Targeted disruption of mammalian hairy and Enhancer of split homolog-1 (HES-1) leads to up-regulation of neural helix-loop-helix factors, premature neurogenesis, and severe neural tube defects
about
Phenotypic and functional consequences of haploinsufficiency of genes from exocyst and retinoic acid pathway due to a recurrent microdeletion of 2p13.2Cardiovascular basic helix loop helix factor 1, a novel transcriptional repressor expressed preferentially in the developing and adult cardiovascular systemDevelopment and evolution of the human neocortexHes7: a bHLH-type repressor gene regulated by Notch and expressed in the presomitic mesodermHERP, a novel heterodimer partner of HES/E(spl) in Notch signalingRole of Deltex-1 as a transcriptional regulator downstream of the Notch receptorNotch signaling induces rapid degradation of achaete-scute homolog 1.Segmental expression of Notch and Hairy genes in nephrogenesisClinical features, molecular genetics, and pathophysiology of dominant optic atrophyIsolation of a murine homologue of the Drosophila neuralized gene, a gene required for axonemal integrity in spermatozoa and terminal maturation of the mammary glandHERP, a new primary target of Notch regulated by ligand bindingThe winged-helix protein brain factor 1 interacts with groucho and hes proteins to repress transcriptionHelix-loop-helix proteins: regulators of transcription in eucaryotic organismsMediation of NGF signaling by post-translational inhibition of HES-1, a basic helix-loop-helix repressor of neuronal differentiationNeuroD1/beta2 contributes to cell-specific transcription of the proopiomelanocortin geneThe basic helix-loop-helix transcription factors dHAND and eHAND exhibit dimerization characteristics that suggest complex regulation of functionHer6 regulates the neurogenetic gradient and neuronal identity in the thalamusTranscriptional oscillation of lunatic fringe is essential for somitogenesisMouse numb is an essential gene involved in cortical neurogenesisHes6 promotes cortical neurogenesis and inhibits Hes1 transcription repression activity by multiple mechanismsDelta-Notch signaling and lateral inhibition in zebrafish spinal cord developmentDifferentiation of human bone marrow stem cells into cells with a neural phenotype: diverse effects of two specific treatmentsTranscriptional regulatory network during development in the olfactory epitheliumThe role of targeted protein degradation in early neural developmentFunctional diversification of taste cells in vertebratesMASH1/Ascl1a leads to GAP43 expression and axon regeneration in the adult CNSMicroRNA-199b-5p impairs cancer stem cells through negative regulation of HES1 in medulloblastomaDefective T cell activation and autoimmune disorder in Stra13-deficient miceModulation of basic helix-loop-helix transcription complex formation by Id proteins during neuronal differentiationHES1 is a novel interactor of the Fanconi anemia core complexCombined in silico and in vivo analyses reveal role of Hes1 in taste cell differentiationHes1 is expressed in the second heart field and is required for outflow tract developmentHes1 and Hes5 as notch effectors in mammalian neuronal differentiation.Multiple requirements for Hes 1 during early eye formationMice lacking the ski proto-oncogene have defects in neurulation, craniofacial, patterning, and skeletal muscle developmentHeyL promotes neuronal differentiation of neural progenitor cellsHes1 directly controls cell proliferation through the transcriptional repression of p27Kip1Ptf1a-mediated control of Dll1 reveals an alternative to the lateral inhibition mechanismHes1 and Hes3 regulate maintenance of the isthmic organizer and development of the mid/hindbrain.Tubby-like protein 3 (TULP3) regulates patterning in the mouse embryo through inhibition of Hedgehog signaling
P2860
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P2860
Targeted disruption of mammalian hairy and Enhancer of split homolog-1 (HES-1) leads to up-regulation of neural helix-loop-helix factors, premature neurogenesis, and severe neural tube defects
description
1995 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
1995 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 1995
@ast
im Dezember 1995 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 1995/12/15)
@sk
vědecký článek publikovaný v roce 1995
@cs
wetenschappelijk artikel (gepubliceerd op 1995/12/15)
@nl
наукова стаття, опублікована в грудні 1995
@uk
научни чланак (објављен 1995/12/15)
@sr
name
Targeted disruption of mammali ...... and severe neural tube defects
@ast
Targeted disruption of mammali ...... and severe neural tube defects
@en
Targeted disruption of mammali ...... and severe neural tube defects
@nl
type
label
Targeted disruption of mammali ...... and severe neural tube defects
@ast
Targeted disruption of mammali ...... and severe neural tube defects
@en
Targeted disruption of mammali ...... and severe neural tube defects
@nl
prefLabel
Targeted disruption of mammali ...... and severe neural tube defects
@ast
Targeted disruption of mammali ...... and severe neural tube defects
@en
Targeted disruption of mammali ...... and severe neural tube defects
@nl
P2093
P3181
P356
P1433
P1476
Targeted disruption of mammali ...... and severe neural tube defects
@en
P2093
F. Guillemot
M. Ishibashi
R. Kageyama
S. Nakanishi
P304
P3181
P356
10.1101/GAD.9.24.3136
P577
1995-12-15T00:00:00Z