Estrogen receptor beta isoform-specific induction of transforming growth factor beta-inducible early gene-1 in human osteoblast cells: an essential role for the activation function 1 domain
about
Estrogen receptor β: the guardian of the endometriumEndoxifen's molecular mechanisms of action are concentration dependent and different than that of other anti-estrogensTGFβ inducible early gene-1 plays an important role in mediating estrogen signaling in the skeletonTGFbeta inducible early gene-1 directly binds to, and represses, the OPG promoter in osteoblasts.TIEG1 modulates β-catenin sub-cellular localization and enhances Wnt signaling in bone.Progression of diet induced nonalcoholic steatohepatitis is accompanied by increased expression of Kruppel-like-factor 10 in mice.Kruppel-like factor KLF10 is a link between the circadian clock and metabolism in liver.TIEG1/KLF10 modulates Runx2 expression and activity in osteoblasts.Klf10 and Klf11 as mediators of TGF-beta superfamily signaling.Sex steroid actions in male boneEstrogens and Androgens in Skeletal Physiology and Pathophysiology.Functional role of KLF10 in multiple disease processesTIEG1 enhances Osterix expression and mediates its induction by TGFβ and BMP2 in osteoblasts.Increased mandibular condylar growth in mice with estrogen receptor beta deficiency.Estrogen receptor α mediates proliferation of osteoblastic cells stimulated by estrogen and mechanical strain, but their acute down-regulation of the Wnt antagonist Sost is mediated by estrogen receptor β.Development, characterization, and applications of a novel estrogen receptor beta monoclonal antibody.A role for epithelial-mesenchymal transition in the etiology of benign prostatic hyperplasia.Tyrosine phosphorylation regulates ERβ ubiquitination, protein turnover, and inhibition of breast cancer.Support of a bi-faceted role of estrogen receptor β (ERβ) in ERα-positive breast cancer cellsTIEG and estrogen modulate SOST expression in the murine skeleton.KLF10 loss in the pancreas provokes activation of SDF-1 and induces distant metastases of pancreatic ductal adenocarcinoma in the KrasG12D p53flox/flox model.
P2860
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P2860
Estrogen receptor beta isoform-specific induction of transforming growth factor beta-inducible early gene-1 in human osteoblast cells: an essential role for the activation function 1 domain
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
2008年论文
@zh
2008年论文
@zh-cn
name
Estrogen receptor beta isoform ...... e activation function 1 domain
@ast
Estrogen receptor beta isoform ...... e activation function 1 domain
@en
type
label
Estrogen receptor beta isoform ...... e activation function 1 domain
@ast
Estrogen receptor beta isoform ...... e activation function 1 domain
@en
prefLabel
Estrogen receptor beta isoform ...... e activation function 1 domain
@ast
Estrogen receptor beta isoform ...... e activation function 1 domain
@en
P2093
P2860
P356
P1476
Estrogen receptor beta isoform ...... e activation function 1 domain
@en
P2093
Amanda H Hemmingsen
David G Monroe
James N Ingle
John R Hawse
Malayannan Subramaniam
Merry Jo Oursler
Thomas C Spelsberg
P2860
P304
P356
10.1210/ME.2007-0253
P577
2008-05-15T00:00:00Z