Frataxin interacts functionally with mitochondrial electron transport chain proteins
about
Towards a unifying, systems biology understanding of large-scale cellular death and destruction caused by poorly liganded iron: Parkinson's, Huntington's, Alzheimer's, prions, bactericides, chemical toxicology and others as examplesA pool of extramitochondrial frataxin that promotes cell survivalUnderstanding the genetic and molecular pathogenesis of Friedreich's ataxia through animal and cellular modelsInduction of oxidative metabolism by mitochondrial frataxin inhibits cancer growth: Otto Warburg revisitedIron behaving badly: inappropriate iron chelation as a major contributor to the aetiology of vascular and other progressive inflammatory and degenerative diseasesOverexpression of human and fly frataxins in Drosophila provokes deleterious effects at biochemical, physiological and developmental levelsReduced expression of mitochondrial frataxin in mice exacerbates diet-induced obesityAutosomal recessive cerebellar ataxias.In silico pathway reconstruction: Iron-sulfur cluster biogenesis in Saccharomyces cerevisiae.Flavin adenine dinucleotide rescues the phenotype of frataxin deficiency.Mitochondrial dysfunction induced by frataxin deficiency is associated with cellular senescence and abnormal calcium metabolismGAA repeat expansion mutation mouse models of Friedreich ataxia exhibit oxidative stress leading to progressive neuronal and cardiac pathology.The structure and function of frataxin.Iron-binding activity of human iron-sulfur cluster assembly protein hIscA1Friedreich's ataxia: the vicious circle hypothesis revisited.Frataxin and mitochondrial FeS cluster biogenesis.Intracellular iron transport and storage: from molecular mechanisms to health implications.Estrogen prevents oxidative damage to the mitochondria in Friedreich's ataxia skin fibroblastsMassive Uterine Leiomyoma in a Patient with Friedreich's Ataxia: Is There a Possible Association?Deletion of the Proposed Iron Chaperones IscA/SufA Results in Accumulation of a Red Intermediate Cysteine Desulfurase IscS in Escherichia coli.HSC20 interacts with frataxin and is involved in iron-sulfur cluster biogenesis and iron homeostasis.Frataxin Is Localized to Both the Chloroplast and Mitochondrion and Is Involved in Chloroplast Fe-S Protein Function in ArabidopsisAdvancements in the pathophysiology of Friedreich's Ataxia and new prospects for treatments.Mitochondrial localization of human frataxin is necessary but processing is not for rescuing frataxin deficiency in Trypanosoma brucei.Alternative mitochondrial electron transfer for the treatment of neurodegenerative diseases and cancers: Methylene blue connects the dots.Central role and mechanisms of β-cell dysfunction and death in friedreich ataxia-associated diabetes.A role of mitochondrial complex II defects in genetic models of Huntington's disease expressing N-terminal fragments of mutant huntingtinThe power of yeast to model diseases of the powerhouse of the cell.Understanding the molecular mechanisms of Friedreich's ataxia to develop therapeutic approaches.Iron-dependent functions of mitochondria--relation to neurodegeneration.Toxoplasma gondii MAF1b Binds the Host Cell MIB Complex To Mediate Mitochondrial Association.Exploring frataxin function.Impaired TCA cycle flux in mitochondria in skeletal muscle from type 2 diabetic subjects: marker or maker of the diabetic phenotype?Frataxin: a protein in search for a function.Mitochondrial pathophysiology in Friedreich's ataxia.Selected missense mutations impair frataxin processing in Friedreich ataxiaBiophysical cancer transformation pathway.Reversible Axonal Dystrophy by Calcium Modulation in Frataxin-Deficient Sensory Neurons of YG8R Mice.Nitric oxide prevents Aft1 activation and metabolic remodeling in frataxin-deficient yeast.Structural basis of the iron storage function of frataxin from single-particle reconstruction of the iron-loaded oligomer.
P2860
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P2860
Frataxin interacts functionally with mitochondrial electron transport chain proteins
description
2005 nî lūn-bûn
@nan
2005 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2005 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
2005年の論文
@ja
2005年論文
@yue
2005年論文
@zh-hant
2005年論文
@zh-hk
2005年論文
@zh-mo
2005年論文
@zh-tw
2005年论文
@wuu
name
Frataxin interacts functionally with mitochondrial electron transport chain proteins
@ast
Frataxin interacts functionally with mitochondrial electron transport chain proteins
@en
Frataxin interacts functionally with mitochondrial electron transport chain proteins
@en-gb
Frataxin interacts functionally with mitochondrial electron transport chain proteins
@nl
type
label
Frataxin interacts functionally with mitochondrial electron transport chain proteins
@ast
Frataxin interacts functionally with mitochondrial electron transport chain proteins
@en
Frataxin interacts functionally with mitochondrial electron transport chain proteins
@en-gb
Frataxin interacts functionally with mitochondrial electron transport chain proteins
@nl
prefLabel
Frataxin interacts functionally with mitochondrial electron transport chain proteins
@ast
Frataxin interacts functionally with mitochondrial electron transport chain proteins
@en
Frataxin interacts functionally with mitochondrial electron transport chain proteins
@en-gb
Frataxin interacts functionally with mitochondrial electron transport chain proteins
@nl
P50
P356
P1476
Frataxin interacts functionally with mitochondrial electron transport chain proteins
@en
P2093
M Adelaida García-Gimeno
Pilar González-Cabo
P304
P356
10.1093/HMG/DDI214
P407
P577
2005-08-01T00:00:00Z