataxia.Iron Sulfur and Molybdenum Cofactor Enzymes Regulate the Drosophila Life Cycle by Controlling Cell Metabolism.Drosophila melanogaster Models of Friedreich's Ataxia.Frataxin overexpression in Müller cells protects retinal ganglion cells in a mouse model of ischemia/reperfusion injury in vivo.Adding a temporal dimension to the study of Friedreich's ataxia: the effect of frataxin overexpression in a human cell model.Expression of the Shrimp wap gene in Drosophila elicits defense responses and protease inhibitory activity.
P2860
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P2860
Overexpression of human and fly frataxins in Drosophila provokes deleterious effects at biochemical, physiological and developmental levels
description
2011 nî lūn-bûn
@nan
2011 թուականին հրատարակուած գիտական յօդուած
@hyw
2011 թվականին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
Overexpression of human and fl ...... gical and developmental levels
@ast
Overexpression of human and fl ...... gical and developmental levels
@en
Overexpression of human and fl ...... gical and developmental levels
@nl
type
label
Overexpression of human and fl ...... gical and developmental levels
@ast
Overexpression of human and fl ...... gical and developmental levels
@en
Overexpression of human and fl ...... gical and developmental levels
@nl
prefLabel
Overexpression of human and fl ...... gical and developmental levels
@ast
Overexpression of human and fl ...... gical and developmental levels
@en
Overexpression of human and fl ...... gical and developmental levels
@nl
P2093
P2860
P3181
P1433
P1476
Overexpression of human and fl ...... gical and developmental levels
@en
P2093
José A Botella
Juan A Navarro
María J Martínez-Sebastián
Sirena Soriano
Stephan Schneuwly
P2860
P304
P3181
P356
10.1371/JOURNAL.PONE.0021017
P407
P577
2011-01-01T00:00:00Z