The operant serial implicit learning task reveals early onset motor learning deficits in the Hdh knock-in mouse model of Huntington's disease
about
Mouse models of polyglutamine diseases: review and data table. Part IA broad phenotypic screen identifies novel phenotypes driven by a single mutant allele in Huntington's disease CAG knock-in mice.Deficits in a Simple Visual Go/No-go Discrimination Task in Two Mouse Models of Huntington's DiseaseExtensive early motor and non-motor behavioral deficits are followed by striatal neuronal loss in knock-in Huntington's disease miceA two years longitudinal study of a transgenic Huntington disease monkey.HD mouse models reveal clear deficits in learning to perform a simple instrumental response.In Vivo MRI Evidence that Neuropathology is Attenuated by Cognitive Enrichment in the Yac128 Huntington's Disease Mouse Model.Similar striatal gene expression profiles in the striatum of the YAC128 and HdhQ150 mouse models of Huntington's disease are not reflected in mutant Huntingtin inclusion prevalence.Cognitive training modifies disease symptoms in a mouse model of Huntington's diseaseA Longitudinal Operant Assessment of Cognitive and Behavioural Changes in the HdhQ111 Mouse Model of Huntington's Disease.Brain gene expression correlates with changes in behavior in the R6/1 mouse model of Huntington's disease.Cognitive dysfunction in Huntington's disease: mechanisms and therapeutic strategies beyond BDNF.An enhanced Q175 knock-in mouse model of Huntington disease with higher mutant huntingtin levels and accelerated disease phenotypes.An Automated Home-Cage System to Assess Learning and Performance of a Skilled Motor Task in a Mouse Model of Huntington's DiseaseMutant huntingtin's effects on striatal gene expression in mice recapitulate changes observed in human Huntington's disease brain and do not differ with mutant huntingtin length or wild-type huntingtin dosage.Increased PKA signaling disrupts recognition memory and spatial memory: role in Huntington's disease.Exploring computerised cognitive training as a therapeutic intervention for people with Huntington's disease (CogTrainHD): protocol for a randomised feasibility study.
P2860
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P2860
The operant serial implicit learning task reveals early onset motor learning deficits in the Hdh knock-in mouse model of Huntington's disease
description
2007 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2007 թվականի հունվարին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 2007
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im Januar 2007 veröffentlichter wissenschaftlicher Artikel
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scientific journal article
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vedecký článok (publikovaný 2007/01/01)
@sk
vědecký článek publikovaný v roce 2007
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wetenschappelijk artikel (gepubliceerd op 2007/01/01)
@nl
наукова стаття, опублікована в січні 2007
@uk
مقالة علمية (نشرت عام 2007)
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name
The operant serial implicit le ...... model of Huntington's disease
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The operant serial implicit le ...... model of Huntington's disease
@en
The operant serial implicit le ...... model of Huntington's disease
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type
label
The operant serial implicit le ...... model of Huntington's disease
@ast
The operant serial implicit le ...... model of Huntington's disease
@en
The operant serial implicit le ...... model of Huntington's disease
@nl
prefLabel
The operant serial implicit le ...... model of Huntington's disease
@ast
The operant serial implicit le ...... model of Huntington's disease
@en
The operant serial implicit le ...... model of Huntington's disease
@nl
P2093
P2860
P3181
P1476
The operant serial implicit le ...... model of Huntington's disease
@en
P2093
Lesley Jones
Rebecca C. Trueman
Simon P. Brooks
Stephen B. Dunnett
P2860
P304
P3181
P356
10.1111/J.1460-9568.2007.05307.X
P407
P577
2007-01-01T00:00:00Z