Adenosine kinase inhibition promotes survival of fetal adenosine deaminase-deficient thymocytes by blocking dATP accumulation
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Further differentiation of murine double-positive thymocytes is inhibited in adenosine deaminase-deficient murine fetal thymic organ cultureAutoimmune dysregulation and purine metabolism in adenosine deaminase deficiency.PRPS1 mutations: four distinct syndromes and potential treatment.CD73-generated adenosine promotes osteoblast differentiation.Adenosine deaminase deficiency: unanticipated benefits from the study of a rare immunodeficiencyComprehensive Screening of Gene Function and Networks by DNA Microarray Analysis in Japanese Patients with Idiopathic Portal Hypertension.A role for apoptosis-inducing factor in T cell development.Toll-like receptor signaling in primary immune deficiencies.Altered intracellular and extracellular signaling leads to impaired T-cell functions in ADA-SCID patients.Impaired thymopoiesis in interleukin-7 receptor transgenic mice is not corrected by Bcl-2.Restoration of adenosine deaminase-deficient human thymocyte development in vitro by inhibition of deoxynucleoside kinasesA2B adenosine receptor dampens hypoxia-induced vascular leak.CD73-generated adenosine restricts lymphocyte migration into draining lymph nodes.Inhibition of deoxynucleoside kinases in human thymocytes prevents dATP accumulation and induction of apoptosis.Adenosine Deaminase (ADA)-Deficient Severe Combined Immune Deficiency (SCID): Molecular Pathogenesis and Clinical Manifestations.
P2860
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P2860
Adenosine kinase inhibition promotes survival of fetal adenosine deaminase-deficient thymocytes by blocking dATP accumulation
description
2002 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2002 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 2002
@ast
im August 2002 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2002/08/01)
@sk
vědecký článek publikovaný v roce 2002
@cs
wetenschappelijk artikel (gepubliceerd op 2002/08/01)
@nl
наукова стаття, опублікована в серпні 2002
@uk
مقالة علمية (نشرت في أغسطس 2002)
@ar
name
Adenosine kinase inhibition pr ...... by blocking dATP accumulation
@ast
Adenosine kinase inhibition pr ...... by blocking dATP accumulation
@en
Adenosine kinase inhibition pr ...... by blocking dATP accumulation
@nl
type
label
Adenosine kinase inhibition pr ...... by blocking dATP accumulation
@ast
Adenosine kinase inhibition pr ...... by blocking dATP accumulation
@en
Adenosine kinase inhibition pr ...... by blocking dATP accumulation
@nl
prefLabel
Adenosine kinase inhibition pr ...... by blocking dATP accumulation
@ast
Adenosine kinase inhibition pr ...... by blocking dATP accumulation
@en
Adenosine kinase inhibition pr ...... by blocking dATP accumulation
@nl
P2093
P2860
P356
P1476
Adenosine kinase inhibition pr ...... by blocking dATP accumulation
@en
P2093
C. Justin Van De Wiele
Catherine A. Ledent
Hong Jiang
James G. Vaughn
Linda F. Thompson
Marlene Jacobson
Michael R. Blackburn
P2860
P304
P356
10.1172/JCI15683
P407
P577
2002-08-01T00:00:00Z