about
An atypical E3 ligase zinc finger protein 91 stabilizes and activates NF-kappaB-inducing kinase via Lys63-linked ubiquitinationTRAF3 controls activation of the canonical and alternative NFkappaB by the lymphotoxin beta receptorThe autoimmunity-associated gene PTPN22 potentiates toll-like receptor-driven, type 1 interferon-dependent immunitySUMO1 modification of NF-kappaB2/p100 is essential for stimuli-induced p100 phosphorylation and processingIs NF-kappaB a good target for cancer therapy? Hopes and pitfallsAutophagy and NF-kappaB: fight for fateNF-κB, the first quarter-century: remarkable progress and outstanding questionsRoles of tumor necrosis factor receptor associated factor 3 (TRAF3) and TRAF5 in immune cell functionsRoles of TRAF3 in T cells: many surprisesDUBA: a deubiquitinase that regulates type I interferon productionIdentification of copy number abnormalities and inactivating mutations in two negative regulators of nuclear factor-kappaB signaling pathways in Waldenstrom's macroglobulinemiaControl of RelB during dendritic cell activation integrates canonical and noncanonical NF-κB pathwaysCytosolic-DNA-mediated, STING-dependent proinflammatory gene induction necessitates canonical NF-κB activation through TBK1Non-canonical NF-κB activation and abnormal B cell accumulation in mice expressing ubiquitin protein ligase-inactive c-IAP2.Allosteric regulation of the ubiquitin:NIK and ubiquitin:TRAF3 E3 ligases by the lymphotoxin-beta receptor.TANK is a negative regulator of Toll-like receptor signaling and is critical for the prevention of autoimmune nephritis.The noncanonical NF-κB pathway.Negative feedback in noncanonical NF-kappaB signaling modulates NIK stability through IKKalpha-mediated phosphorylationHuman TRAF3 adaptor molecule deficiency leads to impaired Toll-like receptor 3 response and susceptibility to herpes simplex encephalitis.Modulation of experimental autoimmune encephalomyelitis through TRAF3-mediated suppression of interleukin 17 receptor signaling.In TNF-stimulated cells, RIPK1 promotes cell survival by stabilizing TRAF2 and cIAP1, which limits induction of non-canonical NF-kappaB and activation of caspase-8Tumor necrosis factor receptor-associated factor (TRAF) 2 controls homeostasis of the colon to prevent spontaneous development of murine inflammatory bowel disease.SUMOylation is required for optimal TRAF3 signaling capacityHuman T-cell lymphotropic virus: a model of NF-κB-associated tumorigenesisNF-κB and cancer: a paradigm of Yin-Yang.NF-κB-Mediated Regulation of OsteoclastogenesisTargeting signaling factors for degradation, an emerging mechanism for TRAF functionsPromiscuous mutations activate the noncanonical NF-kappaB pathway in multiple myeloma.Tumor necrosis factor receptor-associated factor 3 is a critical regulator of B cell homeostasis in secondary lymphoid organsHodgkin lymphoma requires stabilized NIK and constitutive RelB expression for survivalControl of canonical NF-kappaB activation through the NIK-IKK complex pathwayRoles of TRAF molecules in B lymphocyte functionNIK overexpression amplifies, whereas ablation of its TRAF3-binding domain replaces BAFF:BAFF-R-mediated survival signals in B cells.TRAF molecules in cell signaling and in human diseasesInvolvement of A20 in the molecular switch that activates the non-canonical NF-кB pathwayNoncanonical NF-kappaB activation requires coordinated assembly of a regulatory complex of the adaptors cIAP1, cIAP2, TRAF2 and TRAF3 and the kinase NIK.Lymphocyte-specific TRAF3 transgenic mice have enhanced humoral responses and develop plasmacytosis, autoimmunity, inflammation, and cancerRelB: an outlier in leukocyte biology.The BLyS family: toward a molecular understanding of B cell homeostasis.NF-kappaB p100 limits TNF-induced bone resorption in mice by a TRAF3-dependent mechanism.
P2860
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P2860
description
2006 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2006 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 2006
@ast
im Oktober 2006 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2006/10/30)
@sk
vědecký článek publikovaný v roce 2006
@cs
wetenschappelijk artikel (gepubliceerd op 2006/10/30)
@nl
наукова стаття, опублікована в жовтні 2006
@uk
مقالة علمية (نشرت في 30-10-2006)
@ar
name
Rescue of TRAF3-null mice by p100 NF-kappa B deficiency
@ast
Rescue of TRAF3-null mice by p100 NF-kappa B deficiency
@en
Rescue of TRAF3-null mice by p100 NF-kappa B deficiency
@nl
type
label
Rescue of TRAF3-null mice by p100 NF-kappa B deficiency
@ast
Rescue of TRAF3-null mice by p100 NF-kappa B deficiency
@en
Rescue of TRAF3-null mice by p100 NF-kappa B deficiency
@nl
prefLabel
Rescue of TRAF3-null mice by p100 NF-kappa B deficiency
@ast
Rescue of TRAF3-null mice by p100 NF-kappa B deficiency
@en
Rescue of TRAF3-null mice by p100 NF-kappa B deficiency
@nl
P2093
P2860
P356
P1476
Rescue of TRAF3-null mice by p100 NF-kappa B deficiency
@en
P2093
Brian Zarnegar
Gagik Oganesyan
Jeannie Q. He
Paul W. Dempsey
Sean E. Doyle
Soh Yamazaki
Supriya K. Saha
P2860
P304
P356
10.1084/JEM.20061166
P407
P577
2006-10-30T00:00:00Z