Osteocyte Wnt/beta-catenin signaling is required for normal bone homeostasis - Wikidata - awgldk - TriplyDB

Osteocyte Wnt/beta-catenin signaling is required for normal bone homeostasis

Osteocyte Wnt/beta-catenin signaling is required for normal bone homeostasis

http://www.wikidata.org/entity/Q33877602

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New Insights into Wnt-Lrp5/6-β-Catenin Signaling in Mechanotransduction Craniosynostosis and multiple skeletal anomalies in humans and zebrafish result from a defect in the localized degradation of retinoic acid Effects of PTH on osteocyte function The amazing osteocyte Sclerostin Antibody Therapy for the Treatment of Osteoporosis: Clinical Prospects and Challenges The osteocyte: key player in regulating bone turnover TGF-β/BMP signaling and other molecular events: regulation of osteoblastogenesis and bone formation In vitro and in vivo approaches to study osteocyte biology Preosteocytes/osteocytes have the potential to dedifferentiate becoming a source of osteoblasts Wnt signaling in bone and muscle Potential role for therapies targeting DKK1, LRP5, and serotonin in the treatment of osteoporosis Regulation of Wnt/β-catenin signaling within and from osteocytes The Wnt serpentine receptor Frizzled-9 regulates new bone formation in fracture healing Effects of dietary phosphate on adynamic bone disease in rats with chronic kidney disease--role of sclerostin?Dickkopf-1 regulates bone formation in young growing rodents and upon traumatic injury Control of bone formation by the serpentine receptor Frizzled-9 Bone and muscle: Interactions beyond mechanical.WNT1 mutations in families affected by moderately severe and progressive recessive osteogenesis imperfecta.Osteocytes mediate the anabolic actions of canonical Wnt/β-catenin signaling in bone.Sclerostin stimulates osteocyte support of osteoclast activity by a RANKL-dependent pathway Canonical Wnt signalling activates TAZ through PP1A during osteogenic differentiation.Parathyroid hormone: anabolic and catabolic actions on the skeleton TIEG1 modulates β-catenin sub-cellular localization and enhances Wnt signaling in bone.Expression of fibroblast growth factor 23, vitamin D receptor, and sclerostin in bone tissue from hypercalciuric stone formers.Parathyroid hormone receptor signaling induces bone resorption in the adult skeleton by directly regulating the RANKL gene in osteocytes.DLX3 regulates bone mass by targeting genes supporting osteoblast differentiation and mineral homeostasis in vivo The two faces of serotonin in bone biology.Deletion of a single β-catenin allele in osteocytes abolishes the bone anabolic response to loading Osteocyte network; a negative regulatory system for bone mass augmented by the induction of Rankl in osteoblasts and Sost in osteocytes at unloading.The role of homocysteine in bone remodeling Physiological functions of osteoblast lineage and T cell-derived RANKL in bone homeostasis.Sex steroid actions in male bone β-catenin directly sequesters adipocytic and insulin sensitizing activities but not osteoblastic activity of PPARγ2 in marrow mesenchymal stem cells.Serum sclerostin is an independent predictor of mortality in hemodialysis patients Wnts produced by Osterix-expressing osteolineage cells regulate their proliferation and differentiation.Gsα enhances commitment of mesenchymal progenitors to the osteoblast lineage but restrains osteoblast differentiation in mice.PTH receptor signaling in osteocytes governs periosteal bone formation and intracortical remodeling.Suppression of autophagy in osteocytes does not modify the adverse effects of glucocorticoids on cortical bone Osteoblast-derived WNT16 represses osteoclastogenesis and prevents cortical bone fragility fractures High Bone Mass-Causing Mutant LRP5 Receptors Are Resistant to Endogenous Inhibitors In Vivo

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Osteocyte Wnt/beta-catenin signaling is required for normal bone homeostasis

http://www.wikidata.org/entity/Q33877602

description

2010 nî lūn-bûn

@nan

2010 թուականի Ապրիլին հրատարակուած գիտական յօդուած

@hyw

2010 թվականի ապրիլին հրատարակված գիտական հոդված

@hy

2010年の論文

@ja

2010年論文

@yue

2010年論文

@zh-hant

2010年論文

@zh-hk

2010年論文

@zh-mo

2010年論文

@zh-tw

2010年论文

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name

Osteocyte Wnt/beta-catenin signaling is required for normal bone homeostasis

@ast

Osteocyte Wnt/beta-catenin signaling is required for normal bone homeostasis

@en

type

label

Osteocyte Wnt/beta-catenin signaling is required for normal bone homeostasis

@ast

Osteocyte Wnt/beta-catenin signaling is required for normal bone homeostasis

@en

prefLabel

Osteocyte Wnt/beta-catenin signaling is required for normal bone homeostasis

@ast

Osteocyte Wnt/beta-catenin signaling is required for normal bone homeostasis

@en

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Molecular and Cellular Biology

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Osteocyte Wnt/beta-catenin signaling is required for normal bone homeostasis

@en

P2093

Christine Halleux

http://www.w3.org/2001/XMLSchema#string

Hansjoerg Keller

http://www.w3.org/2001/XMLSchema#string

Ina Kramer

http://www.w3.org/2001/XMLSchema#string

Jian Q Feng

http://www.w3.org/2001/XMLSchema#string

Jonathan H Gooi

http://www.w3.org/2001/XMLSchema#string

Lynda F Bonewald

http://www.w3.org/2001/XMLSchema#string

Marco Pegurri

http://www.w3.org/2001/XMLSchema#string

Michaela Kneissel

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Patricia Brander Weber

http://www.w3.org/2001/XMLSchema#string

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Activation of AXIN2 expression by beta-catenin-T cell factor. A feedback repressor pathway regulating Wnt signaling

Osteocyte control of bone formation via sclerostin, a novel BMP antagonist

osteoprotegerin-deficient mice develop early onset osteoporosis and arterial calcification

Sclerostin is an osteocyte-expressed negative regulator of bone formation, but not a classical BMP antagonist

Crystal structure of the TRANCE/RANKL cytokine reveals determinants of receptor-ligand specificity

High bone mass in mice expressing a mutant LRP5 gene

Spatial distribution of Bax and Bcl-2 in osteocytes after bone fatigue: complementary roles in bone remodeling regulation?

The Wnt co-receptor LRP5 is essential for skeletal mechanotransduction but not for the anabolic bone response to parathyroid hormone treatment

Wnt/beta-catenin signaling in mesenchymal progenitors controls osteoblast and chondrocyte differentiation during vertebrate skeletogenesis

Mechanical stimulation of bone in vivo reduces osteocyte expression of Sost/sclerostin

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3071-3085

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scholarly article

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10.1128/MCB.01428-09

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P433

12

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30

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2010-04-19T00:00:00Z

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43201456

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20404086

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2876685

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