What can we learn from the evolution of protein-ligand interactions to aid the design of new therapeutics?
about
Focusing on shared subpockets - new developments in fragment-based drug discoveryInhibition of nutlin-resistant HDM2 mutants by stapled peptidesComposition of Overlapping Protein-Protein and Protein-Ligand InterfacesFlexibility and small pockets at protein-protein interfaces: New insights into druggability.Avoiding drug resistance through extended drug target interfaces: a case for stapled peptidesMolecular Property Design: Does Everyone Get It?Drug-Like Protein-Protein Interaction Modulators: Challenges and Opportunities for Drug Discovery and Chemical Biology.TIBLE: a web-based, freely accessible resource for small-molecule binding data for mycobacterial species.A systematic analysis of atomic protein-ligand interactions in the PDB.The role of ligand efficiency metrics in drug discovery.
P2860
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P2860
What can we learn from the evolution of protein-ligand interactions to aid the design of new therapeutics?
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What can we learn from the evo ...... he design of new therapeutics?
@ast
What can we learn from the evo ...... he design of new therapeutics?
@en
What can we learn from the evo ...... he design of new therapeutics?
@nl
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What can we learn from the evo ...... he design of new therapeutics?
@ast
What can we learn from the evo ...... he design of new therapeutics?
@en
What can we learn from the evo ...... he design of new therapeutics?
@nl
prefLabel
What can we learn from the evo ...... he design of new therapeutics?
@ast
What can we learn from the evo ...... he design of new therapeutics?
@en
What can we learn from the evo ...... he design of new therapeutics?
@nl
P2860
P50
P3181
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P1476
What can we learn from the evo ...... he design of new therapeutics?
@en
P2093
G Richard J Bickerton
Will R Pitt
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P304
P3181
P356
10.1371/JOURNAL.PONE.0051742
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2012-01-01T00:00:00Z