The C terminus of p53 regulates gene expression by multiple mechanisms in a target- and tissue-specific manner in vivo
about
∆N-P63α and TA-P63α exhibit intrinsic differences in transactivation specificities that depend on distinct features of DNA target sites.Whole genome expression profiling shows that BRG1 transcriptionally regulates UV inducible genes and other novel targets in human cellsLow levels of p53 protein and chromatin silencing of p53 target genes repress apoptosis in Drosophila endocycling cells.Limiting the power of p53 through the ubiquitin proteasome pathway.Higher expression of SIRT1 induced resistance of esophageal squamous cell carcinoma cells to cisplatin.The function of Drosophila p53 isoforms in apoptosis.Cerebellum Development and Tumorigenesis: A p53-Centric Perspective.Acetylation-regulated interaction between p53 and SET reveals a widespread regulatory mode.p53 Isoforms: Key Regulators of the Cell Fate Decision.The Cell-Cycle Arrest and Apoptotic Functions of p53 in Tumor Initiation and Progression.Structural Evolution and Dynamics of the p53 Proteins.p53- and p73-independent activation of TIGAR expression in vivo.p53 downregulates the Fanconi anaemia DNA repair pathway.Wild-type p53 binds to MYC promoter G-quadruplex.Guilty as CHARGED: p53's expanding role in disease.The Roles of P53 and its Family Proteins, P63 and P73, in the DNA Damage Stress Response in Organogenesis Stage Mouse Embryos.The C-terminal domain of p53 orchestrates the interplay between non-covalent and covalent poly(ADP-ribosyl)ation of p53 by PARP1.Evidence for allosteric effects on p53 oligomerization induced by phosphorylation.Mechanisms of transcriptional regulation by p53.Valproic Acid Induces the Hyperacetylation of P53, Expression of P53 Target Genes, and Markers of the Intrinsic Apoptotic Pathway in Midorganogenesis Murine Limbs.p53 Maintains Baseline Expression of Multiple Tumor Suppressor Genes.Cancer: Acidic shield puts a chink in p53's armour.The Guardian of the Genome Revisited: p53 Downregulates Genes Required for Telomere Maintenance, DNA Repair, and Centromere Structure.The p53 C terminus controls site-specific DNA binding and promotes structural changes within the central DNA binding domain
P2860
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P2860
The C terminus of p53 regulates gene expression by multiple mechanisms in a target- and tissue-specific manner in vivo
description
2013 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2013 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 2013
@ast
im September 2013 veröffentlichter wissenschaftlicher Artikel
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scientific journal article
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vedecký článok (publikovaný 2013/09/01)
@sk
vědecký článek publikovaný v roce 2013
@cs
wetenschappelijk artikel (gepubliceerd op 2013/09/01)
@nl
наукова стаття, опублікована у вересні 2013
@uk
مقالة علمية (نشرت في سبتمبر 2013)
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name
The C terminus of p53 regulate ...... tissue-specific manner in vivo
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The C terminus of p53 regulate ...... tissue-specific manner in vivo
@en
The C terminus of p53 regulate ...... tissue-specific manner in vivo
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type
label
The C terminus of p53 regulate ...... tissue-specific manner in vivo
@ast
The C terminus of p53 regulate ...... tissue-specific manner in vivo
@en
The C terminus of p53 regulate ...... tissue-specific manner in vivo
@nl
prefLabel
The C terminus of p53 regulate ...... tissue-specific manner in vivo
@ast
The C terminus of p53 regulate ...... tissue-specific manner in vivo
@en
The C terminus of p53 regulate ...... tissue-specific manner in vivo
@nl
P2093
P2860
P3181
P356
P1433
P1476
The C terminus of p53 regulate ...... tissue-specific manner in vivo
@en
P2093
Brandon Hogstad
Emir Senturk
James J Manfredi
Luis A Carvajal
Miriam Merad
Nicolas Barthelery
Sathish Kumar Mungamuri
Stuart A Aaronson
Virginia Gillespie
P2860
P304
P3181
P356
10.1101/GAD.224386.113
P577
2013-09-01T00:00:00Z