Leukocyte rolling and extravasation are severely compromised in P selectin-deficient mice
about
Fluids and barriers of the CNS establish immune privilege by confining immune surveillance to a two-walled castle moat surrounding the CNS castleLeukocyte adhesion to vascular endothelium induces E-selectin linkage to the actin cytoskeletonRapid secretion of prestored interleukin 8 from Weibel-Palade bodies of microvascular endothelial cellsInterleukin 4 or oncostatin M induces a prolonged increase in P-selectin mRNA and protein in human endothelial cellsIsolated P-selectin glycoprotein ligand-1 dynamic adhesion to P- and E-selectinL-selectin from human, but not from mouse neutrophils binds directly to E-selectinDifferential regulation of endothelial exocytosis of P-selectin and von Willebrand factor by protease-activated receptors and cAMPROCKs as immunomodulators of strokeEmerging roles for platelets as immune and inflammatory cellsNeuroinflammation: a common pathway in CNS diseases as mediated at the blood-brain barrierDeletion of L-selectin increases atherosclerosis development in ApoE-/- miceEarly E-selectin, VCAM-1, ICAM-1, and late major histocompatibility complex antigen induction on human endothelial cells by flavivirus and comodulation of adhesion molecule expression by immune cytokinesElucidation of the thromboregulatory role of CD39/ectoapyrase in the ischemic brainIntravital microscopy comparing T lymphocyte trafficking to the spleen and the mesenteric lymph nodeGlycosyltransferase-programmed stereosubstitution (GPS) to create HCELL: engineering a roadmap for cell migrationIndomethacin induced gastropathy in CD18, intercellular adhesion molecule 1, or P-selectin deficient miceTherapeutic potential of a novel synthetic selectin blocker, OJ-R9188, in allergic dermatitisTime course of endothelial cell proliferation and microvascular remodeling in chronic inflammationPreventive and therapeutic euphol treatment attenuates experimental colitis in miceActivated platelets induce Weibel-Palade-body secretion and leukocyte rolling in vivo: role of P-selectinCav3.1 (alpha1G) controls von Willebrand factor secretion in rat pulmonary microvascular endothelial cells.A mouse model of severe von Willebrand disease: defects in hemostasis and thrombosisP-selectin is a host receptor for Plasmodium MSP7 ligandsP-selectin and ICAM-1 mediate endotoxin-induced neutrophil recruitment and injury to the lung and liver.Severe inflammatory defect and reduced viability in CD18 and E-selectin double-mutant mice.Selectin-independent leukocyte rolling and adhesion in mice deficient in E-, P-, and L-selectin and ICAM-1.P-selectin glycoprotein ligand-1 mediates L-selectin-dependent leukocyte rolling in venules.Leukocyte adhesion molecules in animal models of inflammatory bowel diseaseAbsence of trauma-induced leukocyte rolling in mice deficient in both P-selectin and intercellular adhesion molecule 1The molecular mechanics of P- and L-selectin lectin domains binding to PSGL-1Transit time of leukocytes rolling through venules controls cytokine-induced inflammatory cell recruitment in vivoP-selectin glycoprotein ligand-1-deficient mice have impaired leukocyte tethering to E-selectin under flow.Optimal selectin-mediated rolling of leukocytes during inflammation in vivo requires intercellular adhesion molecule-1 expression.Sequential contribution of L- and P-selectin to leukocyte rolling in vivo.Both Th1 and Th2 cells require P-selectin glycoprotein ligand-1 for optimal rolling on inflamed endothelium.Suppressive effects of selectin inhibitor SKK-60060 on the leucocyte infiltration during endotoxin induced uveitis.Mice lacking the signaling molecule CalDAG-GEFI represent a model for leukocyte adhesion deficiency type III.Inflammation induces hemorrhage in thrombocytopenia.An L-selectin ligand distinct from P-selectin glycoprotein ligand-1 is expressed on endothelial cells and promotes neutrophil rolling in inflammation.Direct crosstalk between mast cell-TNF and TNFR1-expressing endothelia mediates local tissue inflammation.
P2860
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P2860
Leukocyte rolling and extravasation are severely compromised in P selectin-deficient mice
description
1993 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
1993 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 1993
@ast
im August 1993 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 1993/08/13)
@sk
vědecký článek publikovaný v roce 1993
@cs
wetenschappelijk artikel (gepubliceerd op 1993/08/13)
@nl
наукова стаття, опублікована в серпні 1993
@uk
научни чланак (објављен 1993/08/13)
@sr
name
Leukocyte rolling and extravasation are severely compromised in P selectin-deficient mice
@ast
Leukocyte rolling and extravasation are severely compromised in P selectin-deficient mice
@en
Leukocyte rolling and extravasation are severely compromised in P selectin-deficient mice
@nl
type
label
Leukocyte rolling and extravasation are severely compromised in P selectin-deficient mice
@ast
Leukocyte rolling and extravasation are severely compromised in P selectin-deficient mice
@en
Leukocyte rolling and extravasation are severely compromised in P selectin-deficient mice
@nl
prefLabel
Leukocyte rolling and extravasation are severely compromised in P selectin-deficient mice
@ast
Leukocyte rolling and extravasation are severely compromised in P selectin-deficient mice
@en
Leukocyte rolling and extravasation are severely compromised in P selectin-deficient mice
@nl
P2093
P3181
P1433
P1476
Leukocyte rolling and extravasation are severely compromised in P selectin-deficient mice
@en
P2093
D. D. Wagner
H. Rayburn
R. C. Johnson
R. O. Hynes
T. N. Mayadas
P304
P3181
P356
10.1016/0092-8674(93)80055-J
P407
P577
1993-08-13T00:00:00Z