Dynamic regulation of the cerebral cavernous malformation pathway controls vascular stability and growth
about
Endothelial cell-cell adhesion during zebrafish vascular developmentCdc42 and k-Ras Control Endothelial Tubulogenesis through Apical Membrane and Cytoskeletal Polarization: Novel Stimulatory Roles for GTPase Effectors, the Small GTPases, Rac2 and Rap1b, and Inhibitory Influence of Arhgap31 and Rasa1Micro-CT Imaging Reveals Mekk3 Heterozygosity Prevents Cerebral Cavernous Malformations in Ccm2-Deficient MiceCerebral Cavernous Malformations: Review of the Genetic and Protein-Protein Interactions Resulting in Disease PathogenesisContext Specific and Differential Gene Co-expression Networks via Bayesian BiclusteringCCM2-CCM3 interaction stabilizes their protein expression and permits endothelial network formationccm2-like is required for cardiovascular development as a novel component of the Heg-CCM pathway.The cerebral cavernous malformation pathway controls cardiac development via regulation of endocardial MEKK3 signaling and KLF expression.The cerebral cavernous malformation proteins CCM2L and CCM2 prevent the activation of the MAP kinase MEKK3.Nogo-B receptor deficiency causes cerebral vasculature defects during embryonic development in mice.Cerebral cavernous malformations arise from endothelial gain of MEKK3-KLF2/4 signalling.Cerebral cavernous malformation proteins at a glance.Signaling pathways and the cerebral cavernous malformations proteins: lessons from structural biology.CCM1 and the second life of proteins in adhesion complexes.PTEN/PI3K/Akt/VEGF signaling and the cross talk to KRIT1, CCM2, and PDCD10 proteins in cerebral cavernous malformations.Molecular controls of arterial morphogenesis.Cerebral cavernous malformations arise independent of the heart of glass receptor.Src- and Fyn-dependent apical membrane trafficking events control endothelial lumen formation during vascular tube morphogenesis.Endothelial TLR4 and the microbiome drive cerebral cavernous malformations.Induction and Micro-CT Imaging of Cerebral Cavernous Malformations in Mouse Model.Ponatinib (AP24534) inhibits MEKK3-KLF signaling and prevents formation and progression of cerebral cavernous malformations
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P2860
Dynamic regulation of the cerebral cavernous malformation pathway controls vascular stability and growth
description
2012 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2012 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 2012
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im August 2012 veröffentlichter wissenschaftlicher Artikel
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scientific journal article
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vedecký článok (publikovaný 2012/08/14)
@sk
vědecký článek publikovaný v roce 2012
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wetenschappelijk artikel (gepubliceerd op 2012/08/14)
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наукова стаття, опублікована в серпні 2012
@uk
مقالة علمية (نشرت في 14-8-2012)
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name
Dynamic regulation of the cere ...... vascular stability and growth
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Dynamic regulation of the cere ...... vascular stability and growth
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Dynamic regulation of the cere ...... vascular stability and growth
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type
label
Dynamic regulation of the cere ...... vascular stability and growth
@ast
Dynamic regulation of the cere ...... vascular stability and growth
@en
Dynamic regulation of the cere ...... vascular stability and growth
@nl
prefLabel
Dynamic regulation of the cere ...... vascular stability and growth
@ast
Dynamic regulation of the cere ...... vascular stability and growth
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Dynamic regulation of the cere ...... vascular stability and growth
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P2093
P2860
P921
P3181
P1433
P1476
Dynamic regulation of the cere ...... vascular stability and growth
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P2093
Alexander Zaslavsky
Amber N. Stratman
Annie O. Smith
Aslihan Sen
Benjamin Kleaveland
Chuka Didiku
George E. Davis
Lijun Yuan
P2860
P304
P3181
P356
10.1016/J.DEVCEL.2012.06.004
P407
P577
2012-08-14T00:00:00Z