The Inosine Monophosphate Dehydrogenase, GuaB2, Is a Vulnerable New Bactericidal Drug Target for Tuberculosis.
about
Novel inhibitors of Mycobacterium tuberculosis GuaB2 identified by a target based high-throughput phenotypic screenArpeggio: A Web Server for Calculating and Visualising Interatomic Interactions in Protein StructuresGenomes, structural biology and drug discovery: combating the impacts of mutations in genetic disease and antibiotic resistance.The Bare Essentials of Antibiotic Target Validation.Combating mutations in genetic disease and drug resistance: understanding molecular mechanisms to guide drug design.N-Acetylglucosamine-1-phosphate transferase, WecA, as a validated drug target in Mycobacterium tuberculosis.Benzoxazoles, phthalazinones, and arylurea-based compounds with IMPDH-independent antibacterial activity against Francisella tularensis.Targeting DNA Replication and Repair for the Development of Novel Therapeutics against Tuberculosis.Mycobacterium tuberculosis Molecular Determinants of Infection, Survival Strategies, and Vulnerable Targets.Expanding benzoxazole based inosine 5'-monophosphate dehydrogenase (IMPDH) inhibitor structure-activity as potential anti-tuberculosis agents.Analysis of a Novel pncA Mutation for Susceptibility to Pyrazinamide Therapy.Fragment-Based Approach to Targeting Inosine-5'-monophosphate Dehydrogenase (IMPDH) from Mycobacterium tuberculosis.Kinact: a computational approach for predicting activating missense mutations in protein kinases.Molecular Targets Related Drug Resistance Mechanisms in MDR-, XDR-, and TDR-Mycobacterium tuberculosis Strains.Structural Implications of Mutations Conferring Rifampin Resistance in Mycobacterium leprae.DynaMut: predicting the impact of mutations on protein conformation, flexibility and stability.Understanding molecular consequences of putative drug resistant mutations in Mycobacterium tuberculosis
P2860
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P2860
The Inosine Monophosphate Dehydrogenase, GuaB2, Is a Vulnerable New Bactericidal Drug Target for Tuberculosis.
description
2016 nî lūn-bûn
@nan
2016 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2016 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
2016年の論文
@ja
2016年論文
@yue
2016年論文
@zh-hant
2016年論文
@zh-hk
2016年論文
@zh-mo
2016年論文
@zh-tw
2016年论文
@wuu
name
The Inosine Monophosphate Dehy ...... l Drug Target for Tuberculosis
@nl
The Inosine Monophosphate Dehy ...... Drug Target for Tuberculosis.
@ast
The Inosine Monophosphate Dehy ...... Drug Target for Tuberculosis.
@en
type
label
The Inosine Monophosphate Dehy ...... l Drug Target for Tuberculosis
@nl
The Inosine Monophosphate Dehy ...... Drug Target for Tuberculosis.
@ast
The Inosine Monophosphate Dehy ...... Drug Target for Tuberculosis.
@en
prefLabel
The Inosine Monophosphate Dehy ...... l Drug Target for Tuberculosis
@nl
The Inosine Monophosphate Dehy ...... Drug Target for Tuberculosis.
@ast
The Inosine Monophosphate Dehy ...... Drug Target for Tuberculosis.
@en
P2093
P2860
P50
P1476
The Inosine Monophosphate Dehy ...... Drug Target for Tuberculosis.
@en
P2093
Andréanne Lupien
Angela Pacitto
Anthony Vocat
David B Ascher
Guillaume Mondésert
Gyorgy Keri
Hélène Vermet
Janos Pato
Joe Buechler
John D McKinney
P2860
P356
10.1021/ACSINFECDIS.6B00102
P407
P577
2016-09-08T00:00:00Z