Apilimod inhibits the production of IL-12 and IL-23 and reduces dendritic cell infiltration in psoriasis

Apilimod inhibits the production of IL-12 and IL-23 and reduces dendritic cell infiltration in psoriasis

Item
http://www.wikidata.org/entity/Q28482161
Promising new treatments for psoriasisInositol lipids: from an archaeal origin to phosphatidylinositol 3,5-bisphosphate faults in human diseaseReview: The interleukin-23/interleukin-17 axis in spondyloarthritis pathogenesis: Th17 and beyondPIKfyve, a class III PI kinase, is the target of the small molecular IL-12/IL-23 inhibitor apilimod and a player in Toll-like receptor signalingThe phosphatidylinositol-3-phosphate 5-kinase inhibitor apilimod blocks filoviral entry and infectionThe dark side of dendritic cells: development and exploitation of tolerogenic activity that favor tumor outgrowth and immune escape.Inhibition of PIKfyve prevents myocardial apoptosis and hypertrophy through activation of SIRT3 in obese mice.Toll-like receptor 9 trafficking and signaling for type I interferons requires PIKfyve activityLangerin(neg) conventional dendritic cells produce IL-23 to drive psoriatic plaque formation in mice.The IL-23/T17 pathogenic axis in psoriasis is amplified by keratinocyte responses.Autocrine interleukin-23 promotes self-renewal of CD133+ ovarian cancer stem-like cells.Role of IL-23 in the pathogenesis of psoriasis: a novel potential therapeutic target?The IL-17-Th1/Th17 pathway: an attractive target for lung cancer therapy?IL-23R is Epigenetically Regulated and Modulated by Chemotherapy in Non-Small Cell Lung Cancer.Identification of apilimod as a first-in-class PIKfyve kinase inhibitor for treatment of B-cell non-Hodgkin lymphoma.
P2860

Apilimod inhibits the production of IL-12 and IL-23 and reduces dendritic cell infiltration in psoriasis

Item
http://www.wikidata.org/entity/Q28482161
description
2012 nî lūn-bûn
@nan
2012 թուականին հրատարակուած գիտական յօդուած
@hyw
2012 թվականին հրատարակված գիտական հոդված
@hy
2012年の論文
@ja
2012年学术文章
@wuu
2012年学术文章
@zh-cn
2012年学术文章
@zh-hans
2012年学术文章
@zh-my
2012年学术文章
@zh-sg
2012年學術文章
@yue
name
Apilimod inhibits the producti ...... cell infiltration in psoriasis
@ast
Apilimod inhibits the producti ...... cell infiltration in psoriasis
@en
Apilimod inhibits the producti ...... cell infiltration in psoriasis
@nl
type
label
Apilimod inhibits the producti ...... cell infiltration in psoriasis
@ast
Apilimod inhibits the producti ...... cell infiltration in psoriasis
@en
Apilimod inhibits the producti ...... cell infiltration in psoriasis
@nl
prefLabel
Apilimod inhibits the producti ...... cell infiltration in psoriasis
@ast
Apilimod inhibits the producti ...... cell infiltration in psoriasis
@en
Apilimod inhibits the producti ...... cell infiltration in psoriasis
@nl
P1433
P1476
P2093
P2860
P304
P31
P356
P407
P433
P478
P577
P5875
P698
P932
P356
P1433
P1476
Apilimod inhibits the producti ...... cell infiltration in psoriasis
@en
P2093
P2860
P304
P31
P356
10.1371/JOURNAL.PONE.0035069
P407
P433
P478
P577
P5875
P698
P932