MAP kinases and mTOR mediate insulin-induced phosphorylation of insulin receptor substrate-1 on serine residues 307, 612 and 632
about
53BP2S, interacting with insulin receptor substrates, modulates insulin signalingInsulin receptor substrate-2 is expressed in kidney epithelium and up-regulated in diabetic nephropathyTurnover of the active fraction of IRS1 involves raptor-mTOR- and S6K1-dependent serine phosphorylation in cell culture models of tuberous sclerosisSerine phosphorylation sites on IRS2 activated by angiotensin II and protein kinase C to induce selective insulin resistance in endothelial cellsProtection against the synaptic targeting and toxicity of Alzheimer's-associated Aβ oligomers by insulin mimetic chiro-inositols.Unsupervised clustering of gene expression data points at hypoxia as possible trigger for metabolic syndrome.Nitric oxide agents impair insulin-mediated signal transduction in rat skeletal muscleEffect of testosterone on insulin stimulated IRS1 Ser phosphorylation in primary rat myotubes--a potential model for PCOS-related insulin resistanceOxidative stress inhibits insulin-like growth factor-I induction of chondrocyte proteoglycan synthesis through differential regulation of phosphatidylinositol 3-Kinase-Akt and MEK-ERK MAPK signaling pathways.Insulin and metabolic stress stimulate multisite serine/threonine phosphorylation of insulin receptor substrate 1 and inhibit tyrosine phosphorylation.Tpl2 kinase is upregulated in adipose tissue in obesity and may mediate interleukin-1beta and tumor necrosis factor-{alpha} effects on extracellular signal-regulated kinase activation and lipolysis.Exercise and Glycemic Control: Focus on Redox Homeostasis and Redox-Sensitive Protein Signaling.Prostaglandin F2alpha represses IGF-I-stimulated IRS1/phosphatidylinositol-3-kinase/AKT signaling in the corpus luteum: role of ERK and P70 ribosomal S6 kinase.Effects of growth hormone and thyroxine replacement therapy on insulin signaling in Ames dwarf mice.Degradation of IRS1 leads to impaired glucose uptake in adipose tissue of the type 2 diabetes mouse model TALLYHO/JngPhosphoinositide 3-kinase catalytic subunit deletion and regulatory subunit deletion have opposite effects on insulin sensitivity in mice.Angiotensin-induced EGF receptor transactivation inhibits insulin signaling in C9 hepatic cells.Developmental programming: differential effects of prenatal testosterone excess on insulin target tissuesImproved insulin sensitivity by calorie restriction is associated with reduction of ERK and p70S6K activities in the liver of obese Zucker ratsTumor necrosis factor (TNF)-α-induced repression of GKAP42 protein levels through cGMP-dependent kinase (cGK)-Iα causes insulin resistance in 3T3-L1 adipocytesShort- and long-term glucocorticoid treatment enhances insulin signalling in human subcutaneous adipose tissue.Interleukin-6 and insulin sensitivity: friend or foe?Identification of IRS-1 Ser-1101 as a target of S6K1 in nutrient- and obesity-induced insulin resistanceRegulating insulin signaling and beta-cell function through IRS proteins.Treating insulin resistance: future prospects.Selective Insulin Resistance and the Development of Cardiovascular Diseases in Diabetes: The 2015 Edwin Bierman Award LectureHypoxia decreases insulin signaling pathways in adipocytesProlonged exposure to GH impairs insulin signaling in the heart.Systems-level interactions between insulin-EGF networks amplify mitogenic signaling.11beta-hydroxysteroid dehydrogenase type 1 regulates glucocorticoid-induced insulin resistance in skeletal muscle.Global IRS-1 phosphorylation analysis in insulin resistance.The Role of Immunogenicity in Cardiovascular Disease.Coordinated phosphorylation of insulin receptor substrate-1 by glycogen synthase kinase-3 and protein kinase C betaII in the diabetic fat tissue.Activation of mTOR: a culprit of Alzheimer's disease?Effect of insulin levels on the phosphorylation of specific amino acid residues in IRS-1: implications for burn-induced insulin resistance.Fructose-induced ROS generation impairs glucose utilization in L6 skeletal muscle cells.Interleukin-1beta-induced insulin resistance in adipocytes through down-regulation of insulin receptor substrate-1 expression.Burn injury-induced IRS-1 degradation in mouse skeletal muscle.Interplay and effects of temporal changes in the phosphorylation state of serine-302, -307, and -318 of insulin receptor substrate-1 on insulin action in skeletal muscle cellsMechanism of feedback regulation of insulin receptor substrate-1 phosphorylation in primary adipocytes
P2860
Q24298847-17F2027D-D7AA-4B1F-AEBA-9828182EA241Q24338974-9583358F-6C78-48A7-8369-7282512FC0CBQ24670558-FAA99C78-E8E8-4C9A-96D0-085C4D848E1BQ28593272-543FFBBE-AB88-46A7-88B8-3F096576B604Q30415477-354FBCFA-F93C-43BD-868F-F3576414AC27Q30478807-BA345AA3-86C9-494B-9208-E909FBDCFBB3Q33244914-5950E74C-B9BD-4C3D-8ACF-DFD15C783B50Q33402910-F613B7D9-1627-4A4E-9DA0-892C5201B251Q33553799-83A771FE-2CE2-492B-A4E7-EB6EF22FA92DQ33556119-27BA44A1-C034-48AD-95D6-21D45E380F0EQ33556670-F90AC494-4D71-497D-BBE1-AD3FFB8010CCQ33639120-4ADBFDE4-7F83-49AC-BA2A-6F31B10C9CDCQ33735911-24911A41-F5CA-4968-B23A-CDBE19884FE2Q33747568-71B4C67B-2E59-4FE6-BCD2-58C813B571D3Q33785779-2F49F847-F4F8-4A4F-9ECC-CE6E26BDAD3BQ33860786-63D5031A-49CA-46DF-85D5-AF0AF2E1030CQ34180196-BA5E9D3A-FB31-4558-B8F3-BA84E62AECD2Q34197789-4D6B7168-42C8-4640-AEB0-8D4F504BD286Q34630250-9F9D6738-2956-485B-B7C4-21DC80D9B3A4Q35126720-D18E72AA-4DA3-4E67-9F10-5B10E594472FQ35825622-45920801-D6ED-4AFA-BC78-EA7ECA8CCDC7Q35829806-1C36175B-F0F7-4004-9922-60142BC1BDD2Q35945000-305D5227-818B-406C-A963-AC6B7DBA97F3Q36602630-F1225220-4F6C-4A5B-A7A0-78E18A4553C8Q36806514-9F0AF6B8-B6A0-45FB-A2A2-365C33CE4EE0Q36930826-DF9B4901-9509-448F-BED7-A6BCEB65C545Q37023115-5989F46A-1C5D-4037-9AD6-7AB945416A02Q37102358-77EB73F9-B648-44E6-8FA5-A425A3643752Q37196175-09DA0CE1-E79B-4053-957B-E607A34C72FDQ37400786-0EAE7447-B63C-4503-B190-07753D9D6C53Q37439028-D4A46970-2C78-4BC1-973F-4B864530081FQ37560012-A6FB8436-9D8C-4036-A124-5B821969F564Q38291546-734089EB-2ADC-464E-B611-D7CCF666B807Q38443497-93E61451-15CF-4817-8314-920BF41F90B4Q39804854-A5A22A69-BBA0-4F15-B9DB-DAAB35E46293Q40945328-358D5A0A-E4E8-45EC-873E-80BD6E0A5CF0Q41862754-28159AAD-0EEF-4338-AAC5-8DDE08B7ECD0Q41893791-B427DA1F-0A25-4B90-B592-D8AC53926C5EQ42153597-2978D18D-2905-4F27-8656-3747160FCBD8Q42836867-3491EBD9-D575-42BD-8B74-E27BDCDD9EE9
P2860
MAP kinases and mTOR mediate insulin-induced phosphorylation of insulin receptor substrate-1 on serine residues 307, 612 and 632
description
2003 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2003 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 2003
@ast
im November 2003 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2003/11/01)
@sk
vědecký článek publikovaný v roce 2003
@cs
wetenschappelijk artikel (gepubliceerd op 2003/11/01)
@nl
наукова стаття, опублікована в листопаді 2003
@uk
مقالة علمية (نشرت في نوفمبر 2003)
@ar
name
MAP kinases and mTOR mediate i ...... rine residues 307, 612 and 632
@ast
MAP kinases and mTOR mediate i ...... rine residues 307, 612 and 632
@en
MAP kinases and mTOR mediate i ...... rine residues 307, 612 and 632
@nl
type
label
MAP kinases and mTOR mediate i ...... rine residues 307, 612 and 632
@ast
MAP kinases and mTOR mediate i ...... rine residues 307, 612 and 632
@en
MAP kinases and mTOR mediate i ...... rine residues 307, 612 and 632
@nl
prefLabel
MAP kinases and mTOR mediate i ...... rine residues 307, 612 and 632
@ast
MAP kinases and mTOR mediate i ...... rine residues 307, 612 and 632
@en
MAP kinases and mTOR mediate i ...... rine residues 307, 612 and 632
@nl
P2093
P921
P1433
P1476
MAP kinases and mTOR mediate i ...... rine residues 307, 612 and 632
@en
P2093
J.-F. Tanti
T. Gonzalez
T. Grémeaux
Y. Le Marchand-Brustel
P2888
P304
P356
10.1007/S00125-003-1223-4
P577
2003-11-01T00:00:00Z
P5875
P6179
1020916491