The Wnt antagonist secreted frizzled-related protein-1 is a negative regulator of trabecular bone formation in adult mice
about
Prostaglandin E2 signals through PTGER2 to regulate sclerostin expressionRegulation of secreted Frizzled-related protein-1 by heparinSoluble frizzled-related protein 1 is estrogen inducible in bone marrow stromal cells and suppresses the earliest events in lymphopoiesisBone Fragility in Turner Syndrome: Mechanisms and Prevention StrategiesTargeting the Wnt pathways for therapiesImpact of inflammation on the osteoblast in rheumatic diseasesControl of bone mass and remodeling by PTH receptor signaling in osteocytesWNT signaling in bone homeostasis and disease: from human mutations to treatmentsRegulation of Wnt/β-catenin signaling within and from osteocytesWhere Wnts went: the exploding field of Lrp5 and Lrp6 signaling in boneSecreted Frizzled-related protein 2 is a procollagen C proteinase enhancer with a role in fibrosis associated with myocardial infarctionRegulation of osteoblastogenesis and bone mass by Wnt10bSexually dimorphic expression of secreted frizzled-related (SFRP) genes in the developing mouse Müllerian ductA DNA microarray analysis of chemokine and receptor genes in the rat dental follicle--role of secreted frizzled-related protein-1 in osteoclastogenesisSecreted frizzled related protein 1 is a paracrine modulator of epithelial branching morphogenesis, proliferation, and secretory gene expression in the prostateWnt11 promotes osteoblast maturation and mineralization through R-spondin 2Control of bone formation by the serpentine receptor Frizzled-9PTH stimulates bone formation in mice deficient in Lrp5WNT and beta-catenin signalling: diseases and therapiesSystems genetic analysis of osteoblast-lineage cellsDickkopf homolog 1 mediates endothelin-1-stimulated new bone formationWnt10b deficiency results in age-dependent loss of bone mass and progressive reduction of mesenchymal progenitor cellsGene expression analysis in human osteoblasts exposed to dexamethasone identifies altered developmental pathways as putative drivers of osteoporosis.The effect of LRP5 polymorphisms on bone mineral density is apparent in childhood.Adenomatous polyposis coli-mediated control of beta-catenin is essential for both chondrogenic and osteogenic differentiation of skeletal precursorsLef1 haploinsufficient mice display a low turnover and low bone mass phenotype in a gender- and age-specific mannerNo association of the polymorphisms of the frizzled-related protein gene with peak bone mineral density in Chinese nuclear familiesHuman 45,X fibroblast transcriptome reveals distinct differentially expressed genes including long noncoding RNAs potentially associated with the pathophysiology of Turner syndrome.Update in new anabolic therapies for osteoporosisWnts' fashion statement: from body stature to dysplasia.Bone mass is inversely proportional to Dkk1 levels in mice.Osteocyte Wnt/beta-catenin signaling is required for normal bone homeostasisSmall molecule-based disruption of the Axin/β-catenin protein complex regulates mesenchymal stem cell differentiation.The divergent roles of secreted frizzled related protein-1 (SFRP1) in lung morphogenesis and emphysema.Synergism between Wnt3a and heparin enhances osteogenesis via a phosphoinositide 3-kinase/Akt/RUNX2 pathway.Lrp5-independent activation of Wnt signaling by lithium chloride increases bone formation and bone mass in miceDeletion of a single β-catenin allele in osteocytes abolishes the bone anabolic response to loadingLrp5 is not required for the proliferative response of osteoblasts to strain but regulates proliferation and apoptosis in a cell autonomous manner.An in vivo cis-regulatory screen at the type 2 diabetes associated TCF7L2 locus identifies multiple tissue-specific enhancers.Osteocyte network; a negative regulatory system for bone mass augmented by the induction of Rankl in osteoblasts and Sost in osteocytes at unloading.
P2860
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P2860
The Wnt antagonist secreted frizzled-related protein-1 is a negative regulator of trabecular bone formation in adult mice
description
2004 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2004 թվականի մայիսին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 2004
@ast
im Mai 2004 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2004/05/01)
@sk
vědecký článek publikovaný v roce 2004
@cs
wetenschappelijk artikel (gepubliceerd op 2004/05/01)
@nl
наукова стаття, опублікована в травні 2004
@uk
مقالة علمية (نشرت في مايو 2004)
@ar
name
The Wnt antagonist secreted fr ...... r bone formation in adult mice
@ast
The Wnt antagonist secreted fr ...... r bone formation in adult mice
@en
The Wnt antagonist secreted fr ...... r bone formation in adult mice
@nl
type
label
The Wnt antagonist secreted fr ...... r bone formation in adult mice
@ast
The Wnt antagonist secreted fr ...... r bone formation in adult mice
@en
The Wnt antagonist secreted fr ...... r bone formation in adult mice
@nl
prefLabel
The Wnt antagonist secreted fr ...... r bone formation in adult mice
@ast
The Wnt antagonist secreted fr ...... r bone formation in adult mice
@en
The Wnt antagonist secreted fr ...... r bone formation in adult mice
@nl
P2093
P3181
P356
P1476
The Wnt antagonist secreted fr ...... r bone formation in adult mice
@en
P2093
Andre-Jean Lambert
Barry S. Komm
Frederick J. Bex
Gary S. Stein
Jane B. Lian
Mary Beth Goad
Peter V. N. Bodine
Tripti Gaur
Weiguang Zhao
Yogendra P. Kharode
P304
P3181
P356
10.1210/ME.2003-0498
P577
2004-05-01T00:00:00Z