Endoxifen's molecular mechanisms of action are concentration dependent and different than that of other anti-estrogens
about
The effects of a novel hormonal breast cancer therapy, endoxifen, on the mouse skeletonThe active tamoxifen metabolite endoxifen (4OHNDtam) strongly down-regulates cytokeratin 6 (CK6) in MCF-7 breast cancer cellsComparative uterotrophic effects of endoxifen and tamoxifen in ovariectomized Sprague-Dawley rats.ERβ1: characterization, prognosis, and evaluation of treatment strategies in ERα-positive and -negative breast cancerPharmacological relevance of endoxifen in a laboratory simulation of breast cancer in postmenopausal patients.Simulation with cells in vitro of tamoxifen treatment in premenopausal breast cancer patients with different CYP2D6 genotypes.Evaluation of CYP2D6 enzyme activity using a 13C-dextromethorphan breath test in women receiving adjuvant tamoxifen.Limited predictive value of achieving beneficial plasma (Z)-endoxifen threshold level by CYP2D6 genotyping in tamoxifen-treated Polish women with breast cancer.Measuring selective estrogen receptor modulator (SERM)-membrane interactions with second harmonic generationEmerging strategies to overcome resistance to endocrine therapy for breast cancer.Tamoxifen metabolite endoxifen interferes with the polyamine pathway in breast cancer.Biocatalytic virus capsid as nanovehicle for enzymatic activation of Tamoxifen in tumor cells.ERβ inhibits cyclin dependent kinases 1 and 7 in triple negative breast cancer.Skeletal and Uterotrophic Effects of Endoxifen in Female Rats.Pharmacogenomics Guided-Personalization of Warfarin and Tamoxifen.Use of dried blood spots for the determination of serum concentrations of tamoxifen and endoxifen.Determination of tamoxifen and endoxifen in dried blood spots using LC-MS/MS and the effect of coated DBS cards on recovery and matrix effects.
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P2860
Endoxifen's molecular mechanisms of action are concentration dependent and different than that of other anti-estrogens
description
2013 nî lūn-bûn
@nan
2013 թուականին հրատարակուած գիտական յօդուած
@hyw
2013 թվականին հրատարակված գիտական հոդված
@hy
2013年の論文
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2013年論文
@yue
2013年論文
@zh-hant
2013年論文
@zh-hk
2013年論文
@zh-mo
2013年論文
@zh-tw
2013年论文
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name
Endoxifen's molecular mechanis ...... n that of other anti-estrogens
@ast
Endoxifen's molecular mechanis ...... n that of other anti-estrogens
@en
Endoxifen's molecular mechanis ...... n that of other anti-estrogens
@nl
type
label
Endoxifen's molecular mechanis ...... n that of other anti-estrogens
@ast
Endoxifen's molecular mechanis ...... n that of other anti-estrogens
@en
Endoxifen's molecular mechanis ...... n that of other anti-estrogens
@nl
prefLabel
Endoxifen's molecular mechanis ...... n that of other anti-estrogens
@ast
Endoxifen's molecular mechanis ...... n that of other anti-estrogens
@en
Endoxifen's molecular mechanis ...... n that of other anti-estrogens
@nl
P2093
P2860
P1433
P1476
Endoxifen's molecular mechanis ...... n that of other anti-estrogens
@en
P2093
Anne Gingery
James N Ingle
John R Hawse
Kevin S Pitel
Malayannan Subramaniam
Matthew P Goetz
Muzaffer Cicek
Sarah B Grygo
Thomas C Spelsberg
Wilma L Lingle
P2860
P304
P356
10.1371/JOURNAL.PONE.0054613
P407
P50
P577
2013-01-01T00:00:00Z