The crystal structure of TrpD, a metabolic enzyme essential for lung colonization by Mycobacterium tuberculosis, in complex with its substrate phosphoribosylpyrophosphate
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YbiB from Escherichia coli, the Defining Member of the Novel TrpD2 Family of Prokaryotic DNA-binding Proteins.Repurposing the chemical scaffold of the anti-arthritic drug Lobenzarit to target tryptophan biosynthesis in Mycobacterium tuberculosisStructure and inhibition of subunit I of the anthranilate synthase complex of Mycobacterium tuberculosis and expression of the active complexPhosphoribosyl Diphosphate (PRPP): Biosynthesis, Enzymology, Utilization, and Metabolic Significance.Stabilization of a metabolic enzyme by library selection in Thermus thermophilus.Analysis of IS6110 insertion sites provide a glimpse into genome evolution of Mycobacterium tuberculosis.Development of new antituberculous agents based on new drug targets and structure-activity relationship.Anthranilate phosphoribosyltransferase from the hyperthermophilic archaeon Thermococcus kodakarensis shows maximum activity with zinc and forms a unique dimeric structure.Anthranilate phosphoribosyl transferase (TrpD) generates phosphoribosylamine for thiamine synthesis from enamines and phosphoribosyl pyrophosphate.A novel inhibitor of indole-3-glycerol phosphate synthase with activity against multidrug-resistant Mycobacterium tuberculosis.Datasets, processing and refinement details for Mtb-AnPRT: inhibitor structures with various space groups.A Three-Ring Circus: Metabolism of the Three Proteogenic Aromatic Amino Acids and Their Role in the Health of Plants and Animals.Structural and Mutational Analysis of Substrate Complexation by Anthranilate Phosphoribosyltransferase fromSulfolobus solfataricus
P2860
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P2860
The crystal structure of TrpD, a metabolic enzyme essential for lung colonization by Mycobacterium tuberculosis, in complex with its substrate phosphoribosylpyrophosphate
description
2006 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2006 թվականի հունվարին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 2006
@ast
im Januar 2006 veröffentlichter wissenschaftlicher Artikel
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scientific journal article
@en
vedecký článok (publikovaný 2006/01/27)
@sk
vědecký článek publikovaný v roce 2006
@cs
wetenschappelijk artikel (gepubliceerd op 2006/01/27)
@nl
наукова стаття, опублікована в січні 2006
@uk
مقالة علمية (نشرت في 27-1-2006)
@ar
name
The crystal structure of TrpD, ...... te phosphoribosylpyrophosphate
@ast
The crystal structure of TrpD, ...... te phosphoribosylpyrophosphate
@en
The crystal structure of TrpD, ...... te phosphoribosylpyrophosphate
@nl
type
label
The crystal structure of TrpD, ...... te phosphoribosylpyrophosphate
@ast
The crystal structure of TrpD, ...... te phosphoribosylpyrophosphate
@en
The crystal structure of TrpD, ...... te phosphoribosylpyrophosphate
@nl
prefLabel
The crystal structure of TrpD, ...... te phosphoribosylpyrophosphate
@ast
The crystal structure of TrpD, ...... te phosphoribosylpyrophosphate
@en
The crystal structure of TrpD, ...... te phosphoribosylpyrophosphate
@nl
P2093
P1476
The crystal structure of TrpD, ...... te phosphoribosylpyrophosphate
@en
P2093
Catherine Goodfellow
Clare E. Lee
Edward N. Baker
Farah Javid-Majd
P304
P356
10.1016/J.JMB.2005.11.016
P407
P50
P577
2006-01-27T00:00:00Z