Leads for antitubercular compounds from kinase inhibitor library screens
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The application of tetracyclineregulated gene expression systems in the validation of novel drug targets in Mycobacterium tuberculosisTuberculosis drug discovery in the post-post-genomic eraStructural Basis for Benzothiazinone-Mediated Killing of Mycobacterium tuberculosisThe Inosine Monophosphate Dehydrogenase, GuaB2, Is a Vulnerable New Bactericidal Drug Target for Tuberculosis.New target prediction and visualization tools incorporating open source molecular fingerprints for TB Mobile 2.0Crowd sourcing a new paradigm for interactome driven drug target identification in Mycobacterium tuberculosisEnhancing hit identification in Mycobacterium tuberculosis drug discovery using validated dual-event Bayesian modelsPros and cons of the tuberculosis drugome approach--an empirical analysisEfficient Synthesis and Anti-Tubercular Activity of a Series of Spirocycles: An Exercise in Open ScienceInteraction of ATP with a small heat shock protein from Mycobacterium leprae: effect on its structure and functionTB Mobile: a mobile app for anti-tuberculosis molecules with known targetsFusing dual-event data sets for Mycobacterium tuberculosis machine learning models and their evaluation.The phosphatidyl-myo-inositol mannosyltransferase PimA is essential for Mycobacterium tuberculosis growth in vitro and in vivoThe mycobacterial cell envelope-lipidsScreening of antifungal azole drugs and agrochemicals with an adapted alamarBlue-based assay demonstrates antibacterial activity of croconazole against Mycobacterium ulcerans.The cell envelope glycoconjugates of Mycobacterium tuberculosisBayesian models leveraging bioactivity and cytotoxicity information for drug discovery.Combining computational methods for hit to lead optimization in Mycobacterium tuberculosis drug discovery.Yeast three-hybrid screening for identifying anti-tuberculosis drug targets.Syntheses and Antituberculosis Activity of 1,3-Benzothiazinone Sulfoxide and Sulfone Derived from BTZ043.Genetic Approaches to Facilitate Antibacterial Drug Development.Kinase Inhibitors that Increase the Sensitivity of Methicillin Resistant Staphylococcus aureus to β-Lactam Antibiotics.Identification of widespread adenosine nucleotide binding in Mycobacterium tuberculosisA chemical proteomics approach to profiling the ATP-binding proteome of Mycobacterium tuberculosis.Progress in targeting cell envelope biogenesis in Mycobacterium tuberculosis.Tuberculosis drugs: new candidates and how to find more.Challenges and opportunities in developing novel drugs for TB.Cytoskeletal proteins of actinobacteria.Antituberculars which target decaprenylphosphoryl-β-D-ribofuranose 2'-oxidase DprE1: state of art.Social networks to biological networks: systems biology of Mycobacterium tuberculosis.The DprE1 enzyme, one of the most vulnerable targets of Mycobacterium tuberculosis.MmpL3 a potential new target for development of novel anti-tuberculosis drugs.Trends in discovery of new drugs for tuberculosis therapy.The anti-tuberculosis agents under development and the challenges ahead.Characterization of DprE1-Mediated Benzothiazinone Resistance in Mycobacterium tuberculosis.Inhibiting Mycobacterium tuberculosis within and without.Insight into the structural requirements of aminopyrimidine derivatives for good potency against both purified enzyme and whole cells of M. tuberculosis: combination of HQSAR, CoMSIA, and MD simulation studies.Assessing the essentiality of the decaprenyl-phospho-d-arabinofuranose pathway in Mycobacterium tuberculosis using conditional mutants.Key Structures and Interactions for Binding of Mycobacterium tuberculosis Protein Kinase B Inhibitors from Molecular Dynamics Simulation.Carboxylate Surrogates Enhance the Antimycobacterial Activity of UDP-Galactopyranose Mutase Probes.
P2860
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P2860
Leads for antitubercular compounds from kinase inhibitor library screens
description
2010 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 2010
@ast
scientific journal article
@en
vedecký článok (publikovaný 2010/11/01)
@sk
vědecký článek publikovaný v roce 2010
@cs
wetenschappelijk artikel (gepubliceerd op 2010/11/01)
@nl
наукова стаття, опублікована в листопаді 2010
@uk
مقالة علمية (نشرت في نوفمبر 2010)
@ar
name
Leads for antitubercular compounds from kinase inhibitor library screens
@ast
Leads for antitubercular compounds from kinase inhibitor library screens
@en
Leads for antitubercular compounds from kinase inhibitor library screens
@nl
type
label
Leads for antitubercular compounds from kinase inhibitor library screens
@ast
Leads for antitubercular compounds from kinase inhibitor library screens
@en
Leads for antitubercular compounds from kinase inhibitor library screens
@nl
prefLabel
Leads for antitubercular compounds from kinase inhibitor library screens
@ast
Leads for antitubercular compounds from kinase inhibitor library screens
@en
Leads for antitubercular compounds from kinase inhibitor library screens
@nl
P2093
P50
P1433
P1476
Leads for antitubercular compounds from kinase inhibitor library screens
@en
P2093
Csaba Szántai-Kis
Damiano Banfi
György Kéri
James A Triccas
János Pató
Manuel Bueno
Marc Chambon
Patricia Schneider
Rita Székely
Sophie Magnet
P304
P356
10.1016/J.TUBE.2010.09.001
P577
2010-10-08T00:00:00Z