Autotaxin-lysophosphatidic acid axis is a novel molecular target for lowering intraocular pressure - Wikidata - awgldk - TriplyDB

Autotaxin-lysophosphatidic acid axis is a novel molecular target for lowering intraocular pressure

Autotaxin-lysophosphatidic acid axis is a novel molecular target for lowering intraocular pressure

http://www.wikidata.org/entity/Q28482420

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The Autotaxin-Lysophosphatidic Acid Axis Modulates Histone Acetylation and Gene Expression during Oligodendrocyte Differentiation What do mechanotransduction, Hippo, Wnt, and TGFβ have in common? YAP and TAZ as key orchestrating molecules in ocular health and disease.Regulation of Adherens Junctions in Trabecular Meshwork Cells by Rac GTPase and their influence on Intraocular Pressure.RhoA GTPase-induced ocular hypertension in a rodent model is associated with increased fibrogenic activity in the trabecular meshwork.Non-invasive imaging of tumors by monitoring autotaxin activity using an enzyme-activated near-infrared fluorogenic substrate.Aqueous humor phospholipids of DBA/2J and DBA/2J-Gpnmb(+)/SjJ mice.Thermally labile components of aqueous humor potently induce osteogenic potential in adipose-derived mesenchymal stem cells.Role of substratum stiffness in modulating genes associated with extracellular matrix and mechanotransducers YAP and TAZ MRP4-mediated regulation of intracellular cAMP and cGMP levels in trabecular meshwork cells and homeostasis of intraocular pressure.A proteomics view of the molecular mechanisms and biomarkers of glaucomatous neurodegeneration.Sphingolipids and ceramides in human aqueous humor.Regulation of plasticity and fibrogenic activity of trabecular meshwork cells by Rho GTPase signaling.Bioactive lysophospholipids: role in regulation of aqueous humor outflow and intraocular pressure in the context of pathobiology and therapy of glaucoma.The role and therapeutic potential of the autotaxin-lysophosphatidate signalling axis in breast cancer.Promising pharmacological directions in the world of lysophosphatidic Acid signaling.Mechanotransduction channels of the trabecular meshwork.Mutual regulation of the Hippo/Wnt/LPA/TGF‑β signaling pathways and their roles in glaucoma (Review).Lysophosphatidic Acid Induces ECM Production via Activation of the Mechanosensitive YAP/TAZ Transcriptional Pathway in Trabecular Meshwork Cells.A porcine ex vivo model of pigmentary glaucoma.

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Autotaxin-lysophosphatidic acid axis is a novel molecular target for lowering intraocular pressure

http://www.wikidata.org/entity/Q28482420

description

2012 nî lūn-bûn

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2012 թուականին հրատարակուած գիտական յօդուած

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2012 թվականին հրատարակված գիտական հոդված

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Autotaxin-lysophosphatidic aci ...... lowering intraocular pressure

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Autotaxin-lysophosphatidic aci ...... lowering intraocular pressure

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Autotaxin-lysophosphatidic aci ...... lowering intraocular pressure

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Autotaxin-lysophosphatidic aci ...... lowering intraocular pressure

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Autotaxin-lysophosphatidic aci ...... lowering intraocular pressure

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Autotaxin-lysophosphatidic aci ...... lowering intraocular pressure

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Autotaxin-lysophosphatidic aci ...... lowering intraocular pressure

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Autotaxin-lysophosphatidic aci ...... lowering intraocular pressure

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Autotaxin-lysophosphatidic aci ...... lowering intraocular pressure

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Corey Morris

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Padma Iyer

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Ponugoti Vasantha Rao

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P2860

Identification, purification, and partial sequence analysis of autotaxin, a novel motility-stimulating protein

Structural basis of substrate discrimination and integrin binding by autotaxin

Autotaxin has lysophospholipase D activity leading to tumor cell growth and motility by lysophosphatidic acid production

The number of people with glaucoma worldwide in 2010 and 2020

Crystal structure of autotaxin and insight into GPCR activation by lipid mediators

The hydrolysis of lysophospholipids and nucleotides by autotaxin (NPP2) involves a single catalytic site

Identification of human plasma lysophospholipase D, a lysophosphatidic acid-producing enzyme, as autotaxin, a multifunctional phosphodiesterase

Absolute quantification of proteins by LCMSE: a virtue of parallel MS acquisition.

Role of lysophospholipid growth factors in the modulation of aqueous humor outflow facility.

The African Descent and Glaucoma Evaluation Study (ADAGES): design and baseline data.

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