Palmitate activates autophagy in INS-1E β-cells and in isolated rat and human pancreatic islets - Wikidata - awgldk - TriplyDB

Palmitate activates autophagy in INS-1E β-cells and in isolated rat and human pancreatic islets

Palmitate activates autophagy in INS-1E β-cells and in isolated rat and human pancreatic islets

http://www.wikidata.org/entity/Q28483101

about

Novel nervous and multi-system regenerative therapeutic strategies for diabetes mellitus with mTOR FoxO Transcription Factors and Regenerative Pathways in Diabetes Mellitus Lipotoxicity in the pancreatic beta cell: not just survival and function, but proliferation as well?Erythropoietin and mTOR: A "One-Two Punch" for Aging-Related Disorders Accompanied by Enhanced Life Expectancy New Insights for Oxidative Stress and Diabetes Mellitus Association of dioxin and other persistent organic pollutants (POPs) with diabetes: epidemiological evidence and new mechanisms of beta cell dysfunction Emerging targets in lipid-based therapy Autophagy protects against palmitate-induced apoptosis in hepatocytes Age-related impairment of pancreatic Beta-cell function: pathophysiological and cellular mechanisms.Research resource: Monitoring endoplasmic reticulum membrane integrity in β-cells at the single-cell level.Unsaturated fatty acids induce non-canonical autophagy.Protection of Human Pancreatic Islets from Lipotoxicity by Modulation of the Translocon Inhibition of SCD1 impairs palmitate-derived autophagy at the step of autophagosome-lysosome fusion in pancreatic β-cells.Delayed apoptosis allows islet β-cells to implement an autophagic mechanism to promote cell survival.Co-localization of acinar markers and insulin in pancreatic cells of subjects with type 2 diabetes.Oxidant stress and signal transduction in the nervous system with the PI 3-K, Akt, and mTOR cascade Novel directions for diabetes mellitus drug discovery Mechanisms of palmitate-induced cell death in human osteoblasts.tert-Butylhydroquinone (tBHQ) protects hepatocytes against lipotoxicity via inducing autophagy independently of Nrf2 activation.Role of CYB5A in pancreatic cancer prognosis and autophagy modulation MitoNEET-Parkin Effects in Pancreatic α- and β-Cells, Cellular Survival, and Intrainsular Cross Talk.Stress-induced self-cannibalism: on the regulation of autophagy by endoplasmic reticulum stress.Autophagy in adipose tissue and the beta cell: implications for obesity and diabetes.Autophagy and cancer metabolism.Autophagy regulates insulin resistance following endoplasmic reticulum stress in diabetes.Minireview: Autophagy in pancreatic β-cells and its implication in diabetes.Programming apoptosis and autophagy with novel approaches for diabetes mellitus.Insulin-like Growth Factor 2 Overexpression Induces β-Cell Dysfunction and Increases Beta-cell Susceptibility to Damage.St. John's wort extract and hyperforin protect rat and human pancreatic islets against cytokine toxicity.Cathepsin B contributes to autophagy-related 7 (Atg7)-induced nod-like receptor 3 (NLRP3)-dependent proinflammatory response and aggravates lipotoxicity in rat insulinoma cell line.Mitigating Ischemic Injury of Stem Cell-Derived Insulin-Producing Cells after Transplant Pharmacological correction of obesity-induced autophagy arrest using calcium channel blockers.The bright side of reactive oxygen species: lifespan extension without cellular demise.Correction: palmitate activates autophagy in INS-1E β-cells and in isolated rat and human pancreatic islets.Development of fluorescence imaging probes for nicotinic acetylcholine α4β2∗ receptors.Lycium barbarum polysaccharide arbitrates palmitate-induced apoptosis in MC3T3‑E1 cells through decreasing the activation of ERS‑mediated apoptosis pathway.Ultrastructural alterations of pancreatic beta cells in human diabetes mellitus.Dysfunctional autophagy following exposure to pro-inflammatory cytokines contributes to pancreatic β-cell apoptosis.Autophagy Dysregulation and Obesity-Associated Pathologies.Pancreatic Beta Cell Death: Novel Potential Mechanisms in Diabetes Therapy.

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P2860

Palmitate activates autophagy in INS-1E β-cells and in isolated rat and human pancreatic islets

http://www.wikidata.org/entity/Q28483101

description

2012 nî lūn-bûn

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name

Palmitate activates autophagy ...... at and human pancreatic islets

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Palmitate activates autophagy ...... at and human pancreatic islets

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Palmitate activates autophagy ...... at and human pancreatic islets

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type

label

Palmitate activates autophagy ...... at and human pancreatic islets

@ast

Palmitate activates autophagy ...... at and human pancreatic islets

@en

Palmitate activates autophagy ...... at and human pancreatic islets

@nl

prefLabel

Palmitate activates autophagy ...... at and human pancreatic islets

@ast

Palmitate activates autophagy ...... at and human pancreatic islets

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Palmitate activates autophagy ...... at and human pancreatic islets

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Palmitate activates autophagy ...... at and human pancreatic islets

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Matilde Masini

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Michela Novelli

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Pellegrino Masiello

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Vincenzo De Tata

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P2860

Guidelines for the use and interpretation of assays for monitoring autophagy in higher eukaryotes

LC3, a mammalian homologue of yeast Apg8p, is localized in autophagosome membranes after processing

Autophagy in the Pathogenesis of Disease

Autophagy fights disease through cellular self-digestion

Isolation and characterization of autophagy-defective mutants of Saccharomyces cerevisiae.

Autophagy regulates lipid metabolism

The role of autophagy during the early neonatal starvation period

Development by self-digestion: molecular mechanisms and biological functions of autophagy

Autophagy is activated for cell survival after endoplasmic reticulum stress

Autophagic cell death: the story of a misnomer

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