LASS5 is a bona fide dihydroceramide synthase that selectively utilizes palmitoyl-CoA as acyl donor
about
Mutations in CERS3 cause autosomal recessive congenital ichthyosis in humansNecessary role for the Lag1p motif in (dihydro)ceramide synthase activityCeramide synthases at the centre of sphingolipid metabolism and biologyMammalian ceramide synthasesThe sphingolipid salvage pathway in ceramide metabolism and signalingMale germ cells require polyenoic sphingolipids with complex glycosylation for completion of meiosis: a link to ceramide synthase-3Roles of bioactive sphingolipids in cancer biology and therapeuticsLASS3 (longevity assurance homologue 3) is a mainly testis-specific (dihydro)ceramide synthase with relatively broad substrate specificitySphingolipidomics: An Important Mechanistic Tool for Studying Fungal PathogensAlkaline Ceramidase 3 Deficiency Results in Purkinje Cell Degeneration and Cerebellar Ataxia Due to Dyshomeostasis of Sphingolipids in the BrainThe Concise Guide to PHARMACOLOGY 2013/14: enzymes.Antiapoptotic roles of ceramide-synthase-6-generated C16-ceramide via selective regulation of the ATF6/CHOP arm of ER-stress-response pathways.Alternation in the glycolipid transfer protein expression causes changes in the cellular lipidome.An introduction to sphingolipid metabolism and analysis by new technologiesSelective knockdown of ceramide synthases reveals complex interregulation of sphingolipid metabolismInhibition of fumonisin B1 cytotoxicity by nanosilicate platelets during mouse embryo development.Altered lipid levels provide evidence for myelin dysfunction in multiple system atrophy.Yeast sphingolipids: recent developments in understanding biosynthesis, regulation, and function.Developmentally regulated ceramide synthase 6 increases mitochondrial Ca2+ loading capacity and promotes apoptosis.Ceramide synthesis is modulated by the sphingosine analog FTY720 via a mixture of uncompetitive and noncompetitive inhibition in an Acyl-CoA chain length-dependent manner.Factors to consider in using [U-C]palmitate for analysis of sphingolipid biosynthesis by tandem mass spectrometry.Sphingolipid and glycosphingolipid metabolic pathways in the era of sphingolipidomics.Analysis of mammalian sphingolipids by liquid chromatography tandem mass spectrometry (LC-MS/MS) and tissue imaging mass spectrometry (TIMS).Alteration of ceramide synthase 6/C16-ceramide induces activating transcription factor 6-mediated endoplasmic reticulum (ER) stress and apoptosis via perturbation of cellular Ca2+ and ER/Golgi membrane network.Acyl chain specificity of ceramide synthases is determined within a region of 150 residues in the Tram-Lag-CLN8 (TLC) domain.Modulation of ceramide synthase activity via dimerization.LASS5 Interacts with SDHB and Synergistically Represses p53 and p21 ActivityMolecular and functional characterization of the ceramide synthase from Trypanosoma cruzi.Sphingolipids in cancer: regulation of pathogenesis and therapy.Ceramide Synthase 5 Is Essential to Maintain C16:0-Ceramide Pools and Contributes to the Development of Diet-induced Obesity.Lipidomic risk score independently and cost-effectively predicts risk of future type 2 diabetes: results from diverse cohortsCeramide signaling in cancer and stem cells.Ceramide and mitochondria in ischemia/reperfusion.Sphingolipidomics: methods for the comprehensive analysis of sphingolipids.Very long chain sphingolipids: tissue expression, function and synthesis.Ceramide and mitochondria in ischemic brain injury.Ceramide function in the brain: when a slight tilt is enough.Allylic structures in cancer drugs and body metabolites that control cell life and death.Ceramide in the regulation of eryptosis, the suicidal erythrocyte death.Adipose Fatty Acid Binding Protein Promotes Saturated Fatty Acid-Induced Macrophage Cell Death through Enhancing Ceramide Production.
P2860
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P2860
LASS5 is a bona fide dihydroceramide synthase that selectively utilizes palmitoyl-CoA as acyl donor
description
2005 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2005 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
article publié dans la revue scientifique Journal of Biological Chemistry
@fr
artículu científicu espublizáu en 2005
@ast
im Oktober 2005 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2005/10/07)
@sk
vědecký článek publikovaný v roce 2005
@cs
wetenschappelijk artikel (gepubliceerd op 2005/10/07)
@nl
наукова стаття, опублікована в жовтні 2005
@uk
name
LASS5 is a bona fide dihydroce ...... es palmitoyl-CoA as acyl donor
@ast
LASS5 is a bona fide dihydroce ...... es palmitoyl-CoA as acyl donor
@en
LASS5 is a bona fide dihydroce ...... es palmitoyl-CoA as acyl donor
@nl
type
label
LASS5 is a bona fide dihydroce ...... es palmitoyl-CoA as acyl donor
@ast
LASS5 is a bona fide dihydroce ...... es palmitoyl-CoA as acyl donor
@en
LASS5 is a bona fide dihydroce ...... es palmitoyl-CoA as acyl donor
@nl
prefLabel
LASS5 is a bona fide dihydroce ...... es palmitoyl-CoA as acyl donor
@ast
LASS5 is a bona fide dihydroce ...... es palmitoyl-CoA as acyl donor
@en
LASS5 is a bona fide dihydroce ...... es palmitoyl-CoA as acyl donor
@nl
P2860
P3181
P356
P1476
LASS5 is a bona fide dihydroce ...... es palmitoyl-CoA as acyl donor
@en
P2093
Sujoy Lahiri
P2860
P304
33735-33738
P3181
P356
10.1074/JBC.M506485200
P407
P577
2005-08-12T00:00:00Z