Antiapoptotic roles of ceramide-synthase-6-generated C16-ceramide via selective regulation of the ATF6/CHOP arm of ER-stress-response pathways.
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Ceramide synthases at the centre of sphingolipid metabolism and biologyIRF8 regulates acid ceramidase expression to mediate apoptosis and suppresses myelogeneous leukemiaMammalian ceramide synthasesAutophagy paradox and ceramideRevisiting the sphingolipid rheostat: Evolving concepts in cancer therapyClients and Oncogenic Roles of Molecular Chaperone gp96/grp94Ceramide induced mitophagy and tumor suppressionCeramide Synthase 6 Is a Novel Target of Methotrexate Mediating Its Antiproliferative Effect in a p53-Dependent MannerEctopic expression of ceramide synthase 2 in neurons suppresses neurodegeneration induced by ceramide synthase 1 deficiencyCeramide mediates FasL-induced caspase 8 activation in colon carcinoma cells to enhance FasL-induced cytotoxicity by tumor-specific cytotoxic T lymphocytesA metabolic shift favoring sphingosine 1-phosphate at the expense of ceramide controls glioblastoma angiogenesis.Celecoxib-mediated activation of endoplasmic reticulum stress induces de novo ceramide biosynthesis and apoptosis in hepatoma HepG2 cells mobilization.The impact of sphingosine kinase-1 in head and neck cancer.Re-configuration of sphingolipid metabolism by oncogenic transformation.Sphingolipids in obesity, type 2 diabetes, and metabolic disease.A hypothesis concerning a potential involvement of ceramide in apoptosis and acantholysis induced by pemphigus autoantibodies.Characteristics of the rat cardiac sphingolipid pool in two mitochondrial subpopulationsProtein kinase RNA-like endoplasmic reticulum kinase (PERK) signaling pathway plays a major role in reactive oxygen species (ROS)-mediated endoplasmic reticulum stress-induced apoptosis in diabetic cardiomyopathy.Kdo2-lipid A, a TLR4-specific agonist, induces de novo sphingolipid biosynthesis in RAW264.7 macrophages, which is essential for induction of autophagySelective knockdown of ceramide synthases reveals complex interregulation of sphingolipid metabolismApoptotic sphingolipid ceramide in cancer therapy.The retrograde response: a conserved compensatory reaction to damage from within and from without.Differential regulation of dihydroceramide desaturase by palmitate versus monounsaturated fatty acids: implications for insulin resistanceMultiplex analysis of sphingolipids using amine-reactive tags (iTRAQ)Ceramide synthase-dependent ceramide generation and programmed cell death: involvement of salvage pathway in regulating postmitochondrial events.Intraplantar-injected ceramide in rats induces hyperalgesia through an NF-κB- and p38 kinase-dependent cyclooxygenase 2/prostaglandin E2 pathway.Results of a phase II trial of gemcitabine plus doxorubicin in patients with recurrent head and neck cancers: serum C₁₈-ceramide as a novel biomarker for monitoring response.Autophagy in the light of sphingolipid metabolismFunctional characterisation of Arabidopsis SPL7 conserved protein domains suggests novel regulatory mechanisms in the Cu deficiency response.Chronic alcohol-induced hepatic insulin resistance and endoplasmic reticulum stress ameliorated by peroxisome-proliferator activated receptor-δ agonist treatmentInduction of ER stress-mediated apoptosis by ceramide via disruption of ER Ca(2+) homeostasis in human adenoid cystic carcinoma cells.Alteration of ceramide synthase 6/C16-ceramide induces activating transcription factor 6-mediated endoplasmic reticulum (ER) stress and apoptosis via perturbation of cellular Ca2+ and ER/Golgi membrane network.Sphingomyelin and sphingomyelin synthase (SMS) in the malignant transformation of glioma cells and in 2-hydroxyoleic acid therapy.Autophagy induced by deficiency of sphingosine-1-phosphate phosphohydrolase 1 is switched to apoptosis by calpain-mediated autophagy-related gene 5 (Atg5) cleavageSphingolipid signaling and hematopoietic malignancies: to the rheostat and beyond.Activating transcription factor 6 limits intracellular accumulation of mutant α(1)-antitrypsin Z and mitochondrial damage in hepatoma cells.Metabolic Conversion of Ceramides in HeLa Cells - A Cholesteryl Phosphocholine Delivery Approach.Expression of Ceramide Synthase 6 Transcriptionally Activates Acid Ceramidase in a c-Jun N-terminal Kinase (JNK)-dependent MannerA role of sphingosine kinase 1 in head and neck carcinogenesisInsulin resistance, ceramide accumulation, and endoplasmic reticulum stress in human chronic alcohol-related liver disease.
P2860
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P2860
Antiapoptotic roles of ceramide-synthase-6-generated C16-ceramide via selective regulation of the ATF6/CHOP arm of ER-stress-response pathways.
description
2009 nî lūn-bûn
@nan
2009 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2009 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
2009年の論文
@ja
2009年論文
@yue
2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
@wuu
name
Antiapoptotic roles of ceramid ...... f ER-stress-response pathways.
@ast
Antiapoptotic roles of ceramid ...... f ER-stress-response pathways.
@en
Antiapoptotic roles of ceramid ...... f ER-stress-response pathways.
@nl
type
label
Antiapoptotic roles of ceramid ...... f ER-stress-response pathways.
@ast
Antiapoptotic roles of ceramid ...... f ER-stress-response pathways.
@en
Antiapoptotic roles of ceramid ...... f ER-stress-response pathways.
@nl
prefLabel
Antiapoptotic roles of ceramid ...... f ER-stress-response pathways.
@ast
Antiapoptotic roles of ceramid ...... f ER-stress-response pathways.
@en
Antiapoptotic roles of ceramid ...... f ER-stress-response pathways.
@nl
P2093
P2860
P356
P1433
P1476
Antiapoptotic roles of ceramid ...... f ER-stress-response pathways.
@en
P2093
Besim Ogretmen
Can E Senkal
Jacek Bielawski
Suriyan Ponnusamy
P2860
P304
P356
10.1096/FJ.09-135087
P407
P577
2009-09-01T00:00:00Z