about
Guidelines for the use and interpretation of assays for monitoring autophagyADCY5 couples glucose to insulin secretion in human isletstRNA methyltransferase homolog gene TRMT10A mutation in young onset diabetes and primary microcephaly in humansEpigenetic regulation of PPARGC1A in human type 2 diabetic islets and effect on insulin secretionLoss-of-Function Mutations in APPL1 in Familial Diabetes MellitusGliclazide protects human islet beta-cells from apoptosis induced by intermittent high glucosePalmitate activates autophagy in INS-1E β-cells and in isolated rat and human pancreatic isletsPer-arnt-sim (PAS) domain-containing protein kinase is downregulated in human islets in type 2 diabetes and regulates glucagon secretionGLIS3, a susceptibility gene for type 1 and type 2 diabetes, modulates pancreatic beta cell apoptosis via regulation of a splice variant of the BH3-only protein BimClass II phosphoinositide 3-kinase regulates exocytosis of insulin granules in pancreatic beta cellsCytokines tumor necrosis factor-α and interferon-γ induce pancreatic β-cell apoptosis through STAT1-mediated Bim protein activationp53 up-regulated modulator of apoptosis (PUMA) activation contributes to pancreatic beta-cell apoptosis induced by proinflammatory cytokines and endoplasmic reticulum stressPeripheral and islet interleukin-17 pathway activation characterizes human autoimmune diabetes and promotes cytokine-mediated β-cell deathSelective actions of mitochondrial fission/fusion genes on metabolism-secretion coupling in insulin-releasing cellsLipotoxicity disrupts incretin-regulated human β cell connectivityEffects of pancreas-kidney transplantation on diabetic retinopathy.Pancreas transplant alone has beneficial effects on retinopathy in type 1 diabetic patients.The endoplasmic reticulum in pancreatic beta cells of type 2 diabetes patients.Apoptotic, regenerative, and immune-related signaling in human islets from type 2 diabetes individuals.Palmitate induces a pro-inflammatory response in human pancreatic islets that mimics CCL2 expression by beta cells in type 2 diabetes.Type 2 diabetes susceptibility gene expression in normal or diabetic sorted human alpha and beta cells: correlations with age or BMI of islet donors.Incretin-modulated beta cell energetics in intact islets of Langerhans.Automated assessment of β-cell area and density per islet and patient using TMEM27 and BACE2 immunofluorescence staining in human pancreatic β-cells.JunB protects β-cells from lipotoxicity via the XBP1-AKT pathway.ENPP1 affects insulin action and secretion: evidences from in vitro studies.A combined "omics" approach identifies N-Myc interactor as a novel cytokine-induced regulator of IRE1 protein and c-Jun N-terminal kinase in pancreatic beta cells.Gene expression profiles of Beta-cell enriched tissue obtained by laser capture microdissection from subjects with type 2 diabetes.PTPN2, a candidate gene for type 1 diabetes, modulates pancreatic β-cell apoptosis via regulation of the BH3-only protein Bim.Altered insulin receptor signalling and β-cell cycle dynamics in type 2 diabetes mellitusThe transcription factor C/EBP delta has anti-apoptotic and anti-inflammatory roles in pancreatic beta cellsThe human pancreatic islet transcriptome: expression of candidate genes for type 1 diabetes and the impact of pro-inflammatory cytokines.Nova1 is a master regulator of alternative splicing in pancreatic beta cells.Optical control of insulin release using a photoswitchable sulfonylureaA local glucagon-like peptide 1 (GLP-1) system in human pancreatic islets.Common variant in MTNR1B associated with increased risk of type 2 diabetes and impaired early insulin secretionβ-Cell inflammation in human type 2 diabetes and the role of autophagy.Discovery of molecular pathways mediating 1,25-dihydroxyvitamin D3 protection against cytokine-induced inflammation and damage of human and male mouse islets of Langerhans.Pleiotropic effects of GIP on islet function involve osteopontin.Gluco-incretins regulate beta-cell glucose competence by epigenetic silencing of Fxyd3 expressionProceedings from an international consensus meeting on posttransplantation diabetes mellitus: recommendations and future directions.
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P50
description
hulumtues
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researcher
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ricercatore
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wetenschapper
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հետազոտող
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name
Piero Marchetti
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Piero Marchetti
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Piero Marchetti
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Piero Marchetti
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Piero Marchetti
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type
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Piero Marchetti
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Piero Marchetti
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Piero Marchetti
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Piero Marchetti
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Piero Marchetti
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prefLabel
Piero Marchetti
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Piero Marchetti
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Piero Marchetti
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Piero Marchetti
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Piero Marchetti
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P214
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J-7439-2013
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7103204997
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IT\ICCU\CFIV\203220
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